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Lysosome & C9orf72

Lysosome & C9orf72 diagram by Bandyopadhyay et al, PLOS One
Bandyopadhyay et al, PLOS One

This feed focuses on the C9orf72 protein and its possible role in lysosome function and implication in frontotemporal dementia and amyotrophic lateral sclerosis

Top 20 most recent papers
Acta Neuropathologica

DNA methylation age acceleration is associated with ALS age of onset and survival

Acta NeuropathologicaMarch 9, 2020
Ming ZhangEkaterina Rogaeva
Acta Neuropathologica

Genome-wide DNA methylation profiles distinguish silent from non-silent ACTH adenomas

Acta NeuropathologicaMarch 19, 2020
Franz L RicklefsJörg Flitsch
Frontiers in Neuroscience

The Overlapping Genetics of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

Frontiers in NeuroscienceMarch 3, 2020
Yevgeniya A AbramzonRuth Chia
Neurology. Neuroimmunology and Neuroinflammation

Inflammatory profiles relate to survival in subtypes of amyotrophic lateral sclerosis

Neurology. Neuroimmunology and NeuroinflammationMarch 4, 2020
Mads Nikolaj OlesenNasrin Asgari
Acta Neuropathologica

Histopathology of diffusion-weighted imaging-positive lesions in cerebral amyloid angiopathy

Acta NeuropathologicaFebruary 29, 2020
Annemieke Ter TelgteSusanne J van Veluw
Neurobiology of Aging

Extreme downregulation of chromosome Y and Alzheimer's disease in men

Neurobiology of AgingMarch 10, 2020
Alejandro CaceresJuan R Gonzalez
Nature Reviews. Neurology

Development of disease-modifying drugs for frontotemporal dementia spectrum disorders

Nature Reviews. NeurologyMarch 24, 2020
Francesco PanzaBruno P Imbimbo
Acta Neuropathologica

Biallelic mutations in NRROS cause an early onset lethal microgliopathy

Acta NeuropathologicaFebruary 27, 2020
Colin SmithYanick J Crow
Acta Neuropathologica

Complement deposition at the neuromuscular junction in seronegative myasthenia gravis

Acta NeuropathologicaMarch 12, 2020
Sarah HoffmannAndreas Meisel
Journal of Neurology, Neurosurgery, and Psychiatry

Different CSF protein profiles in amyotrophic lateral sclerosis and frontotemporal dementia with C9orf72 hexanucleotide repeat expansion

Journal of Neurology, Neurosurgery, and PsychiatryMarch 6, 2020
Peggy BarschkeGerman FTLD consortium

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