Lysosome & C9orf72

This feed focuses on the C9orf72 protein and its possible role in lysosome function and implication in frontotemporal dementia and amyotrophic lateral sclerosis

July 7, 2020

Zebrafish brain RNA sequencing reveals that cell adhesion molecules are critical in brain aging

Neurobiology of Aging
Begün ErbabaAyça Arslan-Ergül
July 28, 2020
Open Access

Lesion stage-dependent causes for impaired remyelination in MS

Acta Neuropathologica
Katharina HeßTanja Kuhlmann
July 9, 2020

Targeted next-generation sequencing study in familial ALS-FTD Portuguese patients negative for C9orf72 HRE

Journal of Neurology
Marta GromichoMamede de Carvalho
July 9, 2020
Open Access

Microvascular injury and hypoxic damage: emerging neuropathological signatures in COVID-19

Acta Neuropathologica
Zane JaunmuktaneSebastian Brandner
August 3, 2020

Genetics of synucleins in neurodegenerative diseases

Acta Neuropathologica
José BrásRita Guerreiro
July 28, 2020

The identified clinical features of Parkinson's disease in homo-, heterozygous and digenic variants of PINK1

Neurobiology of Aging
Arisa HayashidaNobutaka Hattori
July 22, 2020
Open Access

Metformin inhibits RAN translation through PKR pathway and mitigates disease in C9orf72 ALS/FTD mice

Proceedings of the National Academy of Sciences of the United States of America
Tao ZuLaura P W Ranum
July 15, 2020
Open Access

Receptor-like role for PQLC2 amino acid transporter in the lysosomal sensing of cationic amino acids

BioRxiv : the Preprint Server for Biology
G. TalaiaShawn Ferguson
July 31, 2020
Open Access

The physiological roles of tau and Aβ: implications for Alzheimer's disease pathology and therapeutics

Acta Neuropathologica
Sarah A KentClaire S Durrant
July 15, 2020

Thorn-shaped astrocytes in the depth of cortical sulci in Western Pacific ALS/Parkinsonism-Dementia complex

Acta Neuropathologica
Gabor G KovacsJohn Trojanowski
July 7, 2020

Peptidyl inhibition of Spt4-Spt5: Protein-protein inhibitors for targeting the transcriptional pathway related to C9orf72 expansion repeats

Journal of Cellular Biochemistry
Alexey RayevskyDmitriy Volochnyuk
July 30, 2020

Sizing, stabilising, and cloning repeat-expansions for gene targeting constructs

Methods : a Companion to Methods in Enzymology
Remya R NairThomas J Cunningham
July 15, 2020

Gray matter changes related to microglial activation in Alzheimer's disease

Neurobiology of Aging
Nicolas NicastroJohn T O'Brien
July 17, 2020

G4 C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD

Alyssa N CoyneJeffrey D Rothstein
July 31, 2020

The distinct manifestation of young-onset amyotrophic lateral sclerosis in China

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration
Jianing LinXiaoli Yao

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