Feed Preview
Lysosome & C9orf72
Bandyopadhyay et al, PLOS OneThis feed focuses on the C9orf72 protein and its possible role in lysosome function and implication in frontotemporal dementia and amyotrophic lateral sclerosis
Top 20 most recent papers
Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity
Acta NeuropathologicaJanuary 20, 2020
Sven J van der LeeHenne Holstege
6
ALS phenotype is influenced by age, sex, and genetics: A population-based study
NeurologyJanuary 8, 2020
Adriano ChiòAndrea Calvo
12
1
Correction of amyotrophic lateral sclerosis related phenotypes in induced pluripotent stem cell-derived motor neurons carrying a hexanucleotide expansion mutation in C9orf72 by CRISPR/Cas9 genome editing using homology-directed repair
bioRxivDecember 20, 2019
Nidaa AbabnehKevin Talbot
20
Aβ Puts the Alpha in Synuclein
NeuronJanuary 24, 2020
Casey Cook, L Petrucelli
Fulminant corticobasal degeneration: a distinct variant with predominant neuronal tau aggregates
Acta NeuropathologicaJanuary 18, 2020
Helen LingTamas Revesz
16
1
An update on the CNS manifestations of brain tumor polyposis syndromes
Acta NeuropathologicaJanuary 24, 2020
Byungjin KimCynthia Hawkins
Trajectory of lobar atrophy in asymptomatic and symptomatic GRN mutation carriers: a longitudinal MRI study
Neurobiology of AgingJanuary 11, 2020
Qin ChenK Kantarci
1
1
Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint
Alzheimer's & Dementia : the Journal of the Alzheimer's AssociationJanuary 9, 2020
A M StaffaroniARTFL/LEFFTDS consortium
Loss of H3K27 trimethylation by immunohistochemistry is frequent in oligodendroglioma, IDH-mutant and 1p/19q-codeleted, but is neither a sensitive nor a specific marker
Acta NeuropathologicaJanuary 9, 2020
Melike PekmezciArie Perry
4
Familial globular glial tauopathy linked to MAPT mutations: molecular neuropathology and seeding capacity of a prototypical mixed neuronal and glial tauopathy
Acta NeuropathologicaJanuary 8, 2020
Isidro FerrerJosé Antonio Del Rio
2
Antibody signatures in patients with histopathologically defined multiple sclerosis patterns
Acta NeuropathologicaJanuary 18, 2020
Lidia StorkImke Metz
4
Picalm reduction exacerbates tau pathology in a murine tauopathy model
Acta NeuropathologicaJanuary 12, 2020
Kunie AndoJean-Pierre Brion
8
1
Distance disintegration delineates the brain connectivity failure of Alzheimer's disease
Neurobiology of AgingJanuary 17, 2020
Víctor CostumeroJorge Sepulcre
1
18F]Flortaucipir distinguishes Alzheimer's disease from progressive supranuclear palsy pathology in a mixed-pathology case
Acta NeuropathologicaJanuary 7, 2020
Ruben SmithOskar Hansson
1
Age differences in the fronto-striato-parietal network underlying serial ordering
Neurobiology of AgingJanuary 11, 2020
Zheng YeThomas F Münte
Rare IDH1 variants are common in pediatric hemispheric diffuse astrocytomas and frequently associated with Li-Fraumeni syndrome
Acta NeuropathologicaJanuary 4, 2020
David SumerauerMichal Zapotocky
3
Analysis of brain atrophy and local gene expression implicates astrocytes in Frontotemporal dementia
bioRxivDecember 12, 2019
Andre Altmannon behalf of the Genetic FTD Initiative, GENFI.
21
Cross-sectional and longitudinal measures of chitinase proteins in amyotrophic lateral sclerosis and expression of CHI3L1 in activated astrocytes
Journal of Neurology, Neurosurgery, and PsychiatryJanuary 16, 2020
Lucas VuRobert Bowser
3
1
POGLUT1 biallelic mutations cause myopathy with reduced satellite cells, α-dystroglycan hypoglycosylation and a distinctive radiological pattern
Acta NeuropathologicaJanuary 4, 2020
E Servián-MorillaCarmen Paradas
3
Nonlinear Z-score modeling for improved detection of cognitive abnormality
Alzheimer's & Dementia : Diagnosis, Assessment & Disease MonitoringDecember 25, 2019
J KornakARTFL/LEFFTDS consortium
2