Lysosome & C9orf72

This feed focuses on the C9orf72 protein and its possible role in lysosome function and implication in frontotemporal dementia and amyotrophic lateral sclerosis

January 10, 2021

Longitudinal changes in network homogeneity in presymptomatic C9orf72 mutation carriers

Neurobiology of Aging
Rebecca E WaughMary Kay Floeter
January 9, 2021
Open Access

Exosomes induce endolysosomal permeabilization as a gateway by which exosomal tau seeds escape into the cytosol

Acta Neuropathologica
Juan Carlos PolancoJürgen Götz
January 6, 2021
Open Access

Neuropathological consensus criteria for the evaluation of Lewy pathology in post-mortem brains: a multi-centre study

Acta Neuropathologica
Johannes AttemsIan G McKeith
January 16, 2021

Making sense of missense variants in TTN-related congenital myopathies

Acta Neuropathologica
Martin ReesMathias Gautel
January 2, 2021
Open Access

In vitro amplification of pathogenic tau conserves disease-specific bioactive characteristics

Acta Neuropathologica
Hong XuVirginia M-Y Lee
January 13, 2021
Open Access

Mutations within FGFR1 are associated with superior outcome in a series of 83 diffuse midline gliomas with H3F3A K27M mutations

Acta Neuropathologica
Ulrich SchüllerJulia E Neumann
December 29, 2020
Open Access

LSM12-EPAC1 defines a neuroprotective pathway that sustains the nucleocytoplasmic RAN gradient

PLoS Biology
Jongbo LeeChunghun Lim
January 8, 2021
Open Access

Enhanced detection of nucleotide repeat mRNA with hybridization chain reaction

BioRxiv : the Preprint Server for Biology
M. R. GlineburgPeter Todd
January 8, 2021

Extra-motor cerebral changes and manifestations in primary lateral sclerosis

Brain Imaging and Behavior
Eoin FineganPeter Bede
January 7, 2021
Open Access

Progression of Behavioral Disturbances and Neuropsychiatric Symptoms in Patients With Genetic Frontotemporal Dementia

JAMA Network Open
Alberto BenussiGenetic FTD Initiative (GENFI)
January 13, 2021

A Multi-omics Data Resource for Frontotemporal Dementia Research

Advances in Experimental Medicine and Biology
Peter HeutinkAnupriya Dalmia
January 11, 2021
Open Access

Dystrophic microglia are associated with neurodegenerative disease and not healthy aging in the human brain

Neurobiology of Aging
Ryan K ShahidehpourAdam D Bachstetter
December 31, 2020

Investigating TBP CAG/CAA trinucleotide repeat expansions in a Taiwanese cohort with ALS

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration
Kang-Yang JihYi-Chung Lee
January 9, 2021
Open Access

Genetic analysis of ALS cases in the isolated island population of Malta

European Journal of Human Genetics : EJHG
Rebecca BorgRuben J Cauchi
January 3, 2021

Physiological and pathological functions of TMEM106B: a gene associated with brain aging and multiple brain disorders

Acta Neuropathologica
Tuancheng FengFenghua Hu
January 11, 2021

Volumetric distribution of perivascular space in relation to mild cognitive impairment

Neurobiology of Aging
Farshid SepehrbandAlzheimer’s Disease Neuroimaging Initiative

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