Mammalian Cells & Synthetic Biology

Mammalian cells & synthetic biology describes the recent advancements in mammalian synthetic biology where new technologies and tools are developed to programm and probe mammalian cell behaviours that can lead to potential therapeutic applications. Discover the latest research on mammalian cells and synthetic biology here.

April 9, 2020
Open Access

Cell biomechanics and mechanobiology in bacteria: Challenges and opportunities

APL Bioengineering
Christine E Harper, Christopher J Hernandez
May 19, 2020

Engineering Intracellular Protein Sensors in Mammalian Cells

Journal of Visualized Experiments : JoVE
Marina DuhkinovaVelia Siciliano
June 18, 2020
Open Access

An Integrative Synthetic Biology Approach to Interrogating Cellular Ubiquitin and Ufm Signaling

International Journal of Molecular Sciences
Chuanyin LiRonggui Hu
March 10, 2020
Open Access

The enigma of DNA methylation in the mammalian oocyte

Hannah Demond, Gavin Kelsey
February 22, 2020
Open Access

A Conserved Mito-Cytosolic Translational Balance Links Two Longevity Pathways

Cell Metabolism
Marte MolenaarsRiekelt H Houtkooper
May 27, 2020

Programming switchable transcription of topologically constrained DNA

Journal of the American Chemical Society
Kai JiaoChunhai Fan
April 25, 2020
Open Access

The anti-lipidemic drug simvastatin modulates Epigenetic Biomarkers in the Amphipod Gammarus locusta

BioRxiv : the Preprint Server for Biology
N. AlvesMiguel M. Santos
May 1, 2020
Open Access

Tunable self-cleaving ribozymes for modulating gene expression in eukaryotic systems

PloS One
Thomas JacobsenGregory T Reeves
June 6, 2020
Open Access

Argonaute binding within 3'-untranslated regions poorly predicts gene repression

Nucleic Acids Research
Yongjun ChuDavid R Corey
April 4, 2020

Noncoding RNA MaIL1 is an integral component of the TLR4-TRIF pathway

Proceedings of the National Academy of Sciences of the United States of America
Marina AznaourovaLeon N Schulte
February 22, 2020
Open Access

Mutual Regulation of RNA Silencing and the IFN Response as an Antiviral Defense System in Mammalian Cells

International Journal of Molecular Sciences
Tomoko Takahashi, Kumiko Ui-Tei
March 19, 2020
Open Access

Building sophisticated sensors of extracellular cues that enable mammalian cells to work as "doctors" in the body

Cellular and Molecular Life Sciences : CMLS
Ryosuke KojimaMartin Fussenegger
March 20, 2020
Open Access

The replisome guides nucleosome assembly during DNA replication

Cell & Bioscience
Wenshuo ZhangQing Li
March 27, 2020
Open Access

Engineering Cellular Signal Sensors based on CRISPR-sgRNA Reconstruction Approaches

International Journal of Biological Sciences
Hengji ZhanYuchen Liu
March 24, 2020

The origin of genomic N6 -methyl-deoxyadenosine in mammalian cells

Nature Chemical Biology
Michael U MusheevChristof Niehrs
March 11, 2020
Open Access

A gene signal amplifier platform for monitoring the unfolded protein response

Nature Chemical Biology
Carlos A Origel MarmolejoLaura Segatori
March 17, 2020

Effects of Chemical Modifications on siRNA Strand Selection in Mammalian Cells

Nucleic Acid Therapeutics
Andrew J VarleyJean-Paul Desaulniers

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