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Mammalian Cells & Synthetic Biology

Mammalian Cells & Synthetic Biology diagram by Connor et al, Wikimedia
Connor et al, Wikimedia

Mammalian cells & synthetic biology describes the recent advancements in mammalian synthetic biology where new technologies and tools are developed to programm and probe mammalian cell behaviours that can lead to potential therapeutic applications. Discover the latest research on mammalian cells and synthetic biology here.

Top 20 most recent papers
Molecular Therapy. Nucleic Acids

In Vivo RNAi-Mediated eIF3m Knockdown Affects Ribosome Biogenesis and Transcription but Has Limited Impact on mRNA-Specific Translation

Molecular Therapy. Nucleic AcidsDecember 20, 2019
Elena M SmekalovaVictor Koteliansky

Cellular state determines the multimodal signaling response of single cells

bioRxivDecember 19, 2019
Bernhard A. Kramer, Lucas Pelkmans

A novel mycovirus evokes transcriptional rewiring in Malassezia and provokes host inflammation and an immunological response

bioRxivDecember 19, 2019
Shelly Applen ClanceyGiuseppe Ianiri

Overcoming the design, build, test (DBT) bottleneck for synthesis of nonrepetitive protein-RNA binding cassettes for RNA applications

bioRxivDecember 26, 2019
Noa KatzRoee Amit

PERSIST: A programmable RNA regulation platform using CRISPR endoRNases

bioRxivDecember 16, 2019
Breanna DiAndrethRon Weiss

Simulation of the Gαq /Phospholipase Cβ1 Signaling Pathway Returns Differentiated PC12 Cells to a Stem-like State

bioRxivJanuary 6, 2020
Osama GarwainSuzanne S Scarlata

Serotonin signaling by maternal neurons upon stress ensures progeny survival

bioRxivJanuary 21, 2020
Srijit DasVeena Prahlad
The FEBS Journal

Broad domains of histone H3 lysine 4 trimethylation in transcriptional regulation and disease

The FEBS JournalJanuary 23, 2020
Shinae ParkJung-Shin Lee

Epigenetic engineering of yeast reveals dynamic molecular adaptation to methylation stress and genetic modulators of specific DNMT3 family members

bioRxivJanuary 26, 2020
Alex I FinneganJun S. Song
Journal of Clinical Medicine

Expression of Taste Receptor 2 Subtypes in Human Testis and Sperm

Journal of Clinical MedicineJanuary 23, 2020
Laura GoverniniPaola Piomboni
Methods in Molecular Biology

Engineering Mutation Clones in Mammalian Cells with CRISPR/Cas9

Methods in Molecular BiologyJanuary 16, 2020
Zijun HuoRuiying Zhao
Nature Methods

Biophysical prediction of protein-peptide interactions and signaling networks using machine learning

Nature MethodsJanuary 8, 2020
Joseph M CunninghamMohammed AlQuraishi
Journal of Biosciences

Cellular environment controls the dynamics of histone H3 lysine 56 acetylation in response to DNA damage in mammalian cells

Journal of BiosciencesJanuary 23, 2020
Raghavendra VadlaDevyani Haldar

Reduced function of the glutathione S-transferase S1 suppresses behavioral hyperexcitability in Drosophila expressing a mutant voltage-gated sodium channel

bioRxivJanuary 21, 2020
Hung-Lin ChenToshihiro Kitamoto

Characterizing expression of candidate genes of a glutamate receptor pathway in Arabidopsis thaliana using real-time RT-PCR

bioRxivJanuary 25, 2020
Julie Wurdeman, Tessa Durham Brooks
International Journal of Molecular Sciences

Cannabinoid Receptors Signaling in the Development, Epigenetics, and Tumours of Male Germ Cells

International Journal of Molecular SciencesDecember 22, 2019
Marco BarchiPaola Grimaldi
Restorative Neurology and Neuroscience

Lab review: Molecular dissection of the signal transduction pathways associated with PTEN deletion-induced optic nerve regeneration

Restorative Neurology and NeuroscienceDecember 17, 2019
Haoliang HuangYang Hu
International Journal of Biological Macromolecules

Cyclic GMP-AMP synthase is essential for cytosolic double-stranded DNA and fowl adenovirus serotype 4 triggered innate immune responses in chickens

International Journal of Biological MacromoleculesJanuary 11, 2020
Jiang WangBei-Bei Chu

m6 A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination

NeuronJanuary 7, 2020
Huan XuBrian Popko
Nature Chemical Biology

Artificial signaling in mammalian cells enabled by prokaryotic two-component system

Nature Chemical BiologyDecember 18, 2019
Alain Mazé, Yaakov Benenson

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