Mammalian Cells & Synthetic Biology

Mammalian cells & synthetic biology describes the recent advancements in mammalian synthetic biology where new technologies and tools are developed to programm and probe mammalian cell behaviours that can lead to potential therapeutic applications. Discover the latest research on mammalian cells and synthetic biology here.

September 17, 2020

Quantitative genetic screening reveals a Ragulator-FLCN feedback loop that regulates the mTORC1 pathway

Science Signaling
Erica De ZanSebastian M B Nijman
June 18, 2020
Open Access

An Integrative Synthetic Biology Approach to Interrogating Cellular Ubiquitin and Ufm Signaling

International Journal of Molecular Sciences
Chuanyin LiRonggui Hu
July 12, 2020

Optogenetics and CRISPR: A New Relationship Built to Last

Methods in Molecular Biology
Jan MathonyDominik Niopek
May 27, 2020

Programming switchable transcription of topologically constrained DNA

Journal of the American Chemical Society
Kai JiaoChunhai Fan
September 15, 2020

A Two-Step Strategy that Combines Epigenetic Modification and Biomechanical Cues to Generate Mammalian Pluripotent Cells

Journal of Visualized Experiments : JoVE
Georgia PennarossaTiziana A L Brevini
July 9, 2020
Open Access

Nutrient Sensing by Histone Marks: Reading the Metabolic Histone Code Using Tracing, Omics, and Modeling

BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology
Scott E CampitSriram Chandrasekaran
June 6, 2020
Open Access

Argonaute binding within 3'-untranslated regions poorly predicts gene repression

Nucleic Acids Research
Yongjun ChuDavid R Corey
September 10, 2020
Open Access

Nanobody-mediated control of gene expression and epigenetic memory

BioRxiv : the Preprint Server for Biology
M. V. VanLacramioara Bintu
August 19, 2020

Making it or breaking it: DNA methylation and genome integrity

Essays in Biochemistry
Anusha SriramanKyle M Miller
August 31, 2020

Small-molecule inducible transcriptional control in mammalian cells

Critical Reviews in Biotechnology
Aarti DoshiPatrick C Cirino
June 17, 2020
Open Access

ROS regulation of RAS and vulva development in Caenorhabditis elegans

PLoS Genetics
Maximilian Kramer-DraubergSiegfried Hekimi
August 5, 2020
Open Access

An overview of signaling pathways regulating YAP/TAZ activity

Cellular and Molecular Life Sciences : CMLS
Boon Chin HengXuliang Deng
May 30, 2020
Open Access

The Effects of Cadmium Toxicity

International Journal of Environmental Research and Public Health
Giuseppe GenchiAlessia Catalano
May 30, 2020

Electrogenetic cellular insulin release for real-time glycemic control in type 1 diabetic mice

Krzysztof KrawczykMartin Fussenegger
September 16, 2020

Engineering a synthesis-friendly constitutive promoter for mammalian cell expression

ACS Synthetic Biology
Chee Ka Candice Lam, Kevin Truong
July 8, 2020
Open Access

Evolutionary-driven C-MYC gene expression in mammalian fibroblasts

Scientific Reports
Marcelo T MouraMarcos A L Oliveira
June 20, 2020
Open Access

RNAi-mediated control of CRISPR functions

Xinbo HuangYuchen Liu

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