Mast Cell Signaling

Understanding the magnitude and the complexity of mast cell signaling is necessary to identify the mechanisms underlying the potential effector and regulatory roles of mast cells in the biology and pathology of those disease settings in which mast cells are activated. Here is the latest research. 

March 17, 2020

Obtaining Cancer Stem Cell Spheres from Gynecological and Breast Cancer Tumors

Journal of Visualized Experiments : JoVE
Mafalda LaranjoMaria Filomena Botelho
February 7, 2020

Gabapentin attenuates intestinal inflammation: Role of PPAR-gamma receptor

European Journal of Pharmacology
Tarcisio Vieira de BritoAndré Luiz Dos Reis Barbosa
June 23, 2020
Open Access

Hapln1b organizes the ECM to modulate kit signaling and control developmental hematopoiesis in zebrafish

BioRxiv : the Preprint Server for Biology
Christopher MahonyJ. Bertrand
January 23, 2020

Eosinophil and mast cell Siglecs: From biology to drug target

Journal of Leukocyte Biology
Jeremy A O'SullivanBruce S Bochner
January 28, 2020

Effect of H4R Antagonist N-(2-Aminoethyl)-5-Chloro-1H-Indole-2-Carboxamide (Compound A) in a Mouse Model of Allergic Asthma

Immunological Investigations
Gomathi Nagarajan, Elden Berla Thangam
April 4, 2020
Open Access

KIT ligand protects against both light-induced and genetic photoreceptor degeneration

Huirong LiLing Hou
September 16, 2020
Open Access

Modification of Neurosurgical Practice during Corona Pandemic: Our Experience at AIIMS Patna And Long Term Guidelines

Interdisciplinary Neurosurgery : Advanced Techniques and Case Management
K Singh SarajC Jha Vikas
July 28, 2020
Open Access

The Role of Inflammation and Inflammasome in Myeloproliferative Disease

Journal of Clinical Medicine
Lucia LonghitanoGiuseppe Alberto Palumbo
April 25, 2020

The impact of acute stress disorder on gallbladder interstitial cells of Cajal

Journal of Cellular Physiology
Zhen-Peng HuangBao-Ping Yu
February 9, 2020

Activation of Siglec-7 results in inhibition of in vitro and in vivo growth of human mast cell leukemia cells

Pharmacological Research : the Official Journal of the Italian Pharmacological Society
Nadine LandolinaFrancesca Levi-Schaffer
March 11, 2020

Tyrosine kinase inhibitors modulate dendritic cell activity via confining c-Kit signaling and tryptophan metabolism

International Immunopharmacology
Ching-Liang ChuRen-In You
May 4, 2020

CDP-diacylglycerol, a critical intermediate in lipid metabolism

Chemistry and Physics of Lipids
William Jennings, Richard M Epand
July 1, 2020

Gastrointestinal Stromal Tumor: Challenges and Opportunities for a New Decade

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
César Serrano, Suzanne George
March 13, 2020
Open Access

Tumor-derived exosomes in the regulation of macrophage polarization

Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]
Mirza S BaigKishore K Wary

Sign up to follow this feed and discover related papers.

Related Feeds

Antibodies: Agglutination

Antibody-mediated agglutination is the clumping of cells in the presence of antibody, which binds multiple cells together. This enhances the clearance of pathogens. Find the latest research on antibody-mediated agglutination here.

Antibodies: Complement Activation

The complement system can be activated by antigen-associated antibody. In the classical pathway of complement activation, C1q, C4b, and C3b are all able to bind to the Fc portion of IgG or IgM. Find the latest research on antibodies and complement activation here.

Antibody Development

Development of antibodies require integration of knowledge with respect to target antigen properties, antibody design criteria such as affinity, isotype selection, Fc domain engineering, and antibody cross-reactivity across species from the early stages of antibody development. Here is the latest research.

Antibody Specificity

Antibodies produced by B cells are highly specific for antigen as a result of random gene recombination and somatic hypermutation and affinity maturation. As the main effector of the humoral immune system, antibodies can neutralize foreign cells. Find the latest research on antibody specificity here.

Antibody synthesis

Antibodies have various functions including neutralization of pathogens, tumor targeting, as well as its utility in biomedical research. Here is the latest research on antibody synthesis.

Antibody-Dependent Cell Cytotoxicity

Antibody-dependent cellular toxicity refers to the lysis of a target cell by a non-sensitized effector cell of the immune system as a result of antibodies binding to the target cell membrane and engaging the Fc receptors on the immune effector cells. Find the latest research on antibody-dependent cellular toxicity here.

Antibody-Dependent Enhancement

Antibody-dependent enhancement of viral infection is the entry of virus into host cells mediated by antiviral antibodies interacting with Fc or complement receptors. This has been most extensively observed with the dengue virus. Find the latest research on antibody-dependent enhancement here.

Antigenic Modulation

Antigenic modulation occurs when an antibody cross-links antigens on a cell surface, causing the antigens to become internalized. This can lead to therapeutic failure of monoclonal antibodies as the expression of the antigen becomes decreased on target cells. Find the latest research on antigenic modulation here.

B cell Activation

B cell activation is initiated by the ligation of the B cell receptor with antigen and ultimately results in the production of protective antibodies against potentially pathogenic invaders. Here is the latest research.

B cell Differentiation

Depending on the signal received through the B cell receptor and other receptors, B cells differentiate into follicular or marginal zone B cells. Here is the latest research pertaining to this differentiation process.

© 2020 Meta ULC. All rights reserved