Mechanisms of Axon Degeneration

The mechanism of axonal degeneration is still poorly understood, but studies in animal models have suggested some cellular and molecular mechanisms responsible. The degeneration of axons in the CNS has been found to be characteristic of many neurodegenerative diseases. Discover the latest research on the mechanisms of axon degeneration here.

May 20, 2020

Mitochondrial lipid profiling data of a traumatic optic neuropathy model

Data in Brief
Ronaldo NuesiSanjoy K Bhattacharya
February 6, 2020

Lipidomics dataset of sonication-induced traumatic optic neuropathy in mice

Data in Brief
Ronaldo NuesiSanjoy K Bhattacharya
March 28, 2020

Investigating the synergic effects of valproic acid and crocin on BDNF and GDNF expression in epidermal neural crest stem cells

Acta Neurobiologiae Experimentalis
Zahra BaharvandSareh Pandamooz
April 16, 2020
Open Access

Cerebrospinal Fluid Neurofilament Light Chain Is Associated with Kynurenine Pathway Metabolite Changes in Multiple Sclerosis

International Journal of Molecular Sciences
Cecilia RajdaLászló Vécsei
March 17, 2020
Open Access

Systems Genetics of Optic Nerve Axon Necrosis During Glaucoma

Frontiers in Genetics
Andrew B StiemkeMonica M Jablonski
February 1, 2020
Open Access

Systemic loss of Sarm1 protects Schwann cells from chemotoxicity by delaying axon degeneration

Communications Biology
Weili TianHernán López-Schier
April 2, 2020
Case ReportOpen Access

Compassionate Use of the ROCK Inhibitor Fasudil in Three Patients With Amyotrophic Lateral Sclerosis

Frontiers in Neurology
Jan Christoph KochPaul Lingor
February 29, 2020
ReviewOpen Access

Axons Matter: The Promise of Treating Neurodegenerative Disorders by Targeting SARM1-Mediated Axonal Degeneration

Trends in Pharmacological Sciences
Raul KraussRobert O Hughes
February 23, 2020
Review

Regulation and signaling of the GPR17 receptor in oligodendroglial cells

Glia
Davide LeccaMarta Fumagalli

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