Mechanisms of CYP450

Cytochrome P450 (CYP450) are a family of enzymes involved in two major processes, such as the synthesis of fatty acids, steroids, and biles acids, and the metabolism of toxins and drugs. Discover the latest research on the Mechanisms of CYP450 enzymes here.

September 21, 2021

Engineering Sequence and Selectivity of Late-Stage C-H Oxidation in the MycG Iterative Cytochrome P450.

Journal of Industrial Microbiology & Biotechnology
Yohei IizakaYojiro Anzai
September 21, 2021

Cypermethrin triggers YY1-mediated testosterone biosynthesis suppression.

Ecotoxicology and Environmental Safety
Changjiang LiuLianbing Li
September 20, 2021

Harnessing P450 enzyme for biotechnology and synthetic biology.

Chembiochem : a European Journal of Chemical Biology
Qian Wang, Libo Zhang
September 20, 2021

Time-dependent inhibition of CYP3A4-mediated midazolam metabolism by macrolide antibiotics in CYP3A4 genetic variants: Comparison with testosterone metabolism.

International Journal of Clinical Pharmacology and Therapeutics
Takeshi AkiyoshiHisakazu Ohtani
September 20, 2021

Transcriptome analysis of sesame-Macrophomina phaseolina interactions revealing the distinct genetic components for early defense responses.

Physiology and Molecular Biology of Plants : an International Journal of Functional Plant Biology
Nidhi RadadiyaMahesh Kumar Mahatma
September 20, 2021
Review

A review on environmental occurrence, toxicity and microbial degradation of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs).

Journal of Environmental Management
Aishwarya RastogiMakarand M Ghangrekar
September 19, 2021

Integrative effects based on behavior, physiology and gene expression of tritiated water on zebrafish.

Ecotoxicology and Environmental Safety
Shengri LiYu Tu
September 18, 2021

Categorising high-cost high-need children and young people.

Archives of Disease in Childhood
Nikita PunjabiDougal Hargreaves
September 17, 2021
Preprint
Open Access

Comparison of children and young people admitted with SARS-CoV-2 across the UK in the first and second pandemic waves: prospective multicentre observational cohort study

MedRxiv : the Preprint Server for Health Sciences
S. V. Swann ISARIC4C Investigators
September 17, 2021

Origin of Site Selectivity in Toluene Hydroxylation by Cytochrome P450 Enzymes.

The Journal of Organic Chemistry
Xuan WuYong Liang
September 17, 2021

Overcoming the Pregnane X Receptor Liability: Rational Design to Eliminate PXR-Mediated CYP Induction.

ACS Medicinal Chemistry Letters
Joshi M RamanjuluRobert W Marquis
September 17, 2021
Correction
Open Access

Author Correction: Cytochrome P450-epoxygenated fatty acids inhibit Müller glial inflammation.

Scientific Reports
Cayla D OntkoJohn S Penn
September 17, 2021
Open Access

Efficient production of vindoline from tabersonine by metabolically engineered Saccharomyces cerevisiae.

Communications Biology
Tengfei LiuJiazhang Lian
September 17, 2021

The cytochrome P450 CYP325A is a major driver of pyrethroid resistance in the major malaria vector Anopheles funestus in Central Africa.

Insect Biochemistry and Molecular Biology
Amelie N R WambaCharles S Wondji

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