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Mechanisms of Prion Propagation

Mechanisms of Prion Propagation diagram by Public Domain, Wikimedia
Public Domain, Wikimedia

Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Whilst some key players seem to have been identified so far, the mechanisms that underlie prion propagation to the brain are still not fully understood. Here is the latest research pertaining to mechanisms of prion propagation.

Top 20 most recent papers
April 15, 2020

Short disordered protein segment regulates cross-species transmission of a yeast prion

Nature Chemical Biology
Toshinobu ShidaMotomasa Tanaka
September 24, 2019
Review

Targeting BDNF signaling by natural products: Novel synaptic repair therapeutics for neurodegeneration and behavior disorders

Pharmacological Research : the Official Journal of the Italian Pharmacological Society
Sweta BawariSamira Shirooie
May 11, 2020
Review

Prions: Roles in Development and Adaptive Evolution

Journal of Molecular Evolution
Jamie D Dixson, Rajeev K Azad
May 7, 2020

The dual role of c-src in cell-to-cell transmission of α-synuclein

EMBO Reports
Yu Ree ChoiSang Myun Park
November 9, 2019

Prion-like propagation of α-synuclein in neurodegenerative diseases

Progress in Molecular Biology and Translational Science
Airi Tarutani, Masato Hasegawa
August 23, 2019
Open Access

Transient multimers modulate conformer abundances of prion protein monomer through conformational selection

Scientific Reports
Guillaume Van der RestFrédéric Halgand
April 17, 2020

LRP1 is a master regulator of tau uptake and spread

Nature
Jennifer N RauchKenneth S Kosik
July 28, 2019

New therapeutic approaches to target alpha-synuclein in Parkinson's disease: The role of immunotherapy

International Review of Neurobiology
T Fernández-ValleJ C Gómez-Esteban
December 11, 2019
Open Access

Use of different RT-QuIC substrates for detecting CWD prions in the brain of Norwegian cervids

Scientific Reports
Edoardo BistaffaFabio Moda
April 29, 2020

Pachymeter Use and Disinfection Practice in the United Kingdom (UK): A National Survey

Journal of Glaucoma
Kirti M JasaniArchana Bhargava
October 18, 2019
ReviewOpen Access

Prion Protein in Glioblastoma Multiforme

International Journal of Molecular Sciences
Larisa RyskalinFrancesco Fornai
January 11, 2020
Open Access

Porcine Prion Protein as a Paradigm of Limited Susceptibility to Prion Strain Propagation

The Journal of Infectious Diseases
Juan Carlos EspinosaJuan María Torres
December 20, 2019
ReviewOpen Access

Reviewing the risk of feed as a vehicle for swine pathogen transmission

Veterinary Medicine and Science
Cassandra K JonesChad B Paulk
November 14, 2019

Bioluminescence Imaging of Neuroinflammation in a Mouse Model of Parkinson's Disease

Methods in Molecular Biology
Maria Eugenia Bernis, Gültekin Tamgüney

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