Metabolic Pathways & Drug Resistance

Metabolic pathways have been used as drug targets in the development of therapeutic compounds. Change of metabolic pathways can render the loss of therapeutic effects, a mechanism that is commonly found in drug resistance. Discover the latest research on metabolic pathways and drug resistance here.

July 9, 2020
Open Access

Genome-Scale Metabolic Model Driven Design of a Defined Medium for Campylobacter jejuni M1cam

Frontiers in Microbiology
Noemi TejeraDipali Singh
July 1, 2020

Structural basis for the broad substrate specificity of two acyl-CoA dehydrogenases FadE5 from mycobacteria

Proceedings of the National Academy of Sciences of the United States of America
Xiaobo ChenZihe Rao
July 4, 2020
Open Access

Development of Population-Specific Prediction Equations for Bioelectrical Impedance Analyses in Vietnamese Children

The British Journal of Nutrition
Phuong Hong NguyenDaniel J Hoffman
July 1, 2020
Open Access

Epigenetic regulation of differentially expressed Drug-metabolizing enzymes in cancer

Drug Metabolism and Disposition : the Biological Fate of Chemicals
Jiaqi WangSu Zeng
July 1, 2020

MADS-box factor AGL16 negatively regulates drought resistance via stomatal density and stomatal movement

Journal of Experimental Botany
Ping-Xia ZhaoCheng-Bin Xiang
July 6, 2020

Next-Generation Sequencing of CYP2C19 in Stent Thrombosis: Implications for Clopidogrel Pharmacogenomics

Cardiovascular Drugs and Therapy
Joel A Morales-RosadoNaveen L Pereira
June 27, 2020
Open Access

Molecular Bases of Drug Resistance in Hepatocellular Carcinoma

Jose J G MarinOscar Briz
July 8, 2020

Tetrazoles as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies

Bioorganic & Medicinal Chemistry
Neha DhimanVikas Jaitak
July 3, 2020
Open Access

Senescent cell death as an aging resistance mechanism in naked mole-rat

BioRxiv : the Preprint Server for Biology
Y. KawamuraKyoko Miura
July 8, 2020
Open Access

Differential Dynamics of the Ruminal Microbiome of Jersey Cows in a Heat Stress Environment

Animals : an Open Access Journal From MDPI
Dong-Hyeon KimEun-Tae Kim
July 7, 2020
Open Access

Metabolic fate of human immunoactive sterols in Mycobacterium tuberculosis

BioRxiv : the Preprint Server for Biology
T. VaraksaNatallia Strushkevich
June 27, 2020
Open Access

The Role of Mitochondrial Dynamics and Mitophagy in Carcinogenesis, Metastasis and Therapy

Frontiers in Cell and Developmental Biology
Yigang WangCong Yi
July 1, 2020

Hypoxic tumor microenvironment: Implications for cancer therapy

Experimental Biology and Medicine
Sukanya RoySanjukta Chakraborty

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