Metabolic Pathways & Drug Resistance

Metabolic pathways have been used as drug targets in the development of therapeutic compounds. Change of metabolic pathways can render the loss of therapeutic effects, a mechanism that is commonly found in drug resistance. Discover the latest research on metabolic pathways and drug resistance here.

October 19, 2020
Open Access

TNAP as a therapeutic target for cardiovascular calcification - a discussion of its pleiotropic functions in the body

Cardiovascular Research
Goettsch ClaudiaMagne David
October 14, 2020
Open Access

Transcriptome analysis identified long non-coding RNAs involved in the adaption of yak to high-altitude environments

Royal Society Open Science
Jin-Wei XinQiu-Mei Ji
October 25, 2020

The miR-30a-5p/CLCF1 axis regulates sorafenib resistance and aerobic glycolysis in hepatocellular carcinoma

Cell Death & Disease
Zhongqiang ZhangJing-Shan Tong
October 23, 2020
Preprint
Open Access

Agrobacterium Tumefaciens-mediated T-DNA Insertional Mutagenesis of Fusarium Oxysporum

ResearchSquare
Zeqing FengLi Wang
October 14, 2020
Open Access

Discovery of FNDR-20123, a histone deacetylase inhibitor for the treatment of Plasmodium falciparum malaria

Malaria Journal
Vijay PotluriShridhar Narayanan
October 25, 2020

Lactate-induced MRP1 expression contributes to metabolism-based etoposide resistance in non-small cell lung cancer cells

Cell Communication and Signaling : CCS
Qi DongZhihao Wu
October 19, 2020
Open Access

AMPK activation primes cytoplasmic translocation and autophagic degradation of the BCR-ABL protein in CML cells

Cancer Science
Daisuke KoyamaYusuke Furukawa
October 15, 2020
Open Access

Genetic variation associated with PPO-inhibiting herbicide tolerance in sorghum

PloS One
Pragya AdhikariTiffany M Jamann
October 19, 2020
Review
Open Access

The functions and clinical significance of circRNAs in hematological malignancies

Journal of Hematology & Oncology
Xiangxiang ZhouXin Wang
October 23, 2020
Open Access

The Fragile X Mental Retardation Protein regulates RIP1K and colorectal cancer resistance to necroptosis

Cellular and Molecular Gastroenterology and Hepatology
Antonio Di GraziaIvan Monteleone
October 23, 2020

Targeting Hypoxia Using Evofosfamide and Companion Hypoxia Imaging of FMISO-PET in Advanced Biliary Tract Cancer

Cancer Research and Treatment : Official Journal of Korean Cancer Association
Jeesun YoonDo-Youn Oh

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