Metabolite Signals in Aging

Aging leads to the loss of cellular homeostasis, a decline in physiological function and an increase on pathological substrates. Some of these substrates may include metabolites that may accumulate in tissues and disrupt normal functioning. Discover the latest research on metabolite signals in aging here.

January 15, 2022

Molecular Mechanism of -Acute Sarcopenia in Elderly Patient with COVID - 19.

Acta Medica Indonesiana
I Gusti Putu Suka AryanaSandra Surya Rini
January 15, 2022

SRT1720 induces SIRT1-independent cell death in adult T-cell leukemia/lymphoma.

The FEBS Journal
Tomohiro KozakoShin-Ichiro Honda
January 15, 2022
Review

A systematic review: metabolomics-based identification of altered metabolites and pathways in the skin caused by internal and external factors.

Experimental Dermatology
Viktor MasutinSimone Schmitz-Spanke
January 14, 2022

Biomarker-Driven Analysis Using High-Throughput Approaches in Neuroinflammation and Neurodegenerative Diseases.

Advances in Experimental Medicine and Biology
Marios G Krokidis
January 13, 2022
Review

Phosphorylated tau as a toxic agent in synaptic mitochondria: implications in aging and Alzheimer's disease.

Neural Regeneration Research
Angie K TorresCheril Tapia-Rojas
January 13, 2022

The metabolome as a biomarker of aging in Drosophila melanogaster.

Aging Cell
Xiaqing ZhaoDaniel E L Promislow
January 12, 2022
Open Access

Metabolic Rewiring by Human Placenta-Derived Mesenchymal Stem Cell Therapy Promotes Rejuvenation in Aged Female Rats.

International Journal of Molecular Sciences
Kyeoung-Hwa Kim, Kyung-Ah Lee
January 12, 2022
Review

Role of circulating molecules in age-related cardiovascular and metabolic disorders.

Inflammation and Regeneration
Yung Ting HsiaoTohru Minamino
January 12, 2022
Review

Chromatin basis of the senescence-associated secretory phenotype.

Trends in Cell Biology
Xue HaoRugang Zhang
January 12, 2022

Grainyhead 1 acts as a drug-inducible conserved transcriptional regulator linked to insulin signaling and lifespan.

Nature Communications
Giovanna GrigolonFabian Fischer
January 12, 2022
Review

Targeting Cellular Senescence with Senotherapeutics: Senolytics and Senomorphics.

The FEBS Journal
Lei ZhangPaul D Robbins
January 12, 2022

Reduced Levels of NAD in Skeletal Muscle and Increased Physiologic Frailty Are Associated With Viral Coinfection in Asymptomatic Middle-Aged Adults.

Journal of Acquired Immune Deficiency Syndromes : JAIDS
Thanh TranMonty Montano
January 11, 2022

Minimally invasive skin sampling and transcriptome analysis using microneedles for skin type biomarker research.

Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
Seo Hyeong KimKwang Hoon Lee
January 8, 2022

Lipopolysaccharide Induces Gliotoxicity in Hippocampal Astrocytes from Aged Rats: Insights About the Glioprotective Roles of Resveratrol.

Molecular Neurobiology
Larissa Daniele BoberminAndré Quincozes-Santos

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