Metabolite Signals in Aging

Aging leads to the loss of cellular homeostasis, a decline in physiological function and an increase on pathological substrates. Some of these substrates may include metabolites that may accumulate in tissues and disrupt normal functioning. Discover the latest research on metabolite signals in aging here.

July 2, 2020
Open Access

Surtuin 1 as a potential prognostic biomarker in very elderly patients with colorectal cancer

The Korean Journal of Internal Medicine
Guk Jin LeeIn Sook Woo
July 7, 2020

Anti-aging Klotho Protects SH-SY5Y Cells Against Amyloid β1-42 Neurotoxicity: Involvement of Wnt1/pCREB/Nrf2/HO-1 Signaling

Journal of Molecular Neuroscience : MN
Mohsen SedighiMehrdad Roghani
July 11, 2020
Open Access

Characteristic Metabolic Changes of the Crust from Dry-Aged Beef Using 2D NMR Spectroscopy

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Hyun Cheol KimCheorun Jo
July 6, 2020
Open Access

HEBE, a novel positive regulator of senescence in Solanum lycopersicum

Scientific Reports
Sara ForlaniChiara Mizzotti
July 1, 2020
Open Access

Biotransformation of Selenium by Lactic Acid Bacteria: Formation of Seleno-Nanoparticles and Seleno-Amino Acids

Frontiers in Bioengineering and Biotechnology
Fernando Gabriel MartínezFernanda Mozzi
June 24, 2020

Age-related epigenetic drift deregulates SIRT6 expression and affects its downstream genes in human peripheral blood mononuclear cells

Epigenetics : Official Journal of the DNA Methylation Society
Magdalena OwczarzMonika Puzianowska-Kuźnicka
July 6, 2020
Preprint
Open Access

Metabolomics and lipidomics in C. elegans using a single sample preparation

BioRxiv : the Preprint Server for Biology
M. MolenaarsRiekelt H Houtkooper
June 24, 2020

The effects and mechanism of caloric restriction on energy metabolism

Sheng li xue bao : [Acta physiologica Sinica]
Xiao-Na FanGe-Yang Xu
July 2, 2020
Review
Open Access

Mitochondrial Dysfunction and Inflammaging in Heart Failure: Novel Roles of CYP-Derived Epoxylipids

Cells
Hedieh Keshavarz-BahaghighatJohn M Seubert
June 28, 2020

Whole body deletion of Gpr68 does not change hematopoietic stem cell function

Stem Cell Research
Xiaofei HeJing Fang
July 3, 2020

Osteosarcopenia in reproductive-aged women with polycystic ovary syndrome: a multicenter case-control study

The Journal of Clinical Endocrinology and Metabolism
Maryam KazemiMarla E Lujan
July 8, 2020
Open Access

The Protective Effect of Chlorogenic Acid on Vascular Senescence via the Nrf2/HO-1 Pathway

International Journal of Molecular Sciences
Yoshiko HadaJun Wada
July 1, 2020
Review
Open Access

Implications of NAD+ boosters in translational medicine

European Journal of Clinical Investigation
Baeki E KangDongryeol Ryu
June 27, 2020
Open Access

Sedentary and Trained Older Men Have Distinct Circulating Exosomal microRNA Profiles at Baseline and in Response to Acute Exercise

Frontiers in Physiology
Venugopalan D NairStuart C Sealfon
July 6, 2020

CRISPR/Cas9-mediated Knockout of SIRT6 Imparts Remarkable Anti-proliferative Response in Human Melanoma Cells in vitro and in vivo

Photochemistry and Photobiology
Liz M Garcia-PetersonNihal Ahmad
June 24, 2020
Open Access

Effects of Rich in Β-Glucans Edible Mushrooms on Aging Gut Microbiota Characteristics: An In Vitro Study

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Evdokia K MitsouAdamantini Kyriacou
June 25, 2020

Untargeted metabolomics for uncovering biological markers of human skeletal muscle ageing

Aging
Daniel J WilkinsonPhilip J Atherton

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