Metabolite Signals in Aging

Aging leads to the loss of cellular homeostasis, a decline in physiological function and an increase on pathological substrates. Some of these substrates may include metabolites that may accumulate in tissues and disrupt normal functioning. Discover the latest research on metabolite signals in aging here.

January 15, 2021
Review
Open Access

Mono(ADP-ribosyl)ation Enzymes and NAD+ Metabolism: A Focus on Diseases and Therapeutic Perspectives

Cells
Palmiro PoltronieriLuca Palazzo
January 9, 2021
Open Access

Metabolomic signatures of the long-term exposure to air pollution and temperature

Environmental Health : a Global Access Science Source
Feiby L NassanJoel D Schwartz
January 5, 2021
Open Access

The Discovery of Druggable Anti-aging Agents

Annals of Geriatric Medicine and Research
Gulperi Yalcin, Cheol-Koo Lee
January 7, 2021
Open Access

Short-term NAD+ supplementation prevents hearing loss in mouse models of Cockayne syndrome

Npj Aging and Mechanisms of Disease
Mustafa N OkurVilhelm A Bohr
January 12, 2021

Plasma metabolites associated with chronic kidney disease and renal function in adults from the Baltimore Longitudinal Study of Aging

Metabolomics : Official Journal of the Metabolomic Society
Yuko YamaguchiRichard D Semba
January 9, 2021

Effects of Chronic Photobiomodulation with Transcranial Near-Infrared Laser on Brain Metabolomics of Young and Aged Rats

Molecular Neurobiology
Fabrízio Dos Santos CardosoSérgio Gomes da Silva
January 16, 2021
Review
Open Access

Control of Mesenchymal Stromal Cell Senescence by Tryptophan Metabolites

International Journal of Molecular Sciences
Kenneth K Wu
January 16, 2021
Open Access

The Effect of Tryptophan 2,3-Dioxygenase Inhibition on Kynurenine Metabolism and Cognitive Function in the APP23 Mouse Model of Alzheimer's Disease

International Journal of Tryptophan Research : IJTR
Fjh SorgdragerP P De Deyn
January 7, 2021
Open Access

Choline Acetyltransferase Induces the Functional Regeneration of the Salivary Gland in Aging SAMP1/Kl -/- Mice

International Journal of Molecular Sciences
Nguyen Khanh ToanSang-Gun Ahn
January 16, 2021

The longevity gene Klotho and its CSF protein profiles as modifier for Parkinson´s disease

European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies
Milan ZimmermannKathrin Brockmann
January 9, 2021
Review
Open Access

Role of Sirtuins in Modulating Neurodegeneration of the Enteric Nervous System and Central Nervous System

Frontiers in Neuroscience
Pavithra ChandramowlishwaranShanthi Srinivasan
January 5, 2021
Open Access

Effects of Aging on Angiogenic and Muscle Growth-Related Factors in Naturally Aged Rat Skeletal Muscles

Annals of Geriatric Medicine and Research
Hyo-Seong YeoNa-Young Ahn
January 15, 2021
Open Access

Sirtuin 6 is a regulator of dendrite morphogenesis in rat hippocampal neurons

Neurochemistry International
Hitomi MatsunoKazuhiro Sohya
January 15, 2021
Open Access

Moderate Exercise Inhibits Age-Related Inflammation, Liver Steatosis, Senescence, and Tumorigenesis

The Journal of Immunology : Official Journal of the American Association of Immunologists
Arianna BianchiCaroline L Wilson
January 17, 2021
Open Access

Targeted metabolomics analysis of postoperative delirium

Scientific Reports
Bridget A TrippHasan H Otu
January 16, 2021
Open Access

Apremilast prevents IL‑17‑induced cellular senescence in ATDC5 chondrocytes mediated by SIRT1

International Journal of Molecular Medicine
Benlong WangFeng Li

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