Microglia & CNS Diseases

Microglia are resident macrophages of the CNS. They play a role in scavenging the CNS for plaques, phagocytosis, and extracellular signaling. Here is the latest research on their role in CNS diseases.

January 21, 2022

Dimethyl Fumarate Reduces Inflammation in Chronic Active Multiple Sclerosis Lesions.

Neurology. Neuroimmunology and Neuroinflammation
Nicole ZingerSusan A Gauthier
January 21, 2022
Open Access

Astrocyte-Derived Pleiotrophin Mitigates Late-Stage Autoimmune CNS Inflammation.

Frontiers in Immunology
Mathias LinnerbauerVeit Rothhammer
January 21, 2022

Sex-specific transcriptome of spinal microglia in neuropathic pain due to peripheral nerve injury.

Glia
Nathan T FioreGila Moalem-Taylor
January 20, 2022

Pharmacological inhibition of UPR sensor PERK attenuates HIV Tat-induced inflammatory M1 phenotype in microglial cells.

Cell Biochemistry and Function
Douglas Bardini SilveiraAguinaldo Roberto Pinto
January 20, 2022

Neuroinflammation: The role of anthocyanins as neuroprotectants.

Current Neuropharmacology
Otilia J F BanjiSaeed Alshaharani
January 20, 2022

Microglia activate early anti-viral responses upon HSV-1 entry into the brain to counteract development of encephalitis-like disease in mice.

Journal of Virology
Georgios Katzilieris-PetrasSøren R Paludan
January 19, 2022

Specific Silencing of Microglial Gene Expression in the Rat Brain by Nanoparticle-Based Small Interfering RNA Delivery.

ACS Applied Materials & Interfaces
Shanshan GuoChun-Xia Yi
January 19, 2022
Review

Soluble TREM2: Innocent bystander or active player in neurological diseases?

Neurobiology of Disease
Fabia FilipelloLaura Piccio
January 19, 2022

Minor terpenoids from the stems and twigs of Rhododendron ovatum.

Journal of Asian Natural Products Research
Min MaShi-Shan Yu
January 19, 2022
Review

Progranulin as a therapeutic target in neurodegenerative diseases.

Trends in Pharmacological Sciences
Herve RhinnArnon Rosenthal
January 19, 2022
Review

Microglia in CNS infections: insights from Toxoplasma gondii and other pathogens.

Trends in Parasitology
Maureen N CowanTajie H Harris
January 19, 2022

Macrophage Nuclear Receptor Corepressor 1 Deficiency Protects Against Ischemic Stroke in Mice.

Journal of Cardiovascular Translational Research
Shuai ShaoSheng-Zhong Duan
January 17, 2022
Preprint
Open Access

Glycation renders alpha-synuclein oligomeric strain and modulates microglia activation

BioRxiv : the Preprint Server for Biology
M. KumariTushar Kanti Maiti
January 17, 2022
Review

T cells, α-synuclein and Parkinson disease.

Handbook of Clinical Neurology
Francesca GarrettiDavid Sulzer
January 16, 2022
Preprint
Open Access

Integrative in situ mapping of single-cell transcriptional states and tissue histopathology in an Alzheimer's disease model

BioRxiv : the Preprint Server for Biology
H. ZengXiao Wang
January 16, 2022

A kinetic scheme to examine the role of glial cells in the pathogenesis of Alzheimer's disease.

Metabolic Brain Disease
R A Thuraisingham

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