Feed Preview

Misfolded Proteins: ND

Misfolded Proteins: ND diagram by

Protein misfolding is the primary cause of several neurodegenerative disease, including Alzheimer’s and Parkinson’s disease. Here is the latest research.

Top 20 most recent papers
Journal of Alzheimer's Disease : JAD

Effect Modifiers of TDP-43 Associated Hippocampal Atrophy Rates in Patients with Alzheimer's Disease Neuropathological Changes

Journal of Alzheimer's Disease : JADJanuary 14, 2020
Marina BuciucKeith A Josephs
NeuroImage

Correlative x-ray phase-contrast tomography and histology of human brain tissue affected by Alzheimer's disease

NeuroImageJanuary 15, 2020
Mareike TöpperwienTim Salditt
2
bioRxiv

Stromal Amyloid β drives Neutrophil extracellular trap formation to augment tumour growth

bioRxivJanuary 11, 2020
Hafsa MunirJacqueline D Shields
12
bioRxiv

A molecular mechanism by which amyloid-β induces transcriptional inactivation of CREB in Alzheimer's Disease

bioRxivJanuary 9, 2020
Katarzyna M. GrochowskaMichael R. Kreutz
9
Journal of Molecular Biology

Autophagy in astrocytes and its implications in neurodegeneration

Journal of Molecular BiologyJanuary 14, 2020
Katherine Sung, Maria Jimenez-Sanchez
26
Neurobiology of Disease

Every-other-day feeding exacerbates inflammation and neuronal deficits in 5XFAD mouse model of Alzheimer's disease

Neurobiology of DiseaseJanuary 14, 2020
Divna LazicMilka Perovic
8
Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry

Exploring the Multi-Target Performance of Mitochondriotropic Antioxidants against the Pivotal Alzheimer's Disease Pathophysiological Hallmarks

Molecules : a Journal of Synthetic Chemistry and Natural Product ChemistryJanuary 16, 2020
Sofia BenfeitoFernanda Borges
Advances in Protein Chemistry and Structural Biology

The intrinsic and extrinsic factors that contribute to proteostasis decline and pathological protein misfolding

Advances in Protein Chemistry and Structural BiologyJanuary 14, 2020
Elise A Kikis
1
Advances in Protein Chemistry and Structural Biology

LOXL1 folding in exfoliation glaucoma

Advances in Protein Chemistry and Structural BiologyJanuary 14, 2020
Audrey M BernsteinJ Mario Wolosin
PloS One

Alterations of aqueous humor Aβ levels in Aβ-infused and transgenic mouse models of Alzheimer disease

PloS OneJanuary 11, 2020
Da Eun KwakYoungSoo Kim
1
Analytical Chemistry

Real-Time Monitoring of Self-Aggregation of β-Amyloid by a Fluorescent Probe based on Ruthenium Complex

Analytical ChemistryJanuary 17, 2020
Hui-Juan YuLin Yu
bioRxiv

C subunit of the ATP synthase is an amyloidogenic channel-forming peptide: possible implications in mitochondrial pathogenesis

bioRxivJanuary 16, 2020
Giuseppe Federico AmodeoEvgeny V Pavlov
Advances in Protein Chemistry and Structural Biology

Liquid-liquid phase transitions and amyloid aggregation in proteins related to cancer and neurodegenerative diseases

Advances in Protein Chemistry and Structural BiologyJanuary 14, 2020
Guilherme A P de OliveiraTuane C R G Vieira
12
4
Annals of Translational Medicine

Genome-wide association study of cerebrospinal fluid neurofilament light levels in non-demented elders

Annals of Translational MedicineJanuary 14, 2020
Li-Dong NiuAlzheimer’s Disease Neuroimaging Initiative
Sub-cellular Biochemistry

TRiC/CCT Chaperonin: Structure and Function

Sub-cellular BiochemistryJanuary 16, 2020
Mingliang JinYao Cong
Neuroscience Letters

Orexin-A exacerbates Alzheimer's disease by inducing mitochondrial impairment

Neuroscience LettersJanuary 14, 2020
Maoyu LiZhaohong Xie
Cellular and Molecular Neurobiology

Resveratrol Protects Optic Nerve Head Astrocytes from Oxidative Stress-Induced Cell Death by Preventing Caspase-3 Activation, Tau Dephosphorylation at Ser422 and Formation of Misfolded Protein Aggregates

Cellular and Molecular NeurobiologyJanuary 11, 2020
John C MeansPeter Koulen
Advances in Protein Chemistry and Structural Biology

Misfolded proteins as a therapeutic target in Alzheimer's disease

Advances in Protein Chemistry and Structural BiologyJanuary 14, 2020
S Imindu Liyanage, Donald F Weaver
1
Analytical Chemistry

Exploring Interactions of Aptamers with Aβ40 Amyloid Aggregates and Its Application: Detection of Amyloid Aggregates

Analytical ChemistryJanuary 10, 2020
Yan ZhengYao Xu
1
Veterinary Research

Goats naturally devoid of PrPC are resistant to scrapie

Veterinary ResearchJanuary 12, 2020
Øyvind SalvesenCecilie Ersdal
1

See more papers from this feed

Related Feeds

ALS

Amyotrophic Lateral Sclerosis (ALS), also known as motor neuron disease, is associated with the death of neurons that control voluntary muscles. Discover the latest research on ALS here.

ALS & FTD: TDP-43

ALS shares with a considerable proportion of FTD cases the same neuropathological substrate, namely, inclusions of abnormally phosphorylated protein tdp-43 (ptdp-43). Here are the latest discoveries pertaining to ptdp-43 and these diseases.

ALS - Pathogenic Mechanisms

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. Here is the latest research investigating pathogenic mechanisms that underlie this genetically heterogeneous disorder.

ALS - Phenotypes

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. Here is the latest research investigating phenotypes associated with this genetically heterogeneous disorder.

ALS: Genetics

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. ALS is a genetically heterogeneous disorder with several causative genes. Here are the latest discoveries pertaining to the genetics of this disease.

ALS: Prions

Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Prion-like mechanisms are associated with the pathogenesis of Amyotrophic Lateral Sclerosis (ALS). Here are the latest discoveries pertaining to this disease.

ALS: Stress Granules

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease characterized by cytoplasmic protein aggregates within motor neurons. TDP-43 is an ALS-linked protein that is known to regulate splicing and storage of specific mRNAs into stress granules, which have been implicated in formation of ALS protein aggregates. Here is the latest research.

ALS: Therapies

Amyotrophic Lateral Sclerosis (ALS), also known as motor neuron disease, is associated with the death of neurons that control voluntary muscles. Discover the latest research on ALS therapies here.

ALS: Transposon de-silencing

Transposon silencing is a form of transcriptional gene silencing. These gene silencing mechanisms are impaired in Amyotrophic lateral sclerosis (ALS). Here are the latest discoveries pertaining to transposon silencing and this disease.

Age-related Dementia

Age-related dementia (Alzheimer's disease) results from the destructive impact of the pulse on cerebral vasculature. Evidence is reviewed that the neuropathology of the dementia is caused by the breakdown of small cerebral vessels (silent microbleeds), that the microbleeds result from pulse-induced damage to the cerebral vessels, and that pulse becomes increasingly destructive with age, because of the age-related stiffening of the aorta and great arteries, which causes an increase in the intensity of the pressure pulse. Discover the latest research on age-related dementia here.

© 2020 Meta ULC. All rights reserved
/feed-previews/misfolded-proteins-nd/2188d755-1ef3-4cfc-8f49-f4478c3104e5