Neurodegeneration: Misfolded Proteins

Protein misfolding is the primary cause of several neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease. This feed follows studies investigating protein misfolding in neurodegeneration.

January 20, 2022
Review

Regulation of Neurodegeneration-associated Protein Fragments by the N-degron Pathways.

Neurotoxicity Research
Mohamed A EldeebRichard P Fahlman
January 20, 2022

Pharmacological inhibition of UPR sensor PERK attenuates HIV Tat-induced inflammatory M1 phenotype in microglial cells.

Cell Biochemistry and Function
Douglas Bardini SilveiraAguinaldo Roberto Pinto
January 19, 2022

Drosophila: A Model to Study the Pathogenesis of Parkinson's Disease.

CNS & Neurological Disorders Drug Targets
Rahul, Yasir Hasan Siddique
January 17, 2022

Metal Ions Bound to Prion Protein Affect its Interaction with Plasminogen Activation System.

The Protein Journal
Maryam Borumand, Vincent Ellis
January 17, 2022

Ganglioside binding domains in proteins: Physiological and pathological mechanisms.

Advances in Protein Chemistry and Structural Biology
Fodil AzzazJacques Fantini
January 16, 2022
Review

Role of systems biology and multi-omics analyses in delineating spatial interconnectivity and temporal dynamicity of ER stress mediated cellular responses.

Biochimica Et Biophysica Acta. Molecular Cell Research
Priyanka MallickSaikat Chakrabarti
January 16, 2022

The modulation of neuroinflammation by inducible nitric oxide synthase.

Journal of Cell Communication and Signaling
Alberto Fernando Oliveira Justo, Claudia Kimie Suemoto
January 14, 2022
Review

Body-first Parkinson's disease and variant Creutzfeldt-Jakob disease - similar or different?

Neurobiology of Disease
Amanda L Woerman, Gültekin Tamgüney
January 14, 2022

Braiding Braak and Braak: Staging patterns and model selection in network neurodegeneration.

Network Neuroscience
Prama PutraAlain Goriely
January 14, 2022
Review

Force Spectroscopy in Mechanical Protein Domains Unfolding.

Advances in Experimental Medicine and Biology
Dionysios G Cheirdaris
January 13, 2022
Review

Therapeutics in the Pipeline Targeting α-Synuclein for Parkinson's Disease.

Pharmacological Reviews
Hilary Grosso JasutkarM Maral Mouradian
January 12, 2022
Preprint
Open Access

The channel activities of the full-length prion and truncated proteins

BioRxiv : the Preprint Server for Biology
J. WuJinghui Luo
January 12, 2022
Open Access

Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies.

NPJ Vaccines
Changyoun KimMichael G Agadjanyan
January 12, 2022

Screening the Efficacy of Melatonin on Neurodegeneration Mediated by Endoplasmic Reticulum Stress, Inflammation, and Oxidative Damage.

Applied Biochemistry and Biotechnology
Fathima Hajee Basha, S Hemalatha
January 10, 2022
Review

An expanding repertoire of protein acylations.

Molecular & Cellular Proteomics : MCP
Yuxuan XuLi Bao
January 10, 2022

Prion-like α-synuclein pathology in the brain of infants with Krabbe disease.

Brain : a Journal of Neurology
Christopher HattonDaniel Erskine
January 9, 2022
Open Access

SOD1 mutations associated with amyotrophic lateral sclerosis analysis of variant severity.

Scientific Reports
Mariusz BerdyńskiMagdalena Kuźma-Kozakiewicz

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