Neurodegeneration: Misfolded Proteins

Protein misfolding is the primary cause of several neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease. This feed follows studies investigating protein misfolding in neurodegeneration.

December 3, 2020
Open Access

TRIM11 Prevents and Reverses Protein Aggregation and Rescues a Mouse Model of Parkinson's Disease

Cell Reports
Guixin ZhuXiaolu Yang
December 29, 2020

Molecular Dynamics Study of the Interaction between the N-terminal of α-Synuclein and a Lipid Bilayer Mimicking Synaptic Vesicles

The Journal of Physical Chemistry. B
Christopher Kang, Rui Sun
December 12, 2020
Open Access

Common Factors in Neurodegeneration: A Meta-Study Revealing Shared Patterns on a Multi-Omics Scale

Nicolas RuffiniSusanne Gerber
January 6, 2021
Open Access

Complete microglia deficiency accelerates prion disease without enhancing CNS prion accumulation

BioRxiv : the Preprint Server for Biology
B. M. BradfordNeil A Mabbott
January 5, 2021

Role of Mitochondrial Heat-shock Proteins and Immunophilins in Neuro degenerative Diseases

Current Drug Targets
Cristina Daneri-BecerraMario D Galigniana
December 15, 2020

Extracellular vesicles - propagators of neuropathology and sources of potential biomarkers and therapeutics for neurodegenerative diseases

Journal of Cell Science
Natasha VassileffAndrew F Hill
December 10, 2020

Purines and Pyrimidines: Metabolism, Function and Potential as therapeutic options in neurodegenerative diseases

Current Protein & Peptide Science
Debanjan Kundu, Vikash Kumar Dubey
December 30, 2020
Open Access

Insoluble proteins catch heterologous soluble proteins into inclusion bodies by intermolecular interaction of aggregating peptides.

Jose Vicente CarrataláNeus Ferrer-Miralles
January 5, 2021
Open Access

Development of Biological Response Modifiers Based on Unique Medicinal Chemical Strategy

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
Yuichi Hashimoto
December 8, 2020

In vivo therapeutic applications of phosphorus dendrimers: state of the art

Drug Discovery Today
Serge MignaniJean-Pierre Majoral
December 19, 2020
Open Access

Safety profile of the transcription factor EB (TFEB)-based gene therapy through intracranial injection in mice

Translational Neuroscience
Zhenyu LiJianping Lv
January 13, 2021
Open Access

Suppression of aggregate and amyloid formation by a novel intrinsically disordered region in metazoan Hsp110 chaperones

BioRxiv : the Preprint Server for Biology
Unekwu M Yakubu, Kevin A Morano
December 3, 2020
Open Access

BODIPY Dyes as Probes and Sensors to Study Amyloid-β-Related Processes

Sergei V Dzyuba
December 7, 2020
Open Access

Pharmacological intervention in a transgenic mouse model improves Alzheimer's-associated pathological phenotype: involvement of proteasome activation

Free Radical Biology & Medicine
Aleksandra N Mladenovic DjordjevicEfstathios S Gonos
January 8, 2021
Open Access

Chinese nutraceuticals and physical activity; their role in neurodegenerative tauopathies

Chinese Medicine
Abdullahi AlausaAminat Ismail

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