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Misfolding & Aggregation Diseases

Misfolding & Aggregation Diseases diagram by undefined

Misfolding and aggregation of proteins can lead to several diseases. For instance, misfolding of prion or tau proteins are associated with several neurodegenerative diseases. Here is the latest research on diseases caused by protein misfolding and aggregation.

Top 20 most recent papers

SPDI: Data Model for Variants and Applications at NCBI

BioinformaticsNovember 18, 2019
J. Bradley HolmesBrandi L. Kattman

Enzymatic degradation of RNA causes widespread protein aggregation in cell and tissue lysates

bioRxivNovember 17, 2019
Johan AarumDenise Sheer
PLoS Genetics

AMPK regulates ESCRT-dependent microautophagy of proteasomes concomitant with proteasome storage granule assembly during glucose starvation

PLoS GeneticsNovember 18, 2019
Jian-Hui LiMark Hochstrasser
Protein and Peptide Letters

VITPOR AI, A Coagulation Factor XIIa Inhibitor from Porphyra yezoensis: In Vivo Mode of Action and Assessment of Platelet Function Analysis

Protein and Peptide LettersOctober 26, 2019
Kalkooru L VenkatramanAlka Mehta
Biological Psychiatry

Propagation of Tau Pathology: Integrating Insights From Postmortem and In Vivo Studies

Biological PsychiatryOctober 3, 2019
Thomas VogelsMichael L Schöll
European Journal of Pharmacology

Epinephrine restores platelet functions inhibited by ticagrelor: A mechanistic approach

European Journal of PharmacologyNovember 15, 2019
Anne-Céline MartinChristilla Bachelot-Loza
Bioorganic Chemistry

Conjugates of tacrine and 1,2,4-thiadiazole derivatives as new potential multifunctional agents for Alzheimer's disease treatment: Synthesis, quantum-chemical characterization, molecular docking, and biological evaluation

Bioorganic ChemistryOctober 28, 2019
Galina F MakhaevaRudy J Richardson
Molecular Therapy. Nucleic Acids

Size Matters: Arginine-Derived Peptides Targeting the PSMA Receptor Can Efficiently Complex but Not Transfect siRNA

Molecular Therapy. Nucleic AcidsOctober 23, 2019
Christopher N CultraraDavid Sabatino
Frontiers in Molecular Neuroscience

Prion-Like Propagation of Protein Misfolding and Aggregation in Amyotrophic Lateral Sclerosis

Frontiers in Molecular NeuroscienceNovember 1, 2019
Luke McAlaryNeil R. Cashman
Chemical Communications : Chem Comm

Spontaneous chiral self-assembly of achiral AIEgens into AIEgen-silica hybrid nanotubes

Chemical Communications : Chem CommNovember 18, 2019
Wanning ZhangLu Han
Analytica Chimica Acta

Label-free peptide nucleic acid biosensor for visual detection of multiple strains of influenza A virus suitable for field applications

Analytica Chimica ActaNovember 19, 2019
NAVEEN KUMARVijendra Pal Singh

Anomalous dispersion of bioinspired flower-like microparticles for oil/water separation

NanotechnologyNovember 18, 2019
Chengduan YangHui-Jiuan Chen
Frontiers in Microbiology

HIV-1 Nef Targets HDAC6 to Assure Viral Production and Virus Infection

Frontiers in MicrobiologyOctober 30, 2019
Sara Marrero-HernándezAgustín Valenzuela-Fernández
Anti-cancer Agents in Medicinal Chemistry

Highly Concentrated Multifunctional Silver Nanoparticle Fabrication through Green Reduction of Silver Ions in Terms of Mechanics and Therapeutic Potentials

Anti-cancer Agents in Medicinal ChemistryOctober 21, 2019
Mohammad Ali EbrahimzadehShahram Eslami
ACS Applied Polymer Materials

Luminescent Solar Concentrators Based on Energy Transfer from an Aggregation-Induced Emitter Conjugated Polymer

ACS Applied Polymer MaterialsNovember 8, 2019
Guanpeng LyuRachel C Evans
ACS Nano

Label-Free Analysis of Protein Aggregation and Phase Behaviour

ACS NanoNovember 18, 2019
Zenon ToprakciogluTuomas P J Knowles
Biochemical and Biophysical Research Communications

Activation of tumor-promoting pathways implicated in hepatocellular adenoma/carcinoma, a long-term complication of glycogen storage disease type Ia

Biochemical and Biophysical Research CommunicationsNovember 14, 2019
Jun-Ho ChoJanice Yang Chou
Frontiers in Cell and Developmental Biology

D-Ribose Induces Podocyte NLRP3 Inflammasome Activation and Glomerular Injury via AGEs/RAGE Pathway

Frontiers in Cell and Developmental BiologyOctober 30, 2019
Jinni HongPin-Lan Li
Biochemistry and Biophysics Reports

Hypomyelinating leukodystrophy-associated mutation of RARS leads it to the lysosome, inhibiting oligodendroglial morphological differentiation

Biochemistry and Biophysics ReportsNovember 19, 2019
Naoto MatsumotoJunji Yamauchi
International Journal of Molecular Sciences

Sulfolobus acidocaldarius Microvesicles Exhibit Unusually Tight Packing Properties as Revealed by Optical Spectroscopy

International Journal of Molecular SciencesOctober 25, 2019
Alexander P BonannoParkson Lee-Gau Chong

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