Misfolding & Aggregation Diseases

Misfolding and aggregation of proteins can lead to several diseases. For instance, misfolding of prion or tau proteins are associated with several neurodegenerative diseases. Here is the latest research on diseases caused by protein misfolding and aggregation.

June 25, 2020

Dual targeting of monomeric tau and α-synuclein aggregation: A new multitarget therapeutic strategy for neurodegeneration

ACS Chemical Neuroscience
Moustafa T Gabr, Francesca Peccati
June 25, 2020
Open Access

Parkinson's disease: etiopathogenesis and treatment

Journal of Neurology, Neurosurgery, and Psychiatry
Joseph Jankovic, Eng King Tan
June 28, 2020
Open Access

Hsp70:CHIP ubiquitinates dysfunctional but not native neuronal NO synthase

Molecular Pharmacology
Amanda K DavisYoichi Osawa
June 27, 2020
Open Access

Amylin and beta amyloid proteins interact to form amorphous heterocomplexes with enhanced toxicity in neuronal cells

Scientific Reports
Prashant BharadwajPhilip Newsholme
July 2, 2020
Open Access

Insights into lncRNAs in Alzheimer's Disease Mechanisms

RNA Biology
Dingfeng LiQiang Liu
July 1, 2020
Review

Alzheimer's Disease: The Link Between Amyloid-β and Neurovascular Dysfunction

Journal of Alzheimer's Disease : JAD
Ernesto SolisErin R Hascup
July 6, 2020

Poly adenosine diphosphate-ribosylation and neurodegenerative diseases

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences
Yi Wang, Yunbi Lu
June 26, 2020
Review

Alzheimer's disease; a review of the pathophysiological basis and therapeutic interventions

Life Sciences
A A D T AbeysingheC Udawatte
July 4, 2020
Preprint

Zinc Determines Dynamical Properties and Aggregation Kinetics of Human Insulin

BioRxiv : the Preprint Server for Biology
K. PounotGiorgio Schiro
June 26, 2020
Open Access

Translation Imaging in Parkinson's Disease: Focus on Neuroinflammation

Frontiers in Aging Neuroscience
Sara BelloliMaria Carla Gilardi
June 24, 2020
Open Access

Comparative study of the stabilities of synthetic in vitro and natural ex vivo transthyretin amyloid fibrils

The Journal of Biological Chemistry
Sara RaimondiVittorio Bellotti
July 1, 2020

Large-scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease

Acta Neuropathologica
S Bandres-CigaInternational Parkinson Disease Genomics Consortium
June 26, 2020
Review
Open Access

Chaperones and Proteostasis: Role in Parkinson's Disease

Diseases
Neha JoshiShirisha Nagotu

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