Misfolding & Aggregation Diseases

Misfolding and aggregation of proteins can lead to several diseases. For instance, misfolding of prion or tau proteins are associated with several neurodegenerative diseases. Here is the latest research on diseases caused by protein misfolding and aggregation.

January 17, 2021
Preprint
Open Access

Phospholipids Uniquely Modify Secondary Structure of α-Synuclein Oligomers

BioRxiv : the Preprint Server for Biology
T. DouDmitry Kurouski
January 20, 2021

Improving the inhibition of β-amyloid aggregation by withanolide and withanoside derivatives

International Journal of Biological Macromolecules
Shreya DubeyRajagopal Subramanyam
January 19, 2021

Seeding-Competent Tau in Gray Matter Versus White Matter of Alzheimer's Disease Brain

Journal of Alzheimer's Disease : JAD
Ruozhen WuFei Liu
January 20, 2021

Facile Installation of Post-translational Modifications on the Tau Protein via Chemical Mutagenesis

ACS Chemical Neuroscience
Philip R LindstedtMichele Vendruscolo
January 22, 2021

Parkinson-like early autonomic dysfunction induced by vagal application of DOPAL in rats.

CNS Neuroscience & Therapeutics
Jie SunBai-Yan Li
January 17, 2021

Interplay between tau and α-synuclein LLPS

Protein Science : a Publication of the Protein Society
Anna SiegertMarkus Zweckstetter
January 18, 2021
Open Access

Mass spectrometry characterization of light chain fragmentation sites in cardiac AL amyloidosis: insights into the timing of proteolysis

The Journal of Biological Chemistry
Francesca LavatelliGiovanni Palladini
January 20, 2021
Review

Photoresponsive materials for intensified modulation of Alzheimer's amyloid-β protein aggregation: A review

Acta Biomaterialia
Wei LiuYan Sun
January 19, 2021
Review
Open Access

Heterotypic interactions in amyloid function and disease

The FEBS Journal
Katerina KonstantouleaJoost Schymkowitz
January 16, 2021
Open Access

Familial Alzheimer's disease mutations in amyloid protein precursor alter proteolysis by γ-secretase to increase amyloid β-peptides of >45 residues

The Journal of Biological Chemistry
Sujan DevkotaMichael S Wolfe
January 20, 2021

Caterpillar Medicinal Mushroom, Cordyceps militaris (Ascomycetes), Protects Aβ1-42-Induced Neurologic Damage in C6 Glial Cells

International Journal of Medicinal Mushrooms
Mei Tong HeEun Ju Cho
January 16, 2021

Direct Observation of β-Barrel Intermediates in the Self-Assembly of Toxic SOD128-38 and Absence in Nontoxic Glycine Mutants

Journal of Chemical Information and Modeling
Yunxiang SunFeng Ding
January 21, 2021

Current advances in plasma and cerebrospinal fluid biomarkers in Alzheimer's disease.

Current Opinion in Neurology
Antoine LeuzyOskar Hansson
January 22, 2021
Review

Retromer dysfunction at the nexus of tauopathies.

Cell Death and Differentiation
Julian M CarosiTimothy J Sargeant
January 21, 2021

Global and Regional Changes in Perivascular Space in Idiopathic and Familial Parkinson's Disease.

Movement Disorders : Official Journal of the Movement Disorder Society
Erin K DonahueFarshid Sepehrband
January 21, 2021
Preprint
Open Access

Amyloid like Aggregates Formed by the Self-Assembly of Proline and Hydroxyproline

ChemRxiv
Bharti KoshtiNidhi Gour
January 19, 2021
Preprint
Open Access

Enhancing top-down proteomics of brain tissue with FAIMS

BioRxiv : the Preprint Server for Biology
J. M. FulcherVladislav A Petyuk

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