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Misfolding & Aggregation Diseases

Misfolding & Aggregation Diseases diagram by Juan Gaertner, Shutterstock
Juan Gaertner, Shutterstock

Misfolding and aggregation of proteins can lead to several diseases. For instance, misfolding of prion or tau proteins are associated with several neurodegenerative diseases. Here is the latest research on diseases caused by protein misfolding and aggregation.

Top 20 most recent papers
Nature Genetics

A slipped-CAG DNA-binding small molecule induces trinucleotide-repeat contractions in vivo

Nature GeneticsFebruary 16, 2020
Masayuki NakamoriChristopher E Pearson
Current Opinion in Immunology

Innate sensing of mechanical properties of brain tissue by microglia

Current Opinion in ImmunologyFebruary 15, 2020
Pinar Ayata, Anne Schaefer
1
Heart Rhythm : the Official Journal of the Heart Rhythm Society

Clinical and Functional Reappraisal of Alleged Type 5 Long QT Syndrome-Causative Genetic Variants in the KCNE1-Encoded minK β-Subunit

Heart Rhythm : the Official Journal of the Heart Rhythm SocietyFebruary 15, 2020
Ramin GarmanyMichael J Ackerman
5
Langmuir : the ACS Journal of Surfaces and Colloids

High-density DNA coatings on carboxylated colloids by DMTMM- and Azide-mediated coupling reactions

Langmuir : the ACS Journal of Surfaces and ColloidsFebruary 15, 2020
Joon Suk OhDavid J Pine
Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry

Stabilizing the Oil-in-Water Emulsions Using the Mixtures of Dendrobium Officinale Polysaccharides and Gum Arabic or Propylene Glycol Alginate

Molecules : a Journal of Synthetic Chemistry and Natural Product ChemistryFebruary 14, 2020
Bo WangDong Xiang
Soft Matter

PEGylated gene carriers in serum under shear flow

Soft MatterFebruary 14, 2020
Dongxiao YinDehai Liang
Human Mutation

Exome sequencing identifies the first genetic determinants of sirenomelia in human

Human MutationFebruary 15, 2020
François LecoquierreMarion Gerard
1
Analytical Biochemistry

A four-channel paper microfluidic device with gold nanoparticles and aptamers for seized drugs

Analytical BiochemistryFebruary 15, 2020
Ling Wang, Bruce McCord
Chemistry : a European Journal

Aggregation-induced Synergism via Hydrophobic-driven Self-assembly of Amphiphilic Oligonucleotides

Chemistry : a European JournalFebruary 16, 2020
Peng YangWenbin Liang
Chemical Science

Bifunctional ligand design for modulating mutant p53 aggregation in cancer

Chemical ScienceFebruary 15, 2020
Jessica J MillerTim Storr

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