Mitochondrial Malfunction & Autophagy

Autophagy is thus a key determinant for mitochondrial health and proper cell function. In addition to autophagy's significance in mitochondrial integrity, several lines of evidence suggest that mitochondria can also substantially influence the autophagic process.

October 19, 2021
Open Access

Nandrolone Decanoate supplementation promotes AMPK activation and divergent brain connectivity rearrangements in adult and aged mice.

BioRxiv : the Preprint Server for Biology
N. R. StrogulskiLuis V Portela
October 17, 2021

Alleviation of CCCP injury by Augmenter of liver regeneration via the PINK1/Parkin pathway-dependent mitophagy.

Experimental Cell Research
Jing ZhangWei An
October 16, 2021

RIPK3 signaling and its role in the pathogenesis of cancers.

Cellular and Molecular Life Sciences : CMLS
Shanhui LiuJiwang Zhang
October 16, 2021
Open Access

ULK1 promotes mitophagy via phosphorylation and stabilization of BNIP3.

Scientific Reports
Logan P PooleKay F Macleod
October 16, 2021

Melatonin mitigates Chloroquine-induced defects in porcine immature Sertoli cells.

Qiao MouCai-Xia Yang
October 16, 2021

Copper (Cu) induced changes of lipid metabolism through oxidative stress-mediated autophagy and Nrf2/PPARγ pathways.

The Journal of Nutritional Biochemistry
Chong-Chao ZhongZhi Luo
October 15, 2021
Open Access

Impaired placental mitophagy and oxidative stress are associated with dysregulated BNIP3 in preeclampsia.

Scientific Reports
Xiaobo ZhouPhilip Baker
October 15, 2021

Bisdemethoxycurcumin alleviates vandetanib-induced cutaneous toxicity in vivo and in vitro through autophagy activation.

Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie
Ying JinPeihua Luo
October 15, 2021
Open Access

Mitophagy in Diabetic Cardiomyopathy: Roles and Mechanisms.

Frontiers in Cell and Developmental Biology
Haoxiao ZhengYuli Huang
October 15, 2021

Phase separation of Nur77 mediates celastrol-induced mitophagy by promoting the liquidity of p62/SQSTM1 condensates.

Nature Communications
Shuang-Zhou PengXiao-Kun Zhang
October 14, 2021

Pharmacological basis and new insights of deguelin concerning its anticancer effects.

Pharmacological Research : the Official Journal of the Italian Pharmacological Society
Zhu Yue LinTang Ze Yao
October 13, 2021

Schizandrin A can inhibit non‑small cell lung cancer cell proliferation by inducing cell cycle arrest, apoptosis and autophagy.

International Journal of Molecular Medicine
Linhai ZhuJian Hu
October 13, 2021

Lactate and Pyruvate Activate Autophagy and Mitophagy that Protect Cells in Toxic Model of Parkinson's Disease.

Molecular Neurobiology
Evgeniya I FedotovaAlexey V Berezhnov
October 13, 2021
Open Access

EF24 exerts cytotoxicity against NSCLC via inducing ROS accumulation.

Cancer Cell International
Minghui ChangCuijuan Wang

Sign up to follow this feed and discover related papers.

Related Feeds

ATG proteins

The discovery of autophagy-related ('ATG') proteins in the 1990s greatly advanced the mechanistic understanding of autophagy and clarified the fact that autophagy serves important roles in various biological processes.

Aging & Diabetes

This feed focuses on the role of the aging process on developing diabetes.

Aging-Associated Metabolic Disorders

Age is associated with many metabolic disorders including cardiovascular diseases, type 2 diabetes, stroke and heart disease. The mediators in aging process have been suggested to play a part in the cellular processes responsible for these metabolic disorders. Here is the latest research on aging-associated metabolic disorders.

Apoptotic Caspases

Apoptotic caspases belong to the protease enzyme family and are known to play an essential role in inflammation and programmed cell death. Here is the latest research.


An autophagosome is the formation of double-membrane vesicles that involve numerous proteins and cytoplasmic components. These double-membrane vesicles are then terminated at the lysosome where they are degraded. Discover the latest research on autophagosomes here.

Autophagy & Aging: Inhibitors

The feed focuses on the role of nuclear export inhibitors and their effect on autophagy and the aging process.

Autophagy & Disease

Autophagy is an important cellular process for normal physiology and both elevated and decreased levels of autophagy are associated with disease. Here is the latest research.

Autophagy & Metabolism

Autophagy preserves the health of cells and tissues by replacing outdated and damaged cellular components with fresh ones. In starvation, it provides an internal source of nutrients for energy generation and, thus, survival. A powerful promoter of metabolic homeostasis at both the cellular and whole-animal level, autophagy prevents degenerative diseases. It does have a downside, however--cancer cells exploit it to survive in nutrient-poor tumors.

Autophagy & Model Organisms

Autophagy is a cellular process that allows degradation by the lysosome of cytoplasmic components such as proteins or organelles. Here is the latest research on autophagy & model organisms

Autophagy Networks

Autophagy is a lysosomal pathway that involves degradation of proteins and functions in normal growth and pathological conditions, through a series of complex networks. The catabolic process involves delivery of proteins and organelles to the lysosome. Here is the latest research on autophagy networks.

© 2021 Meta ULC. All rights reserved