Mitotic-exit networks with cytokinesis

Cytokinesis is the highly regulated process that physically separates daughter and mother cells in late mitosis. The mitotic-exit network (MEN), the signalling pathway that drives mitotic exit, directly regulates cytokinesis. Discover the latest research on mitotic-exit networks with cytokinesis here.

November 26, 2021

Chromatin bridges, not micronuclei, activate cGAS after drug-induced mitotic errors in human cells.

Proceedings of the National Academy of Sciences of the United States of America
Patrick J FlynnTimothy J Mitchison
November 25, 2021

High-Throughput Screening Platform in Postnatal Heart Cells and Chemical Probe Toolbox to Assess Cardiomyocyte Proliferation.

Journal of Medicinal Chemistry
Carmen Carrillo GarcíaDennis Schade
October 30, 2021

Chlamydia and HPV induce centrosome amplification in the host cell through additive mechanisms.

Cellular Microbiology
Kevin WangChristine Sütterlin
October 22, 2021

Localization of the ubiquitin ligase Dma1 to the fission yeast contractile ring is modulated by phosphorylation.

FEBS Letters
Jun-Song ChenKathleen L Gould
October 21, 2021
Open Access

Systematic identification of yeast mutants with increased rates of cell death reveals rapid stochastic necrosis associated with cell division

BioRxiv : the Preprint Server for Biology
Alexander Ivanovich AlexandrovV. N. Gladyshev
October 20, 2021

Changing places: Chromosomal Passenger Complex relocation in early anaphase.

Trends in Cell Biology
Michael A Hadders, Susanne M A Lens
October 19, 2021

The regulation of actin dynamics during cell division and malignancy.

American Journal of Cancer Research
Paulius Gibieža, Vilma Petrikaitė
October 14, 2021

Quantitative differences between cyclin-dependent kinases underlie the unique functions of CDK1 in human cells.

Cell Reports
Ho Wai LauRandy Yat Choi Poon
September 30, 2021
Open Access

Pathogenic mutations in the chromokinesin KIF22 disrupt anaphase chromosome segregation

BioRxiv : the Preprint Server for Biology
A. F. ThompsonJason Stumpff
September 29, 2021
Open Access

Trypanosome morphogenesis involves recruitment of a pleckstrin homology domain protein by an orphan kinesin to the microtubule quartet

BioRxiv : the Preprint Server for Biology
C. BenzHassan Hashimi
September 29, 2021
Open Access

Prognostic Impact and Functional Annotations of KIF11 and KIF14 Expression in Patients with Colorectal Cancer.

International Journal of Molecular Sciences
Izabela Neska-DługoszAnna Klimaszewska-Wiśniewska
September 27, 2021
Open Access

SIN-like pathway kinases regulate the end of mitosis in the methylotrophic yeast Ogataea polymorpha

BioRxiv : the Preprint Server for Biology
S. JiangyanHiromi Maekawa
September 17, 2021

Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer.

Nature Communications
Jing LiThomas G P Grünewald
September 15, 2021

Downregulation of the Tem1 GTPase by Amn1 after cytokinesis involves both nuclear import and SCF-mediated degradation.

Journal of Cell Science
Alain Devault, Simonetta Piatti
September 12, 2021
Open Access

MKLP2 functions in early mitosis to ensure proper chromosome congression

BioRxiv : the Preprint Server for Biology
M. S. SchrockMatthew K. Summers

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