MLL-r Leukemia

Mixed lineage leukemia-1 (MLL-1) is a particular type of acute leukemia from the mutation of the MLL/KMT2A gene. This mutation can be seen in pediatrics, adults and therapy-induced acute leukemia’s. Discover the latest research on MLL-r leukemia here.

July 2, 2020
Open Access

Poor Prognosis Biomolecular Factors Are Highly Frequent in Childhood Acute Leukemias From Oaxaca, Mexico

Technology in Cancer Research & Treatment
Gerardo Juárez-AvendañoJuan Carlos Balandrán
June 27, 2020
Open Access

Nonclinical Safety Assessment of AMG 553, an Investigational Chimeric Antigen Receptor (CAR) T-cell Therapy for the Treatment of Acute Myeloid Leukemia

Toxicological Sciences : an Official Journal of the Society of Toxicology
Christine KarbowskiHerve Lebrec
July 2, 2020
Review
Open Access

Immunotherapy in Myeloproliferative Diseases

Cells
Lukas M Braun, Robert Zeiser
July 3, 2020
Comment / Editorial
Open Access

NUP98 and KMT2A : usually the bride rather than the bridesmaid

Haematologica
Alexandre Fagnan, Thomas Mercher
July 2, 2020
Open Access

Identifying novel genetic alterations in pediatric acute lymphoblastic leukemia based on copy number analysis

Molecular Cytogenetics
Jéssica Almeida Batista-GomesAndré Salim Khayat
July 1, 2020

Pharmacological disruption of the Notch transcription factor complex

Proceedings of the National Academy of Sciences of the United States of America
Rajwinder LehalFreddy Radtke
June 27, 2020
Review

Chimeric Antigen Receptors for the Tumour Microenvironment

Advances in Experimental Medicine and Biology
Rosemary HabibKavitha Gowrishankar
July 7, 2020

Familial leukemia due to germline RUNX1 mutations: lessons learned from two decades of research and unsolved problems

[Rinshō ketsueki] The Japanese journal of clinical hematology
Motomi Osato, Akiko Nambu
June 28, 2020
Open Access

Repurposing anthelmintic agents to eradicate resistant leukemia

Blood Cancer Journal
Caterina MezzatestaBeat C Bornhauser
July 6, 2020
Open Access

Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion

Nature Communications
Yi ZhangTatiana G Kutateladze
July 1, 2020

Oxidative stress abrogates the degradation of KMT2D to promote degeneration in nucleus pulposus

Biochimica Et Biophysica Acta. Molecular Basis of Disease
Wenbin XuXiangqian Fang

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