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Molecular diagnostic strategies in prion disease

Molecular diagnostic strategies in prion disease diagram by Jensflorian
Jensflorian

Prion diseases are fatal neurodegenerative and infectious disorders characterized by structural transition of the host-encoded cellular prion protein into the aberrantly folded pathologic isoform of the protein. Here is the latest research on molecular diagnostic strategies for prion diseases.

Top 20 most recent papers
Nature Communications

Early preclinical detection of prions in the skin of prion-infected animals

Nature CommunicationsJanuary 16, 2019
Zerui WangWen-Quan Zou
16
8
16
Molecular Neurodegeneration

Dural lymphatics regulate clearance of extracellular tau from the CNS

Molecular NeurodegenerationFebruary 27, 2019
Tirth K PatelDavid. M. Holtzman
31
1
2
61
Annals of Neurology

Sporadic Fatal Insomnia in Europe: Phenotypic Features and Diagnostic Challenges

Annals of NeurologyJuly 27, 2018
Samir Abu-RumeilehPiero Parchi
5
1
22
The American Journal of Sports Medicine

Chondrogenic Progenitor Cells Exhibit Superiority Over Mesenchymal Stem Cells and Chondrocytes in Platelet-Rich Plasma Scaffold-Based Cartilage Regeneration

The American Journal of Sports MedicineJune 13, 2019
Ke-Tao WangHeng Zhu
Bulletin de l'Académie nationale de médecine

History of Prions and transmission of protein misfolding

Bulletin de l'Académie nationale de médecineJune 1, 2015
Jean-Jacques HauwJean-Philippe Brandel
Methods in Molecular Biology

Study of Amyloids Using Yeast

Methods in Molecular BiologyJanuary 1, 2018
Reed Brendon WicknerHerman K Edskes
International Psychogeriatrics

The most problematic symptoms of prion disease - an analysis of carer experiences

International PsychogeriatricsOctober 26, 2018
Liz FordSimon H Mead
5
11
PloS One

Enhanced detection of prion infectivity from blood by preanalytical enrichment with peptoid-conjugated beads

PloS OneSeptember 12, 2019
Simone HornemannAdriano Aguzzi
7
5
MBio

Prion Seeds Distribute throughout the Eyes of Sporadic Creutzfeldt-Jakob Disease Patients

MBioNovember 20, 2018
Christina Doriana OrrùChristina J Sigurdson
72
22
1
17
1
The Lancet. Haematology

Assessment of ASC specks as a putative biomarker of pyroptosis in myelodysplastic syndromes: an observational cohort study

The Lancet. HaematologyAugust 4, 2018
Ashley A BasiorkaAlan F List
3
1
19
Handbook of Clinical Neurology

Iatrogenic Creutzfeldt-Jakob disease

Handbook of Clinical NeurologyJanuary 1, 2018
Atsushi KobayashiHidehiro Mizusawa
Journal of Neuropathology and Experimental Neurology

Novel Spiroplasma sp. Isolated From CWD Is an Extreme Bacterial Thermoacidophile That Survives Autoclaving, Boiling, Formalin Treatment, and Significant Gamma Irradiation

Journal of Neuropathology and Experimental NeurologySeptember 13, 2019
Frank O BastianWei-Hsung Wang
5
2
NeuroImage. Clinical

Prion disease diagnosis using subject-specific imaging biomarkers within a multi-kernel Gaussian process

NeuroImage. ClinicalOctober 25, 2019
Liane S CanasMarc Modat
4
Methods in Cell Biology

Correlating light microscopy with serial block face scanning electron microscopy to study mitotic spindle architecture

Methods in Cell BiologyJanuary 1, 2018
Nicholas I Clarke, Stephen J Royle
4
6
Methods in Molecular Biology

Bioluminescence Imaging of Neuroinflammation in a Mouse Model of Parkinson's Disease

Methods in Molecular BiologyNovember 14, 2019
Maria Eugenia Bernis, Gültekin Tamgüney
1
Proceedings of the National Academy of Sciences of the United States of America

Million-fold sensitivity enhancement in proteopathic seed amplification assays for biospecimens by Hofmeister ion comparisons

Proceedings of the National Academy of Sciences of the United States of AmericaOctober 24, 2019
Michael A MetrickByron W Caughey
16
1
Langmuir : the ACS Journal of Surfaces and Colloids

Graphene Oxide Quantum Dot Alters Amyloidogenicity of Hen Egg White Lysozyme via Modulation of Protein Surface Character

Langmuir : the ACS Journal of Surfaces and ColloidsNovember 24, 2018
Deependra Kumar BanSubhankar Paul
1
6
Canada Communicable Disease Report = Relevé Des Maladies Transmissibles Au Canada

A new diagnostic test for Creutzfeldt-Jakob disease: Real-time quaking-induced conversion (RT-QulC)

Canada Communicable Disease Report = Relevé Des Maladies Transmissibles Au CanadaAugust 6, 2015
Debra GodalJ David Knox
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova

Human prion diseases: current issues

Zhurnal nevrologii i psikhiatrii imeni S.S. KorsakovaJanuary 1, 2018
Nikolay N ZavadenkoE N Saverskaya
1
The Neurohospitalist

National Variability in Prion Disease-Related Safety Policies for Neurologic Procedures

The NeurohospitalistSeptember 20, 2019
Katherine WerbanethCarl A Gold

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