Motor Neuron Disease

Motor neuron diseases such as amyotrophic lateral sclerosis and spinal muscular atrophy are progressive neurodegenerative diseases that result in the death of motor neurons. Discover the latest research on motor neuron disease here.

January 21, 2022
Open Access

MRI Volumetric Analysis of the Thalamus and Hypothalamus in Amyotrophic Lateral Sclerosis.

Frontiers in Aging Neuroscience
Shan YeDongsheng Fan
January 21, 2022
Case Report

Total knee replacement in a polio patient with prior extension osteotomy: a case report.

Journal of Surgical Case Reports
Khalid A AlsheikhAli A Alhandi
January 21, 2022

Revealing the Mutational Spectrum in Southern Africans With Amyotrophic Lateral Sclerosis.

Neurology. Genetics
Melissa NelJeannine M Heckmann
January 21, 2022

Body mass index in type 2 spinal muscular atrophy: a longitudinal study.

European Journal of Pediatrics
Gloria FerrantiniItalian ISMAC study group
January 21, 2022
Review

Altered Blood-Brain Barrier and Blood-Spinal Cord Barrier Dynamics in Amyotrophic Lateral Sclerosis: Impact on Medication Efficacy and Safety.

British Journal of Pharmacology
Yijun Pan, Joseph A Nicolazzo
January 21, 2022

High incidence of amyotrophic lateral sclerosis in the Faroe Islands 2010-2020.

Annals of Clinical and Translational Neurology
Malan JohansenMaria Skaalum Petersen
January 21, 2022

Passive immunization against phosphorylated tau improves features of Huntington's disease pathology.

Molecular Therapy : the Journal of the American Society of Gene Therapy
Melanie AlpaughFrancesca Cicchetti
January 21, 2022
Review

Carving the senescent phenotype by the chemical reactivity of catecholamines: An integrative review.

Ageing Research Reviews
Aleksei G Golubev
January 20, 2022
Preprint
Open Access

Selective inhibition of goal-directed actions in the mesencephalic locomotor region

BioRxiv : the Preprint Server for Biology
N. K. GutJuan Mena-Segovia
January 20, 2022
Open Access

Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1.

Genome Medicine
Restuadi RestuadiFleur C Garton
January 20, 2022

Integrated genome and transcriptome analyses reveal the mechanism of genome instability in ataxia with oculomotor apraxia 2.

Proceedings of the National Academy of Sciences of the United States of America
Radhakrishnan KanagarajStephen C West
January 20, 2022
Review

Regulation of Neurodegeneration-associated Protein Fragments by the N-degron Pathways.

Neurotoxicity Research
Mohamed A EldeebRichard P Fahlman
January 20, 2022

The Gpx4NIKO Mouse Is a Versatile Model for Testing Interventions Targeting Ferroptotic Cell Death of Spinal Motor Neurons.

Neurotoxicity Research
Robert Cole EvansQitao Ran
January 20, 2022

Targeted gene silencing in the nervous system with CRISPR-Cas13.

Science Advances
Jackson E PowellThomas Gaj
January 20, 2022

Mutation in senataxin alters the mechanism of R-loop resolution in amyotrophic lateral sclerosis 4.

Brain : a Journal of Neurology
Annapoorna KannanLaxman Gangwani
January 20, 2022

Genome-wide identification of the genetic basis of amyotrophic lateral sclerosis.

Neuron
Sai ZhangMichael P Snyder

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