Mouse Models In Cancer

Genetically engineered mouse models provide researchers with a better understanding of cancer genes and tumor biomarkers, the mechanisms underlying tumor initiation and metastasis, and novel therapeutic strategies in cancer. Discover the latest research on mouse models in cancer here.

September 25, 2020
Open Access

Paradoxical Role of AT-rich Interactive Domain 1A in Restraining Pancreatic Carcinogenesis

Cancers
Sammy Ferri-BorgognoSonal Gupta
July 25, 2020

Emergence of a High-Plasticity Cell State during Lung Cancer Evolution

Cancer Cell
Nemanja Despot MarjanovicTuomas Tammela
June 25, 2020
Open Access

Metabolic Landscape of a Genetically Engineered Mouse Model of IDH1 Mutant Glioma

Cancers
Victor Ruiz-RodadoMioara Larion
July 29, 2020
Review
Open Access

Engineering and combining oncolytic measles virus for cancer therapy

Cytokine & Growth Factor Reviews
Mathias F LeberGuy Ungerechts
June 24, 2020
Open Access

Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth

ELife
Caroline ContatEtienne Meylan
August 20, 2020
Preprint
Open Access

Niche-derived soluble DLK1 promotes glioma stemness and growth

BioRxiv : the Preprint Server for Biology
E. S. GrassiAlexander Pietras
August 28, 2020

A Genetically Engineered Mouse Model of Malignant Testicular Germ Cell Tumors

Methods in Molecular Biology
Amy M LyndakerRobert S Weiss
July 16, 2020

RAD51AP1 deficiency reduces tumor growth by targeting stem cell self-renewal

Cancer Research
Allison E BridgesMuthusamy Thangaraju
August 25, 2020

Perfusion and Inflation of the Mouse Lung for Tumor Histology

Journal of Visualized Experiments : JoVE
Mackenzie L DavenportMick D Edmonds
September 12, 2020

SPR064, a pro-drug of paclitaxel, has anti-tumorigenic effects in endometrial cancer cell lines and mouse models

American Journal of Translational Research
Xiaoling ZhaoVictoria L Bae-Jump
July 15, 2020

Glucose-6-Phosphate Dehydrogenase Is Not Essential for K-Ras-Driven Tumor Growth or Metastasis

Cancer Research
Jonathan M GhergurovichJoshua D Rabinowitz
September 11, 2020

An engineered pancreatic cancer model with intra-tumoral heterogeneity of driver mutations

Lab on a Chip
Hye-Ran MoonBumsoo Han
September 3, 2020
Open Access

Oncolytic virus therapy benefits from control theory

Royal Society Open Science
Anet J N AnelonePablo S Rivadeneira
September 17, 2020

TSPO-targeted PET and Optical Probes for the Detection and Localization of Pre-Malignant and Malignant Pancreatic Lesions

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
Allison S CohenH Charles Manning
September 15, 2020
Open Access

Light-Independent Biological Conversion of CO2

Joule
Sevcan Erşan, Junyoung O Park
August 28, 2020

Pten and Dicer1 loss in the mouse uterus causes poorly differentiated endometrial adenocarcinoma

Oncogene
Xiyin WangShannon M Hawkins
September 5, 2020
Review
Open Access

Study on the hepatocellular carcinoma model with metastasis

Genes & Diseases
Yu-Lin Lin, Yan Li
July 9, 2020
Review
Open Access

Studies of nanoparticle delivery with in vitro bio-engineered microtissues

Bioactive Materials
Mingze SunKazunori Hoshino

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