Multi-drug Resistance

Multi-drug resistance or multiresistance is antimicrobial resistance shown by a species of microorganism to multiple antimicrobial drugs. Discover the latest research on multi-drug resistance here.

January 19, 2022

2‑Cl‑IB‑MECA regulates the proliferative and drug resistance pathways, and facilitates chemosensitivity in pancreatic and liver cancer cell lines.

International Journal of Molecular Medicine
Jana KotulovaPetr Dzubak
January 19, 2022

Antimicrobial Peptides from Human Microbiome Against Multidrug Efflux Pump of Pseudomonas aeruginosa: a Computational Study.

Probiotics and Antimicrobial Proteins
Viswajit Mulpuru, Nidhi Mishra
January 19, 2022

Targeted disruption of mitochondria potently reverses multidrug resistance in cancer therapy.

British Journal of Pharmacology
Dingkang LiuXiangdong Gao
January 19, 2022

Haemin deprivation renders Bacteroides fragilis hypersusceptible to metronidazole and cancels high-level metronidazole resistance.

The Journal of Antimicrobial Chemotherapy
Ana PaunkovDavid Leitsch
January 19, 2022

Antimicrobial activities of aztreonam-avibactam and comparator agents tested against Enterobacterales from European hospitals analysed by geographic region and infection type (2019-2020).

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
Helio S SaderMariana Castanheira
January 18, 2022
Open Access

Activation of the Integrated Stress Response overcomes multidrug resistance in FBXW7-deficient cells

BioRxiv : the Preprint Server for Biology
L. Sanchez-BurgosOscar Fernandez-Capetillo
January 18, 2022
Open Access

Dual Targeting of FLT3 and LSD1 Disrupts the MYC Super-Enhancer Complex in Acute Myeloid Leukemia

BioRxiv : the Preprint Server for Biology
W. M. YasharTheodore P Braun
January 17, 2022
Open Access

[Treatment of drug-resistant tuberculosis in adults and children. A narrative review].

Domingo J PalmeroPablo J González Montaner
January 17, 2022
Open Access

A human-based multi-gene signature enables quantitative drug repurposing for metabolic disease.

James A TimmonsStuart M Phillips
January 17, 2022

Inducible boron resistance via active efflux in Lysinibacillus and Enterococcus isolates from boron-contaminated agricultural soil.

Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine
Subhajit SenRanadhir Chakraborty
January 17, 2022
Open Access

A critical review on modulators of Multidrug Resistance Protein 1 in cancer cells.

Vivian Osei Poku, Surtaj Hussain Iram
January 17, 2022
Open Access

Heteroresistance to Amikacin in Carbapenem-Resistant Klebsiella pneumoniae Strains.

Frontiers in Microbiology
Feiyang ZhangYingshun Zhou
January 17, 2022

Pore formation by pore forming membrane proteins towards infections.

Advances in Protein Chemistry and Structural Biology
Achinta Sannigrahi, Krishnananda Chattopadhyay
January 17, 2022

Telacebec: an investigational antibiotic for the treatment of tuberculosis (TB).

Expert Opinion on Investigational Drugs
Bei Shi Lee, Kevin Pethe

Sign up to follow this feed and discover related papers.

Related Feeds

ABC Transporters & Multidrug Resistance

ABC Transporters or ATP-Binding Cassette Transporters are responsible for pumping out antibiotics in the cell and can lead to multidrug resistance in bacteria. Discover the latest research on ABC Transporters & Multidrug Resistance here.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

CRISPR Screens in Drug Resistance

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of CRISPR-Cas system in high-throughput genome-wide screens to identify genes that may confer drug resistance.

Drug-Inactivating Enzymes & Resistance

Drug inactivation or modification is one of the mechanisms through which resistance occurs. For instance, some penicillin-resistant bacteria produce beta-lactamases to enzymatically deactivate Penicillin G. Here is the latest research on drug inactivating enzymes and resistance.

Drug-Resistant Infections

Drug resistant infections are one of the biggest threats in our public health care system. Discover the latest research here.

Efflux-Mediated Drug Resistance

Efflux-mediated drug resistance is one mechanism where bacteria can express proteins that pump out antibiotics, thereby rendering therapy ineffective. Discover the latest research on efflux-mediated drug resistance here.

Horizontal Gene Transfer

Horizontal gene transfer is a mechanism in which genetic material is transmitted from one organism to another organism. This process is used by bacteria to acquire antibiotic resistance genes and is important for bacterial evolution. Discover the latest research on horizontal gene transfer here.

Infectious Disease - Sequencing

Infectious Disease Sequencing is a emerging field due to low-cost massively parallel sequencing and allows researchers to monitor outbreaks of infectious pathogens. Discover the latest research on Infectious Disease Sequencing here.

MRSA Infections

MRSA Infections or Methicillin-resistant Staphylococcus aureus infections are difficult to treat due to resistance to the beta-lactam family of antibiotics. MRSA infections are commonly acquired in hospitals. Discover the latest research on MRSA Infections here.

Metabolic Pathways & Drug Resistance

Metabolic pathways have been used as drug targets in the development of therapeutic compounds. Change of metabolic pathways can render the loss of therapeutic effects, a mechanism that is commonly found in drug resistance. Discover the latest research on metabolic pathways and drug resistance here.

© 2022 Meta ULC. All rights reserved