Myeloid Stem Cells & CML

Chronic Myeloid Leukemia (CML) is a stem cell cancer that arises due to the fusion and constitutive expression of BCR-ABL1 in hematopoietic stem cells, which give rise to both myeloid and lymphoid cell lineages. CML is characterized by increased and unregulated proliferation of myeloid cells. Here is the latest research.

September 20, 2021
Preprint
Open Access

Progenitor-intrinsic Metabolic Sensing Promotes Hematopoietic Homeostasis

BioRxiv : the Preprint Server for Biology
H. A. PizzatoDeepta Bhattacharya
September 20, 2021

Changes in Bone Marrow Stromal Progenitor Cells in Patients with Hematoblastosis at the Onset of the Disease.

Bulletin of Experimental Biology and Medicine
N A PetinatiV G Savchenko
September 20, 2021

Lead Optimization and Structure-Activity Relationship Studies on Myeloid Ecotropic Viral Integration Site 1 Inhibitor.

Journal of Medicinal Chemistry
Bengisu TurgutalpMine Yarim
September 20, 2021

Response to Tyrosine Kinase Inhibitors in Real-World Patients With Chronic Myeloid Leukemia.

The Annals of Pharmacotherapy
Andy H SzetoDaniel J Crona
September 20, 2021
Review

A systematic literature review of disease burden and clinical efficacy for patients with relapsed or refractory acute myeloid leukemia.

American Journal of Blood Research
Esther Natalie OlivaAntonio M Almeida
September 20, 2021

miR-506 in patients with chronic myeloid leukemia and its effect on apoptosis of K562 cells.

American Journal of Translational Research
Nafei ChenLiyun Zhao
September 20, 2021

miR-497-5p induces apoptosis in K562 cells by downregulating ROCK1.

American Journal of Translational Research
Nafei ChenLiyun Zhao
September 20, 2021
Review

Current Progress in Delineating the Roles of Pseudokinase TRIB1 in Controlling Human Diseases.

Journal of Cancer
Xuelian ZhangXiaobo Sun
September 20, 2021
Open Access

Dysregulation of Principal Circulating miRNAs in Non-human Primates Following Ischemic Stroke.

Frontiers in Neuroscience
Jian ChenXunming Ji
September 17, 2021

Myeloid Malignancies: Recognizing the Risk of Germline Predisposition and Supporting Patients and Families.

Clinical Journal of Oncology Nursing
Patricia Friend, Suzanne M Mahon
September 16, 2021

Blastic plasmacytoid dendritic-cell neoplasia: a challenging case report.

Journal of Cancer Research and Clinical Oncology
Ruth-Miriam KoerberAnnkristin Heine
September 16, 2021
Case Report

Concurrent Diagnosis of Acute Myeloid Leukemia and Symptomatic COVID-19 Infection: a Case Report Successfully Treated with Azacitidine-Venetoclax Combination.

Mediterranean Journal of Hematology and Infectious Diseases
Daniela TaurinoFederico Lussana
September 16, 2021

Targeting Wnt signaling in acute myeloid leukemia stem cells.

Haematologica
Felice PepeRamiro Garzon
September 16, 2021

In-depth time-dependent analysis of the benefit of Allo-HSCT for elderly patients with CR1 AML: a FILO study.

Blood Advances
Raynier DevillierAnne Huynh
September 16, 2021

IL-1 Mediates Microbiome-Induced Inflamm-Ageing of Hematopoietic Stem Cells in Mice.

Blood
Larisa Vladimirovna KovtonyukMarkus G Manz

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