Neural Control of FGF21 & SIRT1

Fibroblast growth factor 21 (FGF21) is a liver‐derived hormone that selectively inhibits consumption of sugars and the primary product of their fermentation, ethanol, but not intake of fat, protein or complex carbohydrates. SIRT1 is a protein of the sirtuin family linked with deacetylation of proteins and contributes to reaction to stressor and longevity. Here is the latest research on neural control of FGF21 and SIRT1.

December 5, 2021

Integrated omics analysis reveals sirtuin signaling is central to hepatic response to a high fructose diet.

BMC Genomics
Laura A CoxMichael Olivier
December 4, 2021

Hippocampal SIRT1 improves cognitive impairment by deacetylating tau protein in diabetic models.

European Journal of Pharmacology
Naihao ShiChenghua Zhou
December 4, 2021
Open Access

Mitochondrial Sirtuin TcSir2rp3 Affects TcSODA Activity and Oxidative Stress Response in Trypanosoma cruzi.

Frontiers in Cellular and Infection Microbiology
Leila Dos Santos MouraNilmar Silvio Moretti
December 3, 2021
Open Access

Senolytic effects of quercetin in an in vitro model of pre-adipocytes and adipocytes induced senescence.

Scientific Reports
Elena ZoicoMauro Zamboni
December 3, 2021
Review

SIRT1-FOXOs Activity Regulates Diabetic Complications.

Pharmacological Research : the Official Journal of the Italian Pharmacological Society
Manjiri P JalgaonkarManisha J Oza
December 3, 2021
Review

Mitochondrial sirtuins, metabolism, and aging.

Journal of Genetics and Genomics = Yi Chuan Xue Bao
Zhejun JiJing Qu
December 2, 2021

Effects and mechanisms of CTRP3 overexpression in secondary brain injury following intracerebral hemorrhage in rats.

Experimental and Therapeutic Medicine
Yu WanShaohua Wang
November 29, 2021
Open Access

Proteome Analysis of the Hypothalamic Arcuate Nucleus in Chronic High-Fat Diet-Induced Obesity.

BioMed Research International
Chang Yeon KimHyung Jin Choi
November 29, 2021

Endothelial SIRT1 as a target for the prevention of arterial ageing: promises and challenges.

Journal of Cardiovascular Pharmacology
Musammat Kulsuma BegumYu Wang
November 29, 2021

β-Carotene stimulates browning of 3T3-L1 white adipocytes by enhancing thermogenesis via the β3-AR/p38 MAPK/SIRT signaling pathway.

Phytomedicine : International Journal of Phytotherapy and Phytopharmacology
Sulagna Mukherjee, Jong Won Yun
November 29, 2021

A novel role of CRTC2 in promoting nonalcoholic fatty liver disease.

Molecular Metabolism
Hye-Sook HanSeung-Hoi Koo
November 29, 2021

Biochemical genesis of enzymatic and non-enzymatic post-translational modifications.

Molecular Aspects of Medicine
Erin Q JenningsJames J Galligan

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