Neurodegeneration And Aging

This feed focuses on genetic aspects of neurodegeneration and aging, with emphasis on the role of protein aggregates in neurodegenerative diseases including Alzhiemer’s. Here is the latest research.

September 16, 2021

Glucocerebrosidase dysfunction in neurodegenerative disease.

Essays in Biochemistry
Sarah M Brooker, Dimitri Krainc
September 16, 2021

A geometric morphometric assessment of shape variation in adult pelvic morphology.

American Journal of Physical Anthropology
Samantha L Cox
September 16, 2021

The interrelationship between female reproductive aging and survival.

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Jeffrey B MasonKate C Parkinson
September 16, 2021
Open Access

Cortical structure and the risk for Alzheimer's disease: a bidirectional Mendelian randomization study.

Translational Psychiatry
Bang-Sheng WuJin-Tai Yu
September 16, 2021
Open Access

Adult-onset CNS myelin sulfatide deficiency is sufficient to cause Alzheimer's disease-like neuroinflammation and cognitive impairment.

Molecular Neurodegeneration
Shulan QiuXianlin Han
September 16, 2021
Open Access

Integrating Transcriptomics, Genomics, and Imaging in Alzheimer's Disease: A Federated Model

BioRxiv : the Preprint Server for Biology
J. WuYalin Wang
September 16, 2021

Adiponectin, leptin and resistin and the risk of dementia.

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Sanne S MooldijkM Arfan Ikram
September 16, 2021
Comment / Editorial

Do peripheral protein oligomers in neurodegenerative diseases shape T cell responses beyond the brain?

Annabelle Ferguson, Simon Milling
September 16, 2021

Epigenetic clock and DNA methylation analysis of porcine models of aging and obesity.

Kyle M SchachtschneiderSteve Horvath
September 16, 2021

Mitochondrial pathway polygenic risk scores are associated with Alzheimer's Disease.

Neurobiology of Aging
Devashi PaliwalAlzheimer's Disease Neuroimaging Initiative
September 16, 2021

Changes in histaminergic system in neuropsychiatric disorders and the potential treatment consequences.

Current Neuropharmacology
Ling Shan, Dick F Swaab
September 15, 2021
Open Access

Integration of multidimensional splicing data and GWAS summary statistics for risk gene discovery

BioRxiv : the Preprint Server for Biology
Y. JiBingshan Li
September 15, 2021
Open Access

Synthesis of human amyloid restricted to liver results in an Alzheimer disease-like neurodegenerative phenotype.

PLoS Biology
Virginie LamJohn C L Mamo
September 15, 2021

Two Types of Mouse Models for Sarcopenia Research: Senescence Acceleration and Genetic Modification Models.

Journal of Bone Metabolism
Kyung-Wan BaekJun-Il Yoo

Sign up to follow this feed and discover related papers.

Related Feeds

ATG proteins

The discovery of autophagy-related ('ATG') proteins in the 1990s greatly advanced the mechanistic understanding of autophagy and clarified the fact that autophagy serves important roles in various biological processes.

Age-related Dementia

Dementias are a group of conditions, including Alzheimer's disease, vascular dementia, and frontotemporal dementia, characterized by deficiencies in cognitive abilities. Age-related dementia refers to dementias that occur in older individuals, usually 60+ years old, in contrast to early-onset dementia. Follow the latest research on age-related dementia here.

Aging & Diabetes

This feed focuses on the role of the aging process on developing diabetes.

Aging-Associated Metabolic Disorders

Age is associated with many metabolic disorders including cardiovascular diseases, type 2 diabetes, stroke and heart disease. The mediators in aging process have been suggested to play a part in the cellular processes responsible for these metabolic disorders. Here is the latest research on aging-associated metabolic disorders.

Alzheimer's Disease: APOE

Apolipoprotein E (APOE) polymorphic alleles are major genetic risk factors for Alzheimer's disease. Discover the latest research on APOE and other genetic determinants of Alzheimer's disease here.

Alzheimer's Disease: APP

Amyloid precursor protein (APP) proteolysis is critical for the development of Alzheimer's disease, a neurodegenerative disease associated with accumulation of amyloid plaques in the brain. Here is the latest research on APP and Alzheimer's disease.

Alzheimer's Disease: Amyloid Beta

Alzheimer's disease is a neurodegenerative disease associated with the accumulation of amyloid plaques in the brain; these plaques are comprised of amyloid beta deposits. Here is the latest research in this field.

Alzheimer's Disease: Animal Models

Alzheimer's disease is a neurodegenerative disease which can be studied using various experimental systems. This feed focuses on animal models used for Alzheimer's disease research.

Alzheimer's Disease: Early Markers

Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive cognitive and behavioral decline. Targeting markers in the earliest stages of the disease may mitigate the progression of AD. This feed focuses on early diagnosis and markers, as well as environmental, pharmacological, and drug-response biomarkers associated with this disease.

Alzheimer's Disease: Endosomes

Dysfunctional endosomal trafficking may be associated with Alzheimer’s disease (AD) pathology. Targeting the endosome may advance treatment options for AD. Here is the latest research on endosomes and AD.

© 2021 Meta ULC. All rights reserved