Neurodegeneration: Autophagy

Given that progression of neurodegenerative diseases can be driven by aggregation of misfolded proteins, autophagic activity is through to modulate the severity of neurodegenerative diseases. Here is the latest research on the influence of autophagy on neurodegeneration.

January 21, 2022
Review
Open Access

Autophagy of the Nucleus in Health and Disease.

Frontiers in Cell and Developmental Biology
Georgios Konstantinidis, Nektarios Tavernarakis
January 20, 2022

Liraglutide Regulates Mitochondrial Quality Control System Through PGC-1α in a Mouse Model of Parkinson's Disease.

Neurotoxicity Research
Pengyue WuYanqin Wang
January 19, 2022
Open Access

Idebenone improves motor dysfunction, learning and memory by regulating mitophagy in MPTP-treated mice.

Cell Death Discovery
Junqiang YanJiannan Wu
January 19, 2022

A cerebrospinal fluid microRNA analysis: Progressive supranuclear palsy.

Molecular Medicine Reports
Wakako NonakaTsutomu Masaki
January 19, 2022

mTOR Inhibition with Sirolimus in Multiple System Atrophy: A Randomized, Double-Blind, Placebo-Controlled Futility Trial and 1-Year Biomarker Longitudinal Analysis.

Movement Disorders : Official Journal of the Movement Disorder Society
Jose-Alberto PalmaHoracio Kaufmann
January 17, 2022
Review

The Role of ERK1/2 Pathway in the Pathophysiology of Alzheimer's Disease: An Overview and Update on New Developments.

Cellular and Molecular Neurobiology
Mohammad Rafi KhezriMorteza Ghasemnejad-Berenji
January 17, 2022
Review
Open Access

Effects of Polyphenols on Oxidative Stress, Inflammation, and Interconnected Pathways during Spinal Cord Injury.

Oxidative Medicine and Cellular Longevity
Sajad FakhriJianbo Xiao
January 15, 2022

Chronic lithium administration in a mouse model for Krabbe disease.

JIMD Reports
Ambra Del GrossoMarco Cecchini
January 15, 2022

The complex interplay between autophagy and cell death pathways.

The Biochemical Journal
Christina PloumiNektarios Tavernarakis
January 15, 2022

Neuroprotective effect of YIAEDAER peptide against Parkinson's disease like pathology in zebrafish.

Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie
Qingyu RenMeng Jin
January 14, 2022

Inhibiting mitochondrial fission rescues degeneration in hereditary spastic paraplegia neurons.

Brain : a Journal of Neurology
Zhenyu ChenXue-Jun Li
January 14, 2022

Broad activation of the Parkin pathway induces synaptic mitochondrial deficits in early tauopathy.

Brain : a Journal of Neurology
Yu Young JeongQian Cai
January 12, 2022
Open Access

Neurodegeneration and Astrogliosis in the Human CA1 Hippocampal Subfield Are Related to hsp90ab1 and bag3 in Alzheimer's Disease.

International Journal of Molecular Sciences
Melania Gonzalez-RodriguezDaniel Saiz-Sanchez
January 12, 2022
Review
Open Access

Metformin Repurposing for Parkinson Disease Therapy: Opportunities and Challenges.

International Journal of Molecular Sciences
Francesco AgostiniMarco Bisaglia
January 12, 2022
Review
Open Access

Covering the Role of PGC-1α in the Nervous System.

Cells
Zuzanna KuczynskaLeonora Buzanska
January 12, 2022

Screening the Efficacy of Melatonin on Neurodegeneration Mediated by Endoplasmic Reticulum Stress, Inflammation, and Oxidative Damage.

Applied Biochemistry and Biotechnology
Fathima Hajee Basha, S Hemalatha

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