Neurodegeneration: Endolysosomes

This feed focuses on the role of the endolysosome, an organelle involved in protein degradation. Defects in the endolysosome may cause neurodegenerative diseases, such as Alzheimer’s Disease.

September 20, 2021

Microsecond dynamics during the binding-induced folding of an intrinsically disordered protein.

Journal of Molecular Biology
Sreemantee SenJayant B Udgaonkar
September 20, 2021
Open Access

KinOrtho: a method for mapping human kinase orthologs across the tree of life and illuminating understudied kinases.

BMC Bioinformatics
Liang-Chin HuangNatarajan Kannan
September 18, 2021
Preprint
Open Access

A CLN6-CRMP2-KLC4 complex regulates anterograde ER-derived vesicle trafficking in cortical neurites

BioRxiv : the Preprint Server for Biology
S. Y. KohJill M Weimer
September 17, 2021
Open Access

Modulation of Glial Function in Health, Aging, and Neurodegenerative Disease.

Frontiers in Cellular Neuroscience
Kendra L HanslikTyler K Ulland
September 17, 2021
Review
Open Access

The Emerging Role of Neural Cell-Derived Exosomes in Intercellular Communication in Health and Neurodegenerative Diseases.

Frontiers in Neuroscience
Luyao HuoYong Xu
September 16, 2021
Review

Extracellular Vesicles in Premature Aging and Diseases in Adulthood Due to Developmental Exposures.

Aging and Disease
Marisa R PinsonRajesh C Miranda
September 16, 2021
Review

Extracellular Vesicles for the Diagnosis and Treatment of Parkinson's Disease.

Aging and Disease
Raghavendra Upadhya, Ashok K Shetty
September 16, 2021

Loss of Christianson Syndrome Na+/H+ Exchanger 6 (NHE6) Causes Abnormal Endosome Maturation and Trafficking Underlying Lysosome Dysfunction in Neurons.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Matthew F PescosolidoEric M Morrow
September 14, 2021

A nanophytosomes formulation based on elderberry anthocyanins and Codium lipids to mitigate mitochondrial dysfunctions.

Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie
Daniela MendesRomeu A Videira
September 14, 2021
Review
Open Access

Mesenchymal Stem Cell Therapy for Alzheimer's Disease.

Stem Cells International
A E Hernández, E García
September 12, 2021
Preprint
Open Access

mTOR controls neurotoxic lysosome exocytosis in inflammatory reactive astrocytes

BioRxiv : the Preprint Server for Biology
B. RooneyMartin Kampmann
September 11, 2021

Macroautophagy and aging: The impact of cellular recycling on health and longevity.

Molecular Aspects of Medicine
Jose L Nieto-Torres, Malene Hansen
September 11, 2021
Open Access

Liraglutide ameliorates diabetes-associated cognitive dysfunction via rescuing autophagic flux.

Journal of Pharmacological Sciences
Meng ZhangLina Chen
September 9, 2021

LRRK2 along the Golgi and lysosome connection: a jamming situation.

Biochemical Society Transactions
Giovanni Piccoli, Mattia Volta

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