Neurodegeneration & Functional Genomics

Functional genomics techniques such as CRISPR/RNAi screens, microarrays, etc. can be employed to better understand complex mechanisms that underlie neurodegeneration. Here is the latest research.

July 14, 2020

Therapeutic strategies for Huntington's disease

Current Opinion in Neurology
Carlos Estevez-FragaSarah J Tabrizi
July 1, 2020

Selective Neuronal Vulnerability in Alzheimer's Disease: A Network-Based Analysis

Jean-Pierre RoussariePaul Greengard
July 22, 2020

The McGill-Mouse-Miniscope Platform: A Standardized Approach for High-throughput Imaging of Neuronal Dynamics During Behavior

Genes, Brain, and Behavior
Coralie-Anne MosserMark P Brandon
July 27, 2020

Therapeutic Update on Huntington's Disease: Symptomatic Treatments and Emerging Disease-Modifying Therapies

Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics
Deepa Dash, Tiago A Mestre
May 14, 2020

Osimertinib successfully combats EGFR-negative glioblastoma cells by inhibiting the MAPK pathway

Acta Pharmacologica Sinica
Cheng ChenQing-Song Liu
May 31, 2020
Open Access

CRISPR/Cas9-Mediated Gene Correction to Understand ALS

International Journal of Molecular Sciences
Yeomin Yun, Yoon Ha
July 31, 2020

Genes regulated by BCL11B during T-cell development are enriched for de novo mutations found in schizophrenia patients

American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics
Laura FaheyDerek W Morris
July 20, 2020

Convergence and Divergence in the Genetics of Psychiatric Disorders From Pathways to Developmental Stages

Biological Psychiatry
Shahar ShohatSagiv Shifman
May 15, 2020

Cortical cellular diversity and development in schizophrenia

Molecular Psychiatry
Amanda J PriceDaniel R Weinberger
July 14, 2020

The Use of FDG PET Parametric Imaging in the Diagnosis of Olivopontocerebellar Atrophy

Clinical Nuclear Medicine
Nassier HarfouchArnold I Brenner
June 27, 2020

Shared genetic etiology underlying late-onset Alzheimer's disease and posttraumatic stress syndrome

Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Michael W LutzOrnit Chiba-Falek
June 5, 2020

Common mutations of interest for the diagnosis of amyotrophic lateral sclerosis: how common are common mutations in ALS genes?

Expert Review of Molecular Diagnostics
Benedetta Perrone, Francesca Luisa Conforti
May 27, 2020
Open Access

Machine Learning and Multiparametric Brain MRI to Differentiate Hereditary Diffuse Leukodystrophy with Spheroids from Multiple Sclerosis

Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging
Gabriel MangeatTobias Granberg
July 8, 2020

Functional genomics links genetic origins to pathophysiology in neurodegenerative and neuropsychiatric disease

Current Opinion in Genetics & Development
Brie Wamsley, Daniel H Geschwind
July 29, 2020

Genetic Testing for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia: Impact on Clinical Management

Clinics in Laboratory Medicine
Jennifer Roggenbuck, Jamie C Fong

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