Neurodegeneration & Functional Genomics

Functional genomics techniques such as CRISPR/RNAi screens, microarrays, etc. can be employed to better understand complex mechanisms that underlie neurodegeneration. Here is the latest research.

January 14, 2022
Preprint
Open Access

Network-based integrative analysis of lithium response in bipolar disorder using transcriptomic and GWAS data

MedRxiv : the Preprint Server for Health Sciences
V. NiemsiriJ O
January 14, 2022
Review

Genetics and functional genomics of multiple sclerosis.

Seminars in Immunopathology
Woori Kim, Nikolaos A Patsopoulos
January 13, 2022

WFS1 gene associated diabetes phenotypes and identification of a founder mutation in Southern India.

The Journal of Clinical Endocrinology and Metabolism
Aaron ChaplaNihal Thomas
January 10, 2022

Latency structure of BOLD signals within white matter in resting-state fMRI.

Magnetic Resonance Imaging
Bin GuoJohn C Gore
January 11, 2022

Proteogenomics for pediatric brain cancer.

Biocell : Official Journal of the Sociedades Latinoamericanas De Microscopía Electronica ... Et. Al
Margaret Simonian
January 9, 2022
Preprint
Open Access

Structural and functional analysis of the human Cone-rod homeobox transcription factor

BioRxiv : the Preprint Server for Biology
P.-M. ClanorChristopher E Berndsen
January 8, 2022

Virus Infection of the Brain: Lessons from Drosophila for Illuminating Virus Disease and Nervous System Function.

Neuroscience
Ioannis Eleftherianos, Ghada Tafesh-Edwards
January 7, 2022

Decoding gene regulation in the fly brain.

Nature
Jasper JanssensStein Aerts
January 5, 2022
Preprint
Open Access

Transcriptional and cell type profiles of cortical brain regions showing ultradian cortisol rhythm dependent responses to emotional face stimulation

BioRxiv : the Preprint Server for Biology
Philippe C HabetsO. C. Meijer
January 6, 2022
Review

Therapy development for spinal muscular atrophy: perspectives for muscular dystrophies and neurodegenerative disorders.

Neurological Research and Practice
Sibylle JablonkaMichael Sendtner
January 4, 2022
Preprint
Open Access

The Mitochondrial RNA Granule is Necessary for Parkinsonism-Associated Metal Toxicity

BioRxiv : the Preprint Server for Biology
E. WernerVictor Faundez
January 4, 2022
Preprint
Open Access

Revealing genomic changes responsible for cannabinoid receptor loss in parrots: mechanism and functional effects

BioRxiv : the Preprint Server for Biology
D. DivinMichal Vinkler
January 3, 2022
Review

Schizophrenia Genomics: Convergence on Synaptic Development, Adult Synaptic Plasticity, or Both?

Biological Psychiatry
Jeremy Hall, Nicholas J Bray
December 31, 2021

Investigating isoform-specific functions of Tau under healthy and pathological conditions using Tau-deficient hiPSC-derived cortical neurons.

Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Sarah BachmannHans Zempel
December 31, 2021

Defective proteostasis in patient-derived iPSC-astrocytes and neurons carrying a MAPT IVS10+16 mutation.

Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Sidhartha Mahali, Celeste Karch
December 31, 2021

Identification of cis-regulatory elements associated with MAPT expression in human induced pluripotent stem cell derived neural cells.

Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Brianne B RogersJ Nicholas Cochran
December 31, 2021

Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells.

Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Samuel Walter HershTsuneya Ikezu
December 31, 2021

The Drosophila K+ -dependent Na+ /Ca2+ exchanger Nckx30C is implicated in temperature sensitive paralysis and age-dependent neurodegeneration.

Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Al Nahian Khan MajlishStanislava Chtarbanova

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