Neurodegeneration: Genetics

Neurodegeneration is the progressive loss of structure or function of neurons, including neuronal death, and leads to several diseases, including Alzheimer’s and Parkinson’s. This feed focuses on the genetic alterations that underlie neurodegeneration.

July 9, 2020

Evaluating antitumor activity of antiglypican-3 therapy in experimentally induced skin cancer in mice

Archives of Dermatological Research
Abdullah Alyoussef
July 8, 2020
Review
Open Access

Protective Mechanisms Against DNA Replication Stress in the Nervous System

Genes
Clara Forrer Charlier, Rodrigo A P Martins
July 8, 2020
Open Access

Dopaminergic neurodegeneration induced by Parkinson's disease-linked G2019S LRRK2 is dependent on kinase and GTPase activity

Proceedings of the National Academy of Sciences of the United States of America
An Phu Tran NguyenDarren J. Moore
July 9, 2020

Targeted next-generation sequencing study in familial ALS-FTD Portuguese patients negative for C9orf72 HRE

Journal of Neurology
Marta GromichoMamede de Carvalho
July 9, 2020
Review

Modern approaches in gene therapy of motor neuron diseases

Medicinal Research Reviews
Maria Zakharova
July 8, 2020
Review

An update on cellular and molecular determinants of Parkinson's disease with emphasis on the role of the retromer complex

Journal of Neuroscience Research
Vania Macías-CalvioMaría-Paz Marzolo
July 9, 2020

Emerging moonlighting functions of the branched-chain aminotransferase (BCAT) proteins

Antioxidants & Redox Signaling
Myra Elizabeth Conway
July 8, 2020
Review
Open Access

The Role of FAT10 in Alcoholic Hepatitis Pathogenesis

Biomedicines
Yue JiaSamuel W French
July 9, 2020
Review
Open Access

Astaxanthin as a Putative Geroprotector: Molecular Basis and Focus on Brain Aging

Marine Drugs
Vincenzo SorrentiDonald C Willcox
July 9, 2020

Signatures of cell stress and altered bioenergetics in skin fibroblasts from patients with multiple sclerosis

Aging
Jordan M WilkinsClaudia F Lucchinetti
July 9, 2020
Open Access

A Mixed-Surface Polyamidoamine Dendrimer for In Vitro and In Vivo Delivery of Large Plasmids

Pharmaceutics
Bhairavi SrinageshwarJulien Rossignol
July 9, 2020

Dexamethasone suppresses radicular pain through targeting L-PGDS/PI3K/Akt pathway in rats with lumbar disc herniation

Pain Practice : the Official Journal of World Institute of Pain
Weixing XuBin Xu
July 8, 2020
Open Access

The Role of Cutibacterium acnes in Intervertebral Disc Inflammation

Biomedicines
Bettina SchmidKarin Wuertz-Kozak

Sign up to follow this feed and discover related papers.

Related Feeds

AAV-based Gene Therapy

Adeno-associated virus (AAV)-based gene therapy is a biological vector that is being researched to be used as a potential therapeutic option. This gene therapy is designed to insert fragments of DNA into targeted cells to help treat diseases, such as hemophilia a. Discover the latest research on AAV-based gene therapy here.

ALS

Amyotrophic Lateral Sclerosis (ALS), also known as motor neuron disease, is associated with the death of neurons that control voluntary muscles. Discover the latest research on ALS here.

ALS & FTD: TDP-43

ALS shares with a considerable proportion of FTD cases the same neuropathological substrate, namely, inclusions of abnormally phosphorylated protein tdp-43 (ptdp-43). Here are the latest discoveries pertaining to ptdp-43 and these diseases.

ALS - Pathogenic Mechanisms

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. Here is the latest research investigating pathogenic mechanisms that underlie this genetically heterogeneous disorder.

ALS - Phenotypes

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. Here is the latest research investigating phenotypes associated with this genetically heterogeneous disorder.

ALS: Genetics

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. ALS is a genetically heterogeneous disorder with several causative genes. Here are the latest discoveries pertaining to the genetics of this disease.

ALS: Prions

Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Prion-like mechanisms are associated with the pathogenesis of Amyotrophic Lateral Sclerosis (ALS). Here are the latest discoveries pertaining to this disease.

ALS: Stress Granules

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease characterized by cytoplasmic protein aggregates within motor neurons. TDP-43 is an ALS-linked protein that is known to regulate splicing and storage of specific mRNAs into stress granules, which have been implicated in formation of ALS protein aggregates. Here is the latest research.

ALS: Therapies

Amyotrophic Lateral Sclerosis (ALS), also known as motor neuron disease, is associated with the death of neurons that control voluntary muscles. Discover the latest research on ALS therapies here.

ALS: Transposon de-silencing

Transposon silencing is a form of transcriptional gene silencing. These gene silencing mechanisms are impaired in Amyotrophic lateral sclerosis (ALS). Here are the latest discoveries pertaining to transposon silencing and this disease.

© 2020 Meta ULC. All rights reserved
/feed-previews/neurodegeneration-genetics/943564d3-97cb-4a6e-8c78-f547229e8746