Neurodegeneration: Genetics

Neurodegeneration is the progressive loss of structure or function of neurons, including neuronal death, and leads to several diseases, including Alzheimer’s and Parkinson’s. This feed focuses on the genetic alterations that underlie neurodegeneration.

October 16, 2020
Preprint
Open Access

Multi-omics integration analysis identifies novel genes for alcoholism with potential link to neurodegenerative diseases

BioRxiv : the Preprint Server for Biology
Manav KapoorA. M. Goate
October 13, 2020
Review
Open Access

The Emerging Role of RHOT1 /Miro1 in the Pathogenesis of Parkinson's Disease

Frontiers in Neurology
Dajana GrossmannRejko Krüger
October 13, 2020
Preprint
Open Access

Sex-Specific Cross Tissue Meta-Analysis Identifies Immune Dysregulation in Women with Alzheimer's Disease

ResearchSquare
Manish D ParanjpeMarina Sirota
October 12, 2020
Preprint
Open Access

A dominant-negative variant in the dopamine transporter PDZ-binding motif is linked to parkinsonism and neuropsychiatric disease

BioRxiv : the Preprint Server for Biology
Freja HerborgU. Gether
October 14, 2020
Preprint
Open Access

Neuronal NOX4 knockdown alleviates pathological tau-related alterations in a humanized mouse model of tauopathy

BioRxiv : the Preprint Server for Biology
E. LuengoManuela G Lopez
October 14, 2020
Open Access

Xeno- and transgene-free reprogramming of mesenchymal stem cells toward the cells expressing neural markers using exosome treatments

PloS One
Luis Sebástian Alexis Valerio, Kiminobu Sugaya
October 13, 2020
Case Report

Facial Dysmorphism, Hirsutism, and Failure to Thrive as Manifestation of Leigh Syndrome in a Child with SURF1 Mutation

Journal of Pediatric Neurosciences
Dhinesh Baskaran, Nahin Hussain
October 14, 2020
Open Access

Ectopic fat accumulation in human astrocytes impairs insulin action

Royal Society Open Science
Martin HeniHarald Staiger
October 14, 2020

Identifying potential gene biomarkers for Parkinson's disease through an information entropy based approach

Physical Biology
Alfonso MonacoRoberto Bellotti
October 13, 2020

KIT gene mutation causes deafness and hypopigmentation in Bama miniature pigs

American Journal of Translational Research
Cong XuShiming Yang
October 13, 2020

Identification of a peripheral blood gene signature predicting aortic valve calcification

Physiological Genomics
Donal MacGroganJosé Luis de la Pompa
October 14, 2020

Double-stranded RNA-induced dopaminergic neuronal loss in the substantia nigra in the presence of Mac1 receptor

Biochemical and Biophysical Research Communications
Weixing XuJing Huang
October 16, 2020
Preprint
Open Access

RTP801 Is A Key Modulator For Motor Learning

BioRxiv : the Preprint Server for Biology
L. Perez-SisquesCristina Malagelada
October 13, 2020
Review
Open Access

Good problems to have? Policy and societal implications of a disease-modifying therapy for presymptomatic late-onset Alzheimer's disease

Life Sciences, Society and Policy
Misha AngristOrnit Chiba-Falek
October 14, 2020

Synthesis, binding, and functional properties of tetrahydroisoquinolino-2-alkyl phenones as selective σ2 R/TMEM97 ligands

European Journal of Medicinal Chemistry
Xiao-Yang XieYun-Sheng Huang
October 14, 2020

Osteoarthritis of facet and sacroiliac joints

Ugeskrift for laeger
Mikkel Østerheden AndersenHans Christian Horn

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