Neurodegeneration: Genetics

Neurodegeneration is the progressive loss of structure or function of neurons, including neuronal death, and leads to several diseases, including Alzheimer’s and Parkinson’s. This feed focuses on the genetic alterations that underlie neurodegeneration.

December 7, 2021
Review

Microglial TREM2 in amyotrophic lateral sclerosis.

Developmental Neurobiology
Manling XieLong-Jun Wu
December 7, 2021

Identification of cyclin D1 as a major modulator of 3-nitropropionic acid-induced striatal neurodegeneration.

Neurobiology of Disease
Paula DietrichIoannis Dragatsis
December 7, 2021

Novel Machado-Joseph disease-modifying genes and pathways identified by whole-exome sequencing.

Neurobiology of Disease
Mafalda RaposoManuela Lima
December 7, 2021

Multi-omic insights into Parkinson's Disease: From genetic associations to functional mechanisms.

Neurobiology of Disease
Brian M SchilderTowfique Raj
December 6, 2021
Preprint
Open Access

Tracing the genetics of neurological disease to the mutation-directed addition of single hydrogen bonds

BioRxiv : the Preprint Server for Biology
x. zhouS. McKnight
December 6, 2021

Altered protein secretion in Batten disease.

Disease Models & Mechanisms
Robert J Huber
December 6, 2021
Open Access

Neurotoxin-mediated --potent activation of the axon degeneration regulator SARM1.

ELife
Andrea LoretoMichael P Coleman
December 6, 2021

Amyotrophic lateral sclerosis associated with a pathological expansion in the ATXN7 gene.

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration
Florent CluseAntoine Pegat
December 6, 2021
Comment / Editorial
Open Access

Editorial: The Dynamics of Stress Granules.

Frontiers in Cell and Developmental Biology
Subhash MehtoSantosh Chauhan
December 6, 2021
Open Access

Starvation to Glucose Reprograms Development of Neurovascular Unit in Embryonic Retinal Cells.

Frontiers in Cell and Developmental Biology
Türküler ÖzgümüsValeriya Lyssenko
December 6, 2021

Cyclodextrin-Appended Superparamagnetic Iron Oxide Nanoparticles as Cholesterol-Mopping Agents.

Frontiers in Chemistry
Antonino PuglisiErik Reimhult
December 6, 2021
Review
Open Access

Carbonic Anhydrases as Potential Targets Against Neurovascular Unit Dysfunction in Alzheimer's Disease and Stroke.

Frontiers in Aging Neuroscience
Nicole LemonSilvia Fossati
December 6, 2021
Comment / Editorial
Open Access

Editorial: Neurodegeneration: From Genetics to Molecules (Part II).

Frontiers in Cellular Neuroscience
Karla Guadalupe CarvajalVictoria Campos-Peña
December 6, 2021
Review
Open Access

Exploration of Aberrant E3 Ligases Implicated in Alzheimer's Disease and Development of Chemical Tools to Modulate Their Function.

Frontiers in Cellular Neuroscience
Frances M Potjewyd, Alison D Axtman
December 6, 2021
Open Access

Disease Duration Influences Gene Expression in Neuromelanin-Positive Cells From Parkinson's Disease Patients.

Frontiers in Molecular Neuroscience
Katarína TiklováThomas Perlmann
December 6, 2021
Review
Open Access

The Role of Mitochondria in Optic Atrophy With Autosomal Inheritance.

Frontiers in Neuroscience
Elin L StrachanNiamh C O'Sullivan

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