Neurodegeneration: Therapeutic Targets

Neurodegeneration is the progressive loss of structure or function of neurons, including neuronal death, and leads to several diseases, including Alzheimer’s and Parkinson’s. This feed focuses on therapeutic targets for neurodegenerative disorders.

November 11, 2019
Review

DNA double-strand breaks: a potential therapeutic target for neurodegenerative diseases

Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology
Nidheesh ThadathilMohammad Moshahid Khan
March 14, 2020
Review
Open Access

Protein Phosphatase 2A as a Drug Target in the Treatment of Cancer and Alzheimer's Disease

Current Medical Science
Hui WeiRong Liu
July 12, 2019
Case Report
Open Access

Atopic Dermatitis-Like Rash During Evolocumab Treatment of Familial Hypercholesterolemia

Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi
Naoko Kanda, Fumitaka Okajima
April 17, 2019
Review

Sequestosome 1/p62-related pathways as therapeutic targets in hepatocellular carcinoma

Expert Opinion on Therapeutic Targets
Helmut DenkKurt Zatloukal
June 23, 2019
Open Access

Recent advances in molecular therapies for neurological disease: triplet repeat disorders

Human Molecular Genetics
Pedro Gonzalez-Alegre
November 21, 2019

Destabilization of β-amyloid aggregates by thrombin derived peptide: plausible role of thrombin in neuroprotection

The FEBS Journal
Debashree DeDebasish Bhattacharyya
June 28, 2019

The Outliers: Metal-Mediated Radical Reagents for Biological Substrate Degradation

Accounts of Chemical Research
Meghan R PorterJeffrey M Zaleski
April 20, 2020
Review
Open Access

Cathepsin B in neurodegeneration of Alzheimer's disease, traumatic brain injury, and related brain disorders

Biochimica Et Biophysica Acta. Proteins and Proteomics
Vivian HookGregory Hook
June 9, 2020
Open Access

Inhibition of STAT3 phosphorylation attenuates impairments in learning and memory in 5XFAD mice, an animal model of Alzheimer's disease

Journal of Pharmacological Sciences
Moonseok ChoiHye-Sun Kim
May 12, 2020
Review

Inherited disorders of lysosomal membrane transporters

Biochimica Et Biophysica Acta. Biomembranes
Marjan Huizing, William A Gahl
September 27, 2019
Review
Open Access

A New Kid on the Block? Carbonic Anhydrases as Possible New Targets in Alzheimer's Disease

International Journal of Molecular Sciences
Gustavo ProvensiSilvia Fossati
December 17, 2019
Review
Open Access

Tau as a potential therapeutic target for ischemic stroke

Aging
Xin Chen, Hua Jiang
December 8, 2019
Review
Open Access

Mechanisms of immune evasion in bladder cancer

Cancer Immunology, Immunotherapy : CII
Paul L Crispen, Sergei Kusmartsev
June 5, 2019
Review

Recent Developments in LRRK2-Targeted Therapy for Parkinson's Disease

Drugs
Ye Zhao, Nicolas Dzamko
November 22, 2019
Open Access

Vitamin K1 As A Potential Molecule For Reducing Single-Walled Carbon Nanotubes-Stimulated α-Synuclein Structural Changes And Cytotoxicity

International Journal of Nanomedicine
Amitis NaskhiMojtaba Falahati
October 16, 2019
Review
Open Access

Clinical drug development for dementia with Lewy bodies: past and present

Expert Opinion on Investigational Drugs
Garam LeeMarwan Noel Sabbagh
June 19, 2019
Review
Open Access

Roles of the M4 acetylcholine receptor in the basal ganglia and the treatment of movement disorders

Movement Disorders : Official Journal of the Movement Disorder Society
Mark S Moehle, P Jeffrey Conn

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