Neurodegenerative Disease: Genetics & Pathology

A possible barrier to the study of neurodegenerative disorders is the lack of human-relevant models. This feed includes research on transcriptomics and pathology in neurodegenerative disease.

August 3, 2020

Neuroinflammation and histone H3 citrullination are increased in X-linked Dystonia Parkinsonism post-mortem prefrontal cortex

Neurobiology of Disease
Tiziana PetrozzielloGhazaleh Sadri-Vakili
July 23, 2020

Peripheral inflammation exacerbates α-synuclein toxicity and neuropathology in Parkinson's models

Neuropathology and Applied Neurobiology
Pietro La VitolaGianluigi Forloni
August 3, 2020

Clinical Presentation of Chronic Traumatic Encephalopathy

Seminars in Neurology
Megan MarianiRobert A Stern
July 17, 2020
Open Access

MicroRNA-223 Regulates Retinal Function and Inflammation in the Healthy and Degenerating Retina

Frontiers in Cell and Developmental Biology
Nilisha FernandoRiccardo Natoli
August 1, 2020
Review
Open Access

Midbrain Dopaminergic Neuron Development at the Single Cell Level: In vivo and in Stem Cells

Frontiers in Cell and Developmental Biology
Emilía Sif Ásgrímsdóttir, Ernest Arenas
August 3, 2020

CD8+ T cells are increased in the subventricular zone with physiological and pathological aging

Aging Cell
Manuel Moreno-ValladaresAnder Matheu
July 30, 2020
Open Access

Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders

JAMA : the Journal of the American Medical Association
Sebastian PalmqvistOskar Hansson
July 29, 2020
Preprint

Genotype and defects in microtubule-based motility correlate with clinical severity in KIF1A Associated Neurological Disorder

MedRxiv : the Preprint Server for Health Sciences
L. BoyleWendy K Chung
July 31, 2020
Review
Open Access

Amburana cearensis : Pharmacological and Neuroprotective Effects of Its Compounds

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Juliana Helena Castro E SilvaSilvia Lima Costa
July 28, 2020

The Neuropathology of Chronic Traumatic Encephalopathy: The Status of the Literature

Seminars in Neurology
Ann C McKee
July 28, 2020
Preprint
Open Access

Systemic inflammation causes microglial dysfunction with a mixed AD-like pathology.

BioRxiv : the Preprint Server for Biology
P. BathiniLavinia Alberi
July 28, 2020
Review
Open Access

From Riluzole to Dexpramipexole via Substituted-Benzothiazole Derivatives for Amyotrophic Lateral Sclerosis Disease Treatment: Case Studies

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Serge MignaniGiovanni Lentini
July 30, 2020

Brain insulin resistance impairs hippocampal plasticity

Vitamins and Hormones
Matteo SpinelliClaudio Grassi
August 1, 2020
Review

Circadian alterations in patients with neurodegenerative diseases: Neuropathological basis of underlying network mechanisms

Neurobiology of Disease
Karim Fifel, Aleksandar Videnovic
July 27, 2020
Open Access

Trem2 deficiency differentially affects phenotype and transcriptome of human APOE3 and APOE4 mice

Molecular Neurodegeneration
Nicholas F FitzRadosveta Koldamova
August 1, 2020
Preprint

Multiplexed fractionated proteomics reveals synaptic factors associated with cognitive resilience in Alzheimer's Disease

BioRxiv : the Preprint Server for Biology
Becky Catherine CarlyleS. E. Arnold

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