Neurodegenerative Disease & Obesity

Neurodegenerative disorders and obesity appear to have common pathologies including neuroinflammation. Targeting common pathways may prove to be a useful treatment strategy for neurodegenerative disease. Discover the latest research on neurodegenerative disorders and obesity here.

January 20, 2021
Open Access

Overweight/obesity in young adulthood interacts with aspects of EBV infection in MS etiology.

Neurology. Neuroimmunology and Neuroinflammation
Anna Karin HedströmLars Alfredsson
January 5, 2021

Small Molecule Inhibitors Targeting Biosynthesis of Ceramide, the Central Hub of the Sphingolipid Network

Journal of Medicinal Chemistry
Jan SkácelTakashi Tsukamoto
December 31, 2020
Review
Open Access

Neuroprotective Effects of Coffee Bioactive Compounds: A Review

International Journal of Molecular Sciences
Katarzyna SocałaPiotr Wlaź
January 17, 2021

Agomelatine effects on fat-enriched diet induced neuroinflammation and depression-like behavior in rats.

Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie
Redouane RebaiAbdennacer Boudah
January 6, 2021
Review

Dysbiosis and Alzheimer's Disease: Cause or Treatment Opportunity?

Cellular and Molecular Neurobiology
Manuel H JaneiroMaite Solas
December 29, 2020

Association between facet joint orientation/tropism and lumbar intervertebral disc degeneration

British Journal of Neurosurgery
Murat Şakir EkşiM Necmettin Pamir
January 4, 2021

Lipoxygenase (LOX) Pathway: A Promising Target to Combat Cancer

Current Pharmaceutical Design
Vishnupriya P Vijaya Padma V
January 14, 2021
Comment / Editorial
Open Access

Obesity's role in MS: An intervention target with possible interactions.

Neurology. Neuroimmunology and Neuroinflammation
Kathryn C Fitzgerald, Ellen M Mowry
January 21, 2021
Review
Open Access

Beneficial Effects of Epigallocatechin-3-O-Gallate, Chlorogenic Acid, Resveratrol, and Curcumin on Neurodegenerative Diseases.

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Ryuuta FukutomiMamoru Isemura
January 9, 2021
Review
Open Access

Role of Sirtuins in Modulating Neurodegeneration of the Enteric Nervous System and Central Nervous System

Frontiers in Neuroscience
Pavithra ChandramowlishwaranShanthi Srinivasan
January 3, 2021

Plant miR171 modulates mTOR pathway in HEK293 cells by targeting GNA12

Molecular Biology Reports
Angelo GismondiAntonella Canini
January 23, 2021
Review

Global pandemics interconnected - obesity, impaired metabolic health and COVID-19.

Nature Reviews. Endocrinology
Norbert StefanMatthias B Schulze
January 24, 2021
Open Access

Protective effect of grape seed extract and orlistat co-treatment against stroke: Effect on oxidative stress and energy failure.

Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie
Safwen KadriMeherzia Mokni
January 25, 2021

Hydrogen as a Potential Therapeutic in Obesity: Targeting the Brain.

Trends in Endocrinology and Metabolism : TEM
Sergej M Ostojic
January 1, 2021
Review
Open Access

From Obesity to Hippocampal Neurodegeneration: Pathogenesis and Non-Pharmacological Interventions

International Journal of Molecular Sciences
Thomas Ho-Yin Lee, Suk-Yu Yau
January 6, 2021

Nicotinamide as a Foundation for Treating Neurodegenerative Disease and Metabolic Disorders

Current Neurovascular Research
Kenneth Maiese
January 9, 2021
Open Access

AgRP neurons trigger long-term potentiation and facilitate food seeking.

Translational Psychiatry
Chunmei WangYong Xu

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