Neurogenetics of Alternative Splicing

Alternative splicing is a regulated gene expression process that allows a single genetic sequence to code for multiple proteins. Dysregulation of alternative splicing can lead to developmental defects and can play a role in some neurological disorders. Here is that latest research.

August 2, 2020
Open Access

The atlas of RNase H antisense oligonucleotide distribution and activity in the CNS of rodents and non-human primates following central administration

BioRxiv : the Preprint Server for Biology
Frank RigoP. Narayanan
September 28, 2018

Emerging Role of Circular RNAs as Potential Biomarkers for the Diagnosis of Human Diseases

Advances in Experimental Medicine and Biology
Rupal OjhaVijay Kumar Prajapati
January 13, 2019

Methods for Annotation and Validation of Circular RNAs from RNAseq Data

Methods in Molecular Biology
Disha SharmaVinod Scaria
October 29, 2018

Lowry-Wood syndrome: further evidence of association with RNU4ATAC, and correlation between genotype and phenotype

Human Genetics
Ivan ShelihanPhilippe M Campeau
October 12, 2018
Open Access

A Dimeric 2,9-Diamino-1,10-phenanthroline Derivative Improves Alternative Splicing in Myotonic Dystrophy Type 1 Cell and Mouse Models

Chemistry : a European Journal
Jinxing LiKazuhiko Nakatani
June 27, 2020
Open Access

Regional Variation of Splicing QTLs in Human Brain

American Journal of Human Genetics
Yida ZhangYi Xing
September 28, 2018

Circular RNAs in Cardiovascular Diseases

Advances in Experimental Medicine and Biology
Lijun WangJunjie Xiao
December 4, 2019

A transcriptomic analysis of Nsmce1 overexpression in mouse hippocampal neuronal cell by RNA sequencing

Functional & Integrative Genomics
Mengting GongKan He
August 8, 2020
Open Access

Innovative Therapeutic and Delivery Approaches Using Nanotechnology to Correct Splicing Defects Underlying Disease

Frontiers in Genetics
Marc Suñé-PouCarlos Suñé
February 27, 2020
Open Access

Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information

Nature Communications
Sebastian GuelfiMina Ryten
February 21, 2019
Open Access

Circular RNA biogenesis is decreased in postmortem cortical gray matter in schizophrenia and may alter the bioavailability of associated miRNA

Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
Ebrahim MahmoudiMurray J Cairns
June 15, 2020

Microexons: at the nexus of nervous system development, behaviour and autism spectrum disorder

Current Opinion in Genetics & Development
Thomas Gonatopoulos-Pournatzis, Benjamin J Blencowe
March 28, 2019
Open Access

Regulatory sites for known and novel splicing in human basal ganglia are enriched for disease-relevant information

BioRxiv : the Preprint Server for Biology
Sebastian GuelfiMina Ryten
September 8, 2020

Biogenesis of circular RNAs and their role in cellular and molecular phenotypes of neurological disorders

Seminars in Cell & Developmental Biology
B S GuerraR H Herai
July 12, 2020

De novo mutation and skewed X-inactivation in girl with BCAP31-related syndrome

Human Mutation
Hsiao-Jung KaoNi-Chung Lee
November 4, 2019

Does Circular RNA Exert Significant Effects in Ovarian Cancer?

Critical Reviews in Eukaryotic Gene Expression
Ying FengZhenyu Zhang

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