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Neurogenetics of Alternative Splicing

Neurogenetics of Alternative Splicing diagram by Public Domain, Wikimedia
Public Domain, Wikimedia

Alternative splicing is a regulated gene expression process that allows a single genetic sequence to code for multiple proteins. Dysregulation of alternative splicing can lead to developmental defects and can play a role in some neurological disorders. Here is that latest research.

Top 20 most recent papers
Scientific Reports

Alternatively spliced isoforms reveal a novel type of PTB domain in CCM2 protein

Scientific ReportsNovember 4, 2019
Xiaoting JiangJun Zhang
bioRxiv

ACTOR: a latent Dirichlet model to compare expressed isoform proportions to a reference panel

bioRxivNovember 26, 2019
Sean D. McCabeMichael I Love
35
bioRxiv

LincRNAs involved in DCS-induced fear extinction: Shedding light on the transcriptomic dark matter

bioRxivNovember 8, 2019
Stefanie Malan-MullerSian M.J Hemmings
5
bioRxiv

Differences in splicing defects between the grey and white matter in myotonic dystrophy type 1

bioRxivOctober 25, 2019
Masamitsu NishiHiroo Yoshikawa
1
4
Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics

Myotonic Dystrophies: Targeting Therapies for Multisystem Disease

Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeuticsOctober 21, 2018
Samantha LoRussoW David Arnold
5
30
bioRxiv

Regulatory sites for known and novel splicing in human basal ganglia are enriched for disease-relevant information

bioRxivMarch 28, 2019
Sebastian GuelfiMina Ryten
11
10
Journal of Neurology

Novel NAXE variants as a cause for neurometabolic disorder: implications for treatment

Journal of NeurologyNovember 21, 2019
Joanne TrinhNorbert Brüggemann
Molecular Cell

Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons

Molecular CellNovember 3, 2018
Thomas Gonatopoulos-PournatzisBenjamin J Blencowe
106
5
110
1
Methods in Molecular Biology

Methods for Annotation and Validation of Circular RNAs from RNAseq Data

Methods in Molecular BiologyJanuary 13, 2019
Disha SharmaVinod Scaria
13
Genes

Genome-Wide Association Study and Subsequent Exclusion of ATCAY as a Candidate Gene Involved in Equine Neuroaxonal Dystrophy Using Two Animal Models

GenesJanuary 16, 2020
Erin N HalesCarrie J Finno
Cerebral Cortex

Temporal Dynam ics of the Neuregulin-ErbB Network in the Murine Prefrontal Cortex across the Lifespan

Cerebral CortexJanuary 4, 2020
Clare PatersonAmanda J Law
Genes & Diseases

The novel roles of circular RNAs in metabolic organs

Genes & DiseasesSeptember 28, 2018
Zhi-Chun ZhangXi Li
1
24
American Journal of Human Genetics

Mutations in PIGS, Encoding a GPI Transamidase, Cause a Neurological Syndrome Ranging from Fetal Akinesia to Epileptic Encephalopathy

American Journal of Human GeneticsOctober 2, 2018
Thi Tuyet Mai NguyenPhilippe M Campeau
3
19
Genes & Development

The microtubule regulator ringer functions downstream from the RNA repair/splicing pathway to promote axon regeneration

Genes & DevelopmentJanuary 11, 2020
Ernest J Monahan VargasYuanquan Song
8
Frontiers in Genetics

Recent Insights Into the Structure, Function, and Evolution of the RNA-Splicing Endonucleases

Frontiers in GeneticsFebruary 28, 2019
Akira Hirata
3
6
ACS Chemical Neuroscience

Electron Acceptive Mass Tag for Mass Spectrometric Imaging-Guided Synergistic Targeting to Mice Brain Glutamate Receptors

ACS Chemical NeuroscienceDecember 23, 2018
Ruowei JiangHongying Zhong
3
4
Journal of Translational Medicine

RNA editing in the forefront of epitranscriptomics and human health

Journal of Translational MedicineSeptember 25, 2019
Theodoulakis Christofi, Apostolos Zaravinos
Frontiers in Neuroscience

Latrophilins: A Neuro-Centric View of an Evolutionary Conserved Adhesion G Protein-Coupled Receptor Subfamily

Frontiers in NeuroscienceJuly 30, 2019
Ana L Moreno-SalinasAntony A Boucard
14
12
Annals of the New York Academy of Sciences

Small molecule targeting of RNA structures in neurological disorders

Annals of the New York Academy of SciencesApril 10, 2019
Alicia J AngelbelloMatthew D Disney
39
1
15
Biological Chemistry

The microtubule skeleton and the evolution of neuronal complexity in vertebrates

Biological ChemistryMay 23, 2019
Nataliya I TrushinaRoland Brandt
2
9

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