Neurogenetics of Alternative Splicing

Alternative splicing is a regulated gene expression process that allows a single genetic sequence to code for multiple proteins. Dysregulation of alternative splicing can lead to developmental defects and can play a role in some neurological disorders. Here is that latest research.

September 18, 2018
Open Access

Depletion of Nesprin-2 is associated with an embryonic lethal phenotype in mice

Nucleus
Carmen MroßSascha Neumann
September 28, 2018
Review

Emerging Role of Circular RNAs as Potential Biomarkers for the Diagnosis of Human Diseases

Advances in Experimental Medicine and Biology
Rupal OjhaVijay Kumar Prajapati
January 13, 2019

Methods for Annotation and Validation of Circular RNAs from RNAseq Data

Methods in Molecular Biology
Disha SharmaVinod Scaria
March 4, 2020

Unraveling mechanisms of patient-specific NRXN1 mutations in neuropsychiatric diseases using human induced Pluripotent Stem cells

Stem Cells and Development
Alejandro De Los Angeles, Elizabeth M Tunbridge
June 27, 2020

Regional Variation of Splicing QTLs in Human Brain

American Journal of Human Genetics
Yida ZhangYi Xing
September 28, 2018
Review

Circular RNAs in Cardiovascular Diseases

Advances in Experimental Medicine and Biology
Lijun WangJunjie Xiao
December 4, 2019

A transcriptomic analysis of Nsmce1 overexpression in mouse hippocampal neuronal cell by RNA sequencing

Functional & Integrative Genomics
Mengting GongKan He
February 27, 2020
Open Access

Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information

Nature Communications
Sebastian GuelfiMina Ryten
August 19, 2018
Open Access

Identifying SYNE1 ataxia and extending the mutational spectrum in Korea

Parkinsonism & Related Disorders
Ji Sun KimJin Whan Cho
February 21, 2019

Circular RNA biogenesis is decreased in postmortem cortical gray matter in schizophrenia and may alter the bioavailability of associated miRNA

Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
Ebrahim MahmoudiMurray J Cairns
June 15, 2020
Review

Microexons: at the nexus of nervous system development, behaviour and autism spectrum disorder

Current Opinion in Genetics & Development
Thomas Gonatopoulos-Pournatzis, Benjamin J Blencowe
March 28, 2019
Open Access

Regulatory sites for known and novel splicing in human basal ganglia are enriched for disease-relevant information

BioRxiv : the Preprint Server for Biology
Sebastian GuelfiMina Ryten
September 22, 2018
Open Access

Improved ontology for eukaryotic single-exon coding sequences in biological databases

Database : the Journal of Biological Databases and Curation
Roddy JorqueraDavid S Holmes
November 4, 2019
Review

Does Circular RNA Exert Significant Effects in Ovarian Cancer?

Critical Reviews in Eukaryotic Gene Expression
Ying FengZhenyu Zhang

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