Feed Preview

Neurogenetics of Alternative Splicing

Neurogenetics of Alternative Splicing diagram by Public Domain, Wikimedia
Public Domain, Wikimedia

Alternative splicing is a regulated gene expression process that allows a single genetic sequence to code for multiple proteins. Dysregulation of alternative splicing can lead to developmental defects and can play a role in some neurological disorders. Here is that latest research.

Top 20 most recent papers
Scientific Reports

Alternatively spliced isoforms reveal a novel type of PTB domain in CCM2 protein

Scientific ReportsNovember 4, 2019
Xiaoting JiangJun Zhang

ACTOR: a latent Dirichlet model to compare expressed isoform proportions to a reference panel

bioRxivNovember 26, 2019
Sean D. McCabeMichael I Love

LincRNAs involved in DCS-induced fear extinction: Shedding light on the transcriptomic dark matter

bioRxivNovember 8, 2019
Stefanie Malan-MullerSian M.J Hemmings

Differences in splicing defects between the grey and white matter in myotonic dystrophy type 1

bioRxivOctober 25, 2019
Masamitsu NishiHiroo Yoshikawa
Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics

Myotonic Dystrophies: Targeting Therapies for Multisystem Disease

Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeuticsOctober 21, 2018
Samantha LoRussoW David Arnold

Regulatory sites for known and novel splicing in human basal ganglia are enriched for disease-relevant information

bioRxivMarch 28, 2019
Sebastian GuelfiMina Ryten
Journal of Neurology

Novel NAXE variants as a cause for neurometabolic disorder: implications for treatment

Journal of NeurologyNovember 21, 2019
Joanne TrinhNorbert Brüggemann
Molecular Cell

Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons

Molecular CellNovember 3, 2018
Thomas Gonatopoulos-PournatzisBenjamin J Blencowe
Methods in Molecular Biology

Methods for Annotation and Validation of Circular RNAs from RNAseq Data

Methods in Molecular BiologyJanuary 13, 2019
Disha SharmaVinod Scaria

Genome-Wide Association Study and Subsequent Exclusion of ATCAY as a Candidate Gene Involved in Equine Neuroaxonal Dystrophy Using Two Animal Models

GenesJanuary 16, 2020
Erin N HalesCarrie J Finno
Cerebral Cortex

Temporal Dynam ics of the Neuregulin-ErbB Network in the Murine Prefrontal Cortex across the Lifespan

Cerebral CortexJanuary 4, 2020
Clare PatersonAmanda J Law
Genes & Diseases

The novel roles of circular RNAs in metabolic organs

Genes & DiseasesSeptember 28, 2018
Zhi-Chun ZhangXi Li
American Journal of Human Genetics

Mutations in PIGS, Encoding a GPI Transamidase, Cause a Neurological Syndrome Ranging from Fetal Akinesia to Epileptic Encephalopathy

American Journal of Human GeneticsOctober 2, 2018
Thi Tuyet Mai NguyenPhilippe M Campeau
Genes & Development

The microtubule regulator ringer functions downstream from the RNA repair/splicing pathway to promote axon regeneration

Genes & DevelopmentJanuary 11, 2020
Ernest J Monahan VargasYuanquan Song
Frontiers in Genetics

Recent Insights Into the Structure, Function, and Evolution of the RNA-Splicing Endonucleases

Frontiers in GeneticsFebruary 28, 2019
Akira Hirata
ACS Chemical Neuroscience

Electron Acceptive Mass Tag for Mass Spectrometric Imaging-Guided Synergistic Targeting to Mice Brain Glutamate Receptors

ACS Chemical NeuroscienceDecember 23, 2018
Ruowei JiangHongying Zhong
Journal of Translational Medicine

RNA editing in the forefront of epitranscriptomics and human health

Journal of Translational MedicineSeptember 25, 2019
Theodoulakis Christofi, Apostolos Zaravinos
Frontiers in Neuroscience

Latrophilins: A Neuro-Centric View of an Evolutionary Conserved Adhesion G Protein-Coupled Receptor Subfamily

Frontiers in NeuroscienceJuly 30, 2019
Ana L Moreno-SalinasAntony A Boucard
Annals of the New York Academy of Sciences

Small molecule targeting of RNA structures in neurological disorders

Annals of the New York Academy of SciencesApril 10, 2019
Alicia J AngelbelloMatthew D Disney
Biological Chemistry

The microtubule skeleton and the evolution of neuronal complexity in vertebrates

Biological ChemistryMay 23, 2019
Nataliya I TrushinaRoland Brandt

See more papers from this feed

Related Feeds

ALS: Genetics

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. ALS is a genetically heterogeneous disorder with several causative genes. Here are the latest discoveries pertaining to the genetics of this disease.

Cognitive Decline: Environmental And Genetic Factors

This feed focuses on the role of environmental and genetic factors including environmental policies, disease susceptibility, and socioeconomic status on cognitive decline. Here is the latest research.

Epigenetic Changes in Pain

Targeted epigenetic interventions provide the tools to prevent nociceptive sensitization, mood-related symptoms, and other adaptations that occur in response to injury or inflammation, which will facilitate pain management and improve treatment efficacy in many chronic pain conditions. Here is the latest research on the epigenetics changes in pain.

Epigenetic Regulation of Microglia Functions

Microglial cells are instrumental in the maintenance of homeostasis in the CNS and can contribute to neurodegenerative disorders. Epigenetic mechanisms and transcriptional regulation may be potential therapeutic targets for their activation or suppression. Discover the latest research on epigenetic regulation of microglial functions here.

Gene-Environment Interaction & Behaviour

Gene-environment interaction is when two different genotypes respond to environmental variation in different ways.Genes and environment interact to form an individual's personality. Abnormal or extreme behaviour could thus be explained by hereditary factors in combination with poor environmental conditions.

Genetic Influences on Brain Development

The genetic landscape of an individual can have drastic effects on brain development and brain developmental disorders. Discover the latest research here.

Genetic Networks Underlying Habituation

Habituation, the gradual waning of an evoked behavioral response with repeated stimulation, is a basic and universal form of learning. This feed explores the genetic networks that are involved in the occurence of habituation.

Genetic Screens in iPSC-Derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.

Genetics of Pain

Subtle changes in DNA could partly explain the variation in individual differences in pain. There is growing evidence that a number of genes play a critical role in determining pain sensitivity, pain reporting and susceptibility to developing chronic pain and their response to surgical outcomes primarily, pain.

Immunogenetics of CNS Tumors

Central nervous system (CNS) tumors have a unique tumor immune microenvironment, where immune cells can play a role in disease progression and resistance to therapy. Studying the immunogenetics of these cells can uncover mechanisms underlying their role in CNS tumors. Here is the latest research.

© 2020 Meta ULC. All rights reserved