Neuronal Tyrosine Kinase Receptors

The binding of neurotropic factors activates tyrosine kinase receptors in both central and peripheral neurons. This signals the correct location, morphology, and integration of neurons into the vast neural network. Discover the latest research of neuronal tyrosine kinase receptors here.

January 21, 2022

High-affinity TrkA and p75 neurotrophin receptor complexes: a twisted affair.

The Journal of Biological Chemistry
Jacinta N Conroy, Elizabeth J Coulson
January 21, 2022
Open Access

Understanding the development of oral epithelial organs through single cell transcriptomic analysis

BioRxiv : the Preprint Server for Biology
Q. YeJimmy K. Hu
January 19, 2022

Genetic Analysis of Pediatric Pancreatoblastoma: A Case Report.

Zhengzheng WangJinxue Zhou
January 17, 2022
Case Report

A Unique Case Report of Infant-Type Hemispheric Glioma (Gliosarcoma Subtype) with TPR-NTRK1 Fusion Treated with Larotrectinib.

Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology
Bruna Minniti MançanoRui Manuel Reis
January 12, 2022

Activation of neurotrophin signalling with light‑inducible receptor tyrosine kinases.

Molecular Medicine Reports
Wei ZhangShixin Ye
January 12, 2022

Fusion Oncogenes Are Associated With Increased Metastatic Capacity and Persistent Disease in Pediatric Thyroid Cancers.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Aime T FrancoAndrew J Bauer
January 11, 2022

Pan-tumor screening for NTRK gene fusions using pan-TRK immunohistochemistry and RNA NGS fusion panel testing.

Cancer Genetics
Anne Koehne de GonzálezSusan J Hsiao
January 9, 2022
Open Access

Oncogenic role of a developmentally regulated NTRK2 splice variant

BioRxiv : the Preprint Server for Biology
Siobhan S PattwellE. C. Holland
January 1, 2022

NTRK point mutations and their functional consequences.

Cancer Genetics
Corey RogersRobyn T Sussman
December 29, 2021
Open Access

Ret loss-of-function decreases enteric neural crest progenitor proliferation and restricts developmental fate potential during enteric nervous system development

BioRxiv : the Preprint Server for Biology
E. VincentLoyal A Goff
December 28, 2021
Open Access

Developmental Disruption of Erbb4 in Pet1+ Neurons Impairs Serotonergic Sub-System Connectivity and Memory Formation.

Frontiers in Cell and Developmental Biology
Candela BarettinoIsabel Del Pino
December 28, 2021

Sustained experimental activation of FGF8/ERK in the developing chicken spinal cord models early events in ERK-mediated tumorigenesis.

Neoplasia : an International Journal for Oncology Research
Axelle WilmerdingMarie-Claire Delfini
December 25, 2021
Open Access

Live-Cell Imaging of Single Neurotrophin Receptor Molecules on Human Neurons in Alzheimer's Disease.

International Journal of Molecular Sciences
Klaudia BarabásIstván M Ábrahám
December 23, 2021
Open Access

Investigation of a Novel NTRK1 Variation Causing Congenital Insensitivity to Pain With Anhidrosis.

Frontiers in Genetics
Kai YangCheng-Hong Yin
December 15, 2021

Early Induction of Neurotrophin Receptor and miRNA Genes in Mouse Brain after Pentilenetetrazole-Induced Neuronal Activity.

Biochemistry. Biokhimii︠a︡
Anna A ShmakovaEkaterina V Semina
December 14, 2021
Open Access

The Role of Brain-Derived Neurotrophic Factor in Epileptogenesis: an Update.

Frontiers in Pharmacology
Xinyi WangKai Zhong
December 14, 2021

γ-Enolase enhances Trk endosomal trafficking and promotes neurite outgrowth in differentiated SH-SY5Y cells.

Cell Communication and Signaling : CCS
Anja Pišlar, Janko Kos
December 11, 2021

Functional characterization and potential therapeutic avenues for variants in the NTRK2 gene causing developmental and epileptic encephalopathies.

American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics
Ashlee LongDeeann Wallis

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