Next-Generation Therapeutics

Gene therapy and protein engineering strategies, guided by biological principles, are allowing ligands and receptors to be developed as next-generation therapeutics with improved safety and efficacy. Discover the latest research here.

January 5, 2021

Advanced liquid electrolytes enable practical applications of high-voltage lithium-metal full batteries

Chemical Communications : Chem Comm
Shulan MaoYingying Lu
December 18, 2020
Open Access

Tissue Engineered Bands of Büngner for Accelerated Motor and Sensory Axonal Outgrowth

Frontiers in Bioengineering and Biotechnology
Kate V PanzerD Kacy Cullen
December 5, 2020
Open Access

Next-generation cell therapies: the emerging role of CAR-NK cells

Rafet BasarKatayoun Rezvani
December 19, 2020
Open Access

EGFR-Binding Peptides: From Computational Design towards Tumor-Targeting of Adeno-Associated Virus Capsids

International Journal of Molecular Sciences
Rebecca C FeinerKristian M Müller
December 15, 2020
Open Access

Enhancing phage therapy through synthetic biology and genome engineering

Current Opinion in Biotechnology
Bryan R LennemanSamuel Kilcher
December 12, 2020

Uncovering a Culprit in CAR-T Resistance

Cancer Discovery
January 21, 2021

Anomalous Photoelectrical Properties through Strain Engineering Based on a Single Bent InAsSb Nanowire.

ACS Applied Materials & Interfaces
Xiaomei YaoJin Zou
December 9, 2020
Open Access

Turning Nature's own processes into design strategies for living bone implant biomanufacturing: a decade of Developmental Engineering.

Advanced Drug Delivery Reviews
Ioannis PapantoniouLiesbet Geris
January 22, 2021

Dual Site-Specific Chemoenzymatic Antibody Fragment Conjugation Using CRISPR-Based Hybridoma Engineering.

Bioconjugate Chemistry
C. M. Le GallMartijn Verdoes
December 16, 2020
Open Access

The default network of the human brain is associated with perceived social isolation

Nature Communications
R Nathan SprengDanilo Bzdok
December 8, 2020

CRISPR/Cas genome editing to optimize pharmacologically active plant natural products.

Pharmacological Research : the Official Journal of the Italian Pharmacological Society
Abhijit Dey
November 12, 2020
Open Access

The Immune Checkpoint PD-1 in Natural Killer Cells: Expression, Function and Targeting in Tumour Immunotherapy

Linda QuatriniLorenzo Moretta
December 31, 2020
Open Access

Genetic engineering of human and mouse CD4+ and CD8+ Tregs using lentiviral vectors encoding chimeric antigen receptors

Molecular Therapy. Methods & Clinical Development
Nadège VimondSéverine Bézie
December 8, 2020
Open Access

Dual site-specific chemoenzymatic antibody fragment conjugation using CRISPR-based hybridoma engineering

BioRxiv : the Preprint Server for Biology
C. M. Le GallMartijn Verdoes
December 15, 2020

Engaging endogenous opioid circuits in pain affective processes

Journal of Neuroscience Research
Blake A KimmeyGregory Corder

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