NFkB: Linking Inflammation and Cancer

Nuclear factor-κB (NFkB) signaling is an important pathway for regulating inflammation and is dysregulated in cancer. Chronic inflammation is involved in cancer development and progression. Discover the latest research here.

September 27, 2020

6-Methoxymellein Isolated from Carrot (Daucus carota L.) Targets Breast Cancer Stem Cells by Regulating NF-κB Signaling

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Ren LiuDong-Sun Lee
September 15, 2020
Open Access

Insight Into the Function of RIPK4 in Keratinocyte Differentiation and Carcinogenesis

Frontiers in Oncology
Jing XuZhixing He
September 19, 2020

The E2 ubiquitin-conjugating enzyme UbcH5c: an emerging target in cancer and immune disorders

Drug Discovery Today
Yuan ZhouJiang-Jiang Qin
September 15, 2020
Open Access

Ubiquitin-specific protease 7 downregulation suppresses breast cancer in vitro

Turkish Journal of Biology = Türk Biyoloji Dergisi
Taha Bartu HayalFikrettin Şahİn
September 28, 2020

Upregulation of HIF1-α via an NF-κB/COX2 pathway confers proliferative dominance of HER2-negative ductal carcinoma in situ cells in response to inflammatory stimuli

Neoplasia : an International Journal for Oncology Research
Dominika PiaseckaHanna M Romanska
September 16, 2020
Open Access

Development of a New and Improved Guanidine-based Rac1 Inhibitor with in Vivo Activity against Non-Small Cell Lung Cancer

Matias S CiarlantiniMaria Julieta Comin
September 26, 2020
Open Access

HSPA1L Enhances Cancer Stem Cell-Like Properties by Activating IGF1Rβ and Regulating β-Catenin Transcription

International Journal of Molecular Sciences
Soo-Im ChoiIn-Gyu Kim
September 15, 2020
Open Access

Icariin-induced inhibition of SIRT6/NF-κB triggers redox mediated apoptosis and enhances anti-tumor immunity in TNBC

Cancer Science
Linjiang SongXin Liang
September 23, 2020
Open Access

Targeting NF-κB pathway for the therapy of diseases: mechanism and clinical study

Signal Transduction and Targeted Therapy
Hui YuHongbo Hu

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