NK cell Signaling

Natural killer (NK) cells are cytotoxic cells of the innate immune system that respond to foreign or host cells displaying stress signals. NK cell activity is controlled by engagement of various cell surface receptors that induce activation or inhibitory pathways, the balance of which determines the cell’s phenotype. Find the latest research on NK cell signaling here.

April 17, 2021
Review

Role of immune regulatory cells in breast cancer: Foe or friend?

International Immunopharmacology
Huan-Rong LanXue Yang
April 16, 2021

Deconvoluting global cytokine signaling networks in natural killer cells.

Nature Immunology
Gabriela M WiedemannColleen M Lau
April 16, 2021

The transcriptional repressor ID2 supports natural killer cell maturation by controlling TCF1 amplitude.

The Journal of Experimental Medicine
Zhong-Yin LiBarbara L Kee
April 16, 2021
Open Access

Allogeneic Stem Cell Transplantation in Mature T Cell and Natural Killer/T Neoplasias: A Registry Study from Spanish GETH/GELTAMO Centers.

Transplantation and Cellular Therapy
Silvana NovelliGELTAMO and GETH
April 15, 2021

Astrocytes have a license to kill inflammatory T cells.

Immunity
Alice H K Kwon, Shane A Liddelow
April 15, 2021

Chronic stress physically spares but functionally impairs innate-like invariant T cells.

Cell Reports
Patrick T RudakS M Mansour Haeryfar
April 14, 2021
Open Access

Hypoxia enhances the production and antitumor effect of exosomes derived from natural killer cells.

Annals of Translational Medicine
Yanan JiangQiang Fu
April 14, 2021
Review
Open Access

Innate immune checkpoint inhibitors: the next breakthrough in medical oncology?

Molecular Cancer Therapeutics
Robert W LentzWells A Messersmith
April 14, 2021
Open Access

Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C.

Nature Communications
Shoeib MoradiJulian P Vivian
April 12, 2021
Preprint
Open Access

The PD-L1 and TLR7 dual-targeting nanobody-drug conjugate exerts potent antitumor efficacy by orchestrating innate and adaptive immune responses

BioRxiv : the Preprint Server for Biology
X. YuLikun Gong
April 12, 2021
Review
Open Access

The Role of Lytic Infection for Lymphomagenesis of Human γ-Herpesviruses.

Frontiers in Cellular and Infection Microbiology
Christian Münz
April 12, 2021
Open Access

Construction of in vitro patient-derived tumor models to evaluate anticancer agents and cancer immunotherapy.

Oncology Letters
Nobuhiko TakahashiMotoki Takagi
April 12, 2021
Review
Open Access

Advances in Understanding the Roles of CD244 (SLAMF4) in Immune Regulation and Associated Diseases.

Frontiers in Immunology
Lin SunGuixia Wang

Sign up to follow this feed and discover related papers.

Related Feeds

Antibodies: Agglutination

Antibody-mediated agglutination is the clumping of cells in the presence of antibody, which binds multiple cells together. This enhances the clearance of pathogens. Find the latest research on antibody-mediated agglutination here.

Antibodies: Complement Activation

The complement system can be activated by antigen-associated antibody. In the classical pathway of complement activation, C1q, C4b, and C3b are all able to bind to the Fc portion of IgG or IgM. Find the latest research on antibodies and complement activation here.

Antibody Development

Development of antibodies require integration of knowledge with respect to target antigen properties, antibody design criteria such as affinity, isotype selection, Fc domain engineering, and antibody cross-reactivity across species from the early stages of antibody development. Here is the latest research.


Antibody Specificity

Antibodies produced by B cells are highly specific for antigen as a result of random gene recombination and somatic hypermutation and affinity maturation. As the main effector of the humoral immune system, antibodies can neutralize foreign cells. Find the latest research on antibody specificity here.

Antibody synthesis

Antibodies have various functions including neutralization of pathogens, tumor targeting, as well as its utility in biomedical research. Here is the latest research on antibody synthesis.

Antibody-Dependent Cell Cytotoxicity

Antibody-dependent cellular toxicity refers to the lysis of a target cell by a non-sensitized effector cell of the immune system as a result of antibodies binding to the target cell membrane and engaging the Fc receptors on the immune effector cells. Find the latest research on antibody-dependent cellular toxicity here.

Antibody-Dependent Enhancement

Antibody-dependent enhancement of viral infection is the entry of virus into host cells mediated by antiviral antibodies interacting with Fc or complement receptors. This has been most extensively observed with the dengue virus. Find the latest research on antibody-dependent enhancement here.

Antigenic Modulation

Antigenic modulation occurs when an antibody cross-links antigens on a cell surface, causing the antigens to become internalized. This can lead to therapeutic failure of monoclonal antibodies as the expression of the antigen becomes decreased on target cells. Find the latest research on antigenic modulation here.

B cell Activation

B cell activation is initiated by the ligation of the B cell receptor with antigen and ultimately results in the production of protective antibodies against potentially pathogenic invaders. Here is the latest research.

B cell Differentiation

Depending on the signal received through the B cell receptor and other receptors, B cells differentiate into follicular or marginal zone B cells. Here is the latest research pertaining to this differentiation process.

© 2021 Meta ULC. All rights reserved
/feed-previews/nk-cell-signaling/257f1e46-fcc8-4587-9467-797a208a9b47