NK cell Signaling

Natural killer (NK) cells are cytotoxic cells of the innate immune system that respond to foreign or host cells displaying stress signals. NK cell activity is controlled by engagement of various cell surface receptors that induce activation or inhibitory pathways, the balance of which determines the cell’s phenotype. Find the latest research on NK cell signaling here.

April 17, 2021

Role of immune regulatory cells in breast cancer: Foe or friend?

International Immunopharmacology
Huan-Rong LanXue Yang
April 16, 2021

Deconvoluting global cytokine signaling networks in natural killer cells.

Nature Immunology
Gabriela M WiedemannColleen M Lau
April 16, 2021

The transcriptional repressor ID2 supports natural killer cell maturation by controlling TCF1 amplitude.

The Journal of Experimental Medicine
Zhong-Yin LiBarbara L Kee
April 16, 2021
Open Access

Allogeneic Stem Cell Transplantation in Mature T Cell and Natural Killer/T Neoplasias: A Registry Study from Spanish GETH/GELTAMO Centers.

Transplantation and Cellular Therapy
Silvana NovelliGELTAMO and GETH
April 15, 2021

Astrocytes have a license to kill inflammatory T cells.

Alice H K Kwon, Shane A Liddelow
April 15, 2021

Chronic stress physically spares but functionally impairs innate-like invariant T cells.

Cell Reports
Patrick T RudakS M Mansour Haeryfar
April 14, 2021
Open Access

Hypoxia enhances the production and antitumor effect of exosomes derived from natural killer cells.

Annals of Translational Medicine
Yanan JiangQiang Fu
April 14, 2021
Open Access

Innate immune checkpoint inhibitors: the next breakthrough in medical oncology?

Molecular Cancer Therapeutics
Robert W LentzWells A Messersmith
April 14, 2021
Open Access

Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C.

Nature Communications
Shoeib MoradiJulian P Vivian
April 12, 2021
Open Access

The PD-L1 and TLR7 dual-targeting nanobody-drug conjugate exerts potent antitumor efficacy by orchestrating innate and adaptive immune responses

BioRxiv : the Preprint Server for Biology
X. YuLikun Gong
April 12, 2021
Open Access

The Role of Lytic Infection for Lymphomagenesis of Human γ-Herpesviruses.

Frontiers in Cellular and Infection Microbiology
Christian Münz
April 12, 2021
Open Access

Construction of in vitro patient-derived tumor models to evaluate anticancer agents and cancer immunotherapy.

Oncology Letters
Nobuhiko TakahashiMotoki Takagi
April 12, 2021
Open Access

Advances in Understanding the Roles of CD244 (SLAMF4) in Immune Regulation and Associated Diseases.

Frontiers in Immunology
Lin SunGuixia Wang

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