NK cells identify and attack target cells based on integration of signals from activation and inhibitory receptors, whose ligands exhibit complex expression and/or binding patterns. Here is the latest research.
The Alternative Complement Pathway is part of the innate immune system, and activation generates membrane attack complexes that kill pathogenic cells. Discover the latest research on the Alternative Complement Pathway.
Adjuvants systems that are added to vaccines against avian influenza have be explored to enhance the innate immune system response against the virus. Here is the latest research on avian influenza and the innate immune adjuvant.
Basophils are myeloid cells with a high affinity IgE receptor and is involved in inflammatory responses during allergy. Discover the latest research on Basophils here.
The Classical Complement Pathway is activated by antigen-antibody complexes. Activation of this pathway leads to the generation of the membrane attack complex, which kills pathogenic cells. Discover the latest research on the Classical Complement Pathway here.
The Mannose-Binding Lectin Complement Pathway is activated when mannose-binding lectin binds to mannose found on the surface of pathogens. Subsequent complement activation is similar to the classical complement pathway, but without the need for antigen-antibody complexes. Discover the latest research here.
Inflammation Mediators include cytokines, prostaglandins and other molecules that ochestrate the inflammatory process in response to injury, allergy or pathogens. Discover the latest research on Inflammation Mediators here.
Innate immune responses in the CNS are carried out by microglia and astrocytes. Here is the latest research on mechanisms underlying innate immunity in the CNS and its impact on neurophysiology.
Many components of the mammalian innate immune system have homologs in lower organisms, such as invertebrates. Discover the latest research on Innate Immunity in Lower Organisms here.
The innate immune system is a first line of defense against infection. Pathological states can occur if there is over activation of the innate immune system, particularly in the. The excessive activation of these cells can lead to inflammation and neurodegenerative diseases. Here is the latest research on innate immunity and neurodegeneration.
Intracellular killing involves the death of microbes within the phagocyte. Here is the latest research on intracellular killing.