NMDA antagonists: Antidepressant properties

Despite widely reported clinical and preclinical studies of rapid antidepressant actions of NMDA receptor antagonists, there has been very little work examining the effects of these drugs in stress models of depression that require chronic administration of antidepressants or the molecular mechanisms that could account for the rapid responses. Discover the latest research here.

July 28, 2020
Open Access

Sustained Improvement of Negative Self-Schema After a Single Ketamine Infusion: An Open-Label Study

Frontiers in Neuroscience
Gregor HaslerYoan Mihov
July 14, 2020
Open Access

The Effect of Ketamine on Electrophysiological Connectivity in Major Depressive Disorder

Frontiers in Psychiatry
Allison C NugentCarlos A Zarate
July 10, 2020
Open Access

Ketamine and Ro 25-6981 Reverse Behavioral Abnormalities in Rats Subjected to Dietary Zinc Restriction

International Journal of Molecular Sciences
Bartłomiej PochwatGabriel Nowak
July 14, 2020

A preliminary study of adjunctive ketamine for treatment-resistant bipolar depression

Journal of Affective Disorders
Wei ZhengYu-Ping Ning
July 4, 2020

Antidepressant mechanisms of ketamine: Focus on GABAergic inhibition

Advances in Pharmacology
Bernhard LuscherSarah J Jefferson
July 4, 2020

Neurobiological biomarkers of response to ketamine

Advances in Pharmacology
Bashkim KadriuCarlos A Zarate
July 11, 2020
Open Access

Pharmacological treatment of neuropsychiatric symptoms of dementia: a network meta-analysis protocol

Annals of Translational Medicine
Yu-Yuan HuangJin-Tai Yu
August 11, 2020
Open Access

Ayahuasca - potential therapeutic properties in psychiatry. Research review

Psychiatria polska
Aleksandra Barabasz-Gembczyk, Krzysztof Kucia
July 2, 2020
Open Access

Pharmacological Treatment of Bipolar Depression: What are the Current and Emerging Options?

Neuropsychiatric Disease and Treatment
Nefize Yalin, Allan H Young
July 25, 2020

Multiple cellular targets involved in the antidepressant-like effect of glutathione

Chemico-biological Interactions
Alcir Luiz DafreMauricio Peña Cunha
July 23, 2020

Antidepressant effects of ketamine and ECT: A pilot comparison

Journal of Affective Disorders
Ravi K SharmaJagadisha Thirthalli
July 4, 2020

mGlu2/3 receptor as a novel target for rapid acting antidepressants

Advances in Pharmacology
Shigeyuki Chaki
August 7, 2020

Assessment of the rapid and sustained antidepressant-like effects of dextromethorphan in mice

Pharmacology, Biochemistry, and Behavior
Jesus S SaavedraTodd M Hillhouse

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