Feed Preview

Fast Growing

Non-coding Variants in Cancer

Non-coding Variants in Cancer diagram by Ppgardne ; ilusmedical, Wikimedia
Ppgardne ; ilusmedical, Wikimedia

Mutations, single nucleotide variants and large genomic rearrangements, in non-coding regions of the genome can have severe consequences such as disruption of transcription factor binding sites and functions of non-coding RNAs and can impact tumor development and progression. Here is the latest research.

Top 20 most recent papers
Genome Biology

Gene content evolution in the arthropods

Genome BiologyJanuary 24, 2020
Gregg W C ThomasStephen Richards
247
4
1
Nucleic Acids Research

Dynamic changes in cis-regulatory occupancy by Six1 and its cooperative interactions with distinct cofactors drive lineage-specific gene expression programs during progressive differentiation of the auditory sensory epithelium

Nucleic Acids ResearchJanuary 21, 2020
Jun LiPin-Xian Xu
2
Nucleic Acids Research

Haplotyping by CRISPR-mediated DNA circularization (CRISPR-hapC) broadens allele-specific gene editing

Nucleic Acids ResearchJanuary 17, 2020
Jiaying YuLin Lin
4
Nucleic Acids Research

The human ZC3H3 and RBM26/27 proteins are critical for PAXT-mediated nuclear RNA decay

Nucleic Acids ResearchJanuary 18, 2020
Toomas SillaTorben Heick Jensen
EBioMedicine

Corrigendum to 'Exosomal miRNA confers chemo resistance via targeting Cav1/p-gp/M2-type macrophage axis in ovarian cancer' [EBioMedicine 38 (2018) 100-112

EBioMedicineJanuary 24, 2020
Pinar KanlikilicerGabriel Lopez-Berestein
Nucleic Acids Research

HSF2BP negatively regulates homologous recombination in DNA interstrand crosslink repair

Nucleic Acids ResearchJanuary 22, 2020
Koichi SatoAlex N Zelensky
4
1
Nucleic Acids Research

A crucial RNA-binding lysine residue in the Nab3 RRM domain undergoes SET1 and SET3-responsive methylation

Nucleic Acids ResearchJanuary 22, 2020
Kwan Yin LeeMarc D Meneghini
Nucleic Acids Research

SIRT6 coordinates with CHD4 to promote chromatin relaxation and DNA repair

Nucleic Acids ResearchJanuary 24, 2020
Tianyun HouWei-Guo Zhu
1
Genome Biology

Enteric infection induces Lark-mediated intron retention at the 5' end of Drosophila genes

Genome BiologyJanuary 18, 2020
Maroun Bou SleimanBart Deplancke
26
3
Cancers

The Long Non-Coding RNA Prader Willi/Angelman Region RNA5 (PAR5 ) Is Downregulated in Anaplastic Thyroid Carcinomas Where It Acts as a Tumor Suppressor by Reducing EZH2 Activity

CancersJanuary 23, 2020
Simona PellecchiaPierlorenzo Pallante
Genome Biology

cis-regulatory variation modulates susceptibility to enteric infection in the Drosophila genetic reference panel

Genome BiologyJanuary 18, 2020
Michael V FrochauxBart Deplancke
21
3
Nucleic Acids Research

Prevalence and architecture of posttranscriptionally impaired synonymous mutations in 8,320 genomes across 22 cancer types

Nucleic Acids ResearchJanuary 18, 2020
Huajing TengZhongsheng Sun
4
1
Nucleic Acids Research

Stress-induced lncRNA LASTR fosters cancer cell fitness by regulating the activity of the U4/U6 recycling factor SART3

Nucleic Acids ResearchJanuary 21, 2020
Linde De TroyerAnna A Sablina
8
Nucleic Acids Research

DNA targeting by Clostridium cellulolyticum CRISPR-Cas9 Type II-C system

Nucleic Acids ResearchJanuary 17, 2020
Iana FedorovaKonstantin Severinov
3
Genome Biology

A curated benchmark of enhancer-gene interactions for evaluating enhancer-target gene prediction methods

Genome BiologyJanuary 24, 2020
Jill E MooreZhiping Weng
24
Genome Biology

Performance difference of graph-based and alignment-based hybrid error correction methods for error-prone long reads

Genome BiologyJanuary 19, 2020
Anqi Wang, Kin Fai Au
34
Nucleic Acids Research

Modulated control of DNA supercoiling balance by the DNA-wrapping domain of bacterial gyrase

Nucleic Acids ResearchJanuary 18, 2020
Matthew J HobsonJames M Berger
2
Journal of Cellular Physiology

Rs11655237 polymorphism of LINC00673 affects the prognosis of cervical cancer by interfering with the interaction between LINC00673 and microRNA-1231

Journal of Cellular PhysiologyJanuary 21, 2020
Wei ZhuDejia Li
Nucleic Acids Research

The SERRATE protein is involved in alternative splicing in Arabidopsis thaliana

Nucleic Acids ResearchJanuary 21, 2020
Katarzyna Dorota RaczynskaArtur Jarmolowski
Nucleic Acids Research

Dynamics of the nucleosomal histone H3 N-terminal tail revealed by high precision single-molecule FRET

Nucleic Acids ResearchJanuary 21, 2020
Kathrin LehmannJörg Langowski
9

See more papers from this feed

Related Feeds

AAV-based Gene Therapy

Adeno-associated virus (AAV)-based gene therapy is a biological vector that is being researched to be used as a potential therapeutic option. This gene therapy is designed to insert fragments of DNA into targeted cells to help treat diseases, such as hemophilia a. Discover the latest research on AAV-based gene therapy here.

ALS: Genetics

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. ALS is a genetically heterogeneous disorder with several causative genes. Here are the latest discoveries pertaining to the genetics of this disease.

Acute Myeloid Leukaemia & RNA

Acute myeloid leukaemia (AML) is a common hematological type of cancer. As the population ages, there has been a rise in the frequency of AML. RNA expression has been used to see if there are different genetic profiles that exist within AML and whether these may underpin the variations in survival rates. Here is the latest research on AML and RNA.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.

Alzheimer's Disease: Genetics

Alzheimer's disease is a chronic neurodegenerative disease. Discover genetic and epigenetic aspects of Alzheimer’s disease, including genetic markers and genomic structural variations here.

Alzheimer's Disease: RNA Sequencing

RNA sequencing is used to reveal the presence and quantity of RNA in a given sample. In this feed, RNA sequencing investigates the genetic and molecular mechanisms related to the pathophysiology of Alzheimer's disease (AD). Here are the latest discoveries pertaining to RNA sequencing and this disease.

Antisense Oligonucleotides: ND

This feed focuses on antisense oligonucleotide therapies such as Inotersen, Nusinursen, and Patisiran, in neurodegenerative diseases including amyotrophic lateral sclerosis.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Breast Cancer: Risk Factors

Breast cancer is a multifactorial disease that is influenced by both environmental and genetic factors. Discover the latest research on the environmental and genetic risk factors for breast cancer here.

© 2020 Meta ULC. All rights reserved
/feed-previews/non-coding-variants-in-cancer/21a1e743-ffa9-42d4-a082-fb853d2acccd