Feed Preview

Fast Growing

Non-coding Variants in Cancer

Non-coding Variants in Cancer diagram by undefined

Mutations, single nucleotide variants and large genomic rearrangements, in non-coding regions of the genome can have severe consequences such as disruption of transcription factor binding sites and functions of non-coding RNAs and can impact tumor development and progression. Here is the latest research.

Top 20 most recent papers
Genome Biology

Dashing: fast and accurate genomic distances with HyperLogLog

Genome BiologyDecember 4, 2019
Daniel N Baker, Ben Regina Langmead
Genome Biology

Common DNA sequence variation influences 3-dimensional conformation of the human genome

Genome BiologyNovember 28, 2019
David U. GorkinBing Ren
Nucleic Acids Research

Structural basis of non-canonical transcriptional regulation by the σA-bound iron-sulfur protein WhiB1 in M. tuberculosis

Nucleic Acids ResearchDecember 6, 2019
Tao WanLi-Mei Zhang
Nucleic Acids Research

FLASH: ultra-fast protocol to identify RNA-protein interactions in cells

Nucleic Acids ResearchDecember 5, 2019
Ibrahim Avsar IlikAsifa Akhtar
Nucleic Acids Research

Hybridization-mediated off-target effects of splice-switching antisense oligonucleotides

Nucleic Acids ResearchDecember 5, 2019
Juergen ScharnerAdrian R. Krainer
Genome Biology

Afann: bias adjustment for alignment-free sequence comparison based on sequencing data using neural network regression

Genome BiologyDecember 4, 2019
Kujin TangFengzhu Sun
Nucleic Acids Research

AtFKBP53: a chimeric histone chaperone with functional nucleoplasmin and PPIase domains

Nucleic Acids ResearchDecember 6, 2019
Ajit Kumar SinghDileep Vasudevan
Genome Biology

Pharmacogenomic analysis of patient-derived tumor cells in gynecologic cancers

Genome BiologyNovember 26, 2019
Jason Kyungha SaJeong-Won Lee
Nucleic Acids Research

Same fold, different properties: polarizable molecular dynamics simulations of telomeric and TERRA G-quadruplexes

Nucleic Acids ResearchDecember 6, 2019
Justin A Lemkul
Genome Biology

Improved metagenomic analysis with Kraken 2

Genome BiologyNovember 28, 2019
Derrick E WoodBen Regina Langmead
Genome Biology

RegSNPs-intron: a computational framework for predicting pathogenic impact of intronic single nucleotide variants

Genome BiologyNovember 28, 2019
Hai LinYun-Long Liu
Nucleic Acids Research

The human HELLS chromatin remodelling protein promotes end resection to facilitate homologous recombination and contributes to DSB repair within heterochromatin

Nucleic Acids ResearchDecember 5, 2019
Gabriel KollarovicAnna Louise Chambers
Nucleic Acids Research

mRNA regions where 80S ribosomes pause during translation elongation in vivo interact with protein uS19, a component of the decoding site

Nucleic Acids ResearchDecember 5, 2019
Elena S BabaylovaGalina G Karpova
Nucleic Acids Research

Phosphorylation of Tet3 by cdk5 is critical for robust activation of BRN2 during neuronal differentiation

Nucleic Acids ResearchDecember 6, 2019
Vinay Kumar RaoChin-Tong Ong
Nucleic Acids Research

Cross-subunit catalysis and a new phenomenon of recessive resurrection in Escherichia coli RNase E

Nucleic Acids ResearchDecember 5, 2019
Nida Ali, Jayaraman Gowrishankar
Nucleic Acids Research

Expanding the editable genome and CRISPR-Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nicking

Nucleic Acids ResearchDecember 4, 2019
Xiao-Yu ChenManuel A F V Gonçalves
Genome Biology

methylCC: technology-independent estimation of cell type composition using differentially methylated regions

Genome BiologyNovember 29, 2019
Stephanie C. Hicks, Rafael A. Irizarry
OncoTargets and Therapy

Identification Of Actionable Genetic Targets In Primary Cardiac Sarcomas

OncoTargets and TherapyNovember 7, 2019
Carmen Salvador-ColomaJaime Font de Mora
International Journal of Molecular Sciences

ABCC3 Expressed by CD56dim CD16+ NK Cells Predicts Response in Glioblastoma Patients Treated with Combined Chemotherapy and Dendritic Cell Immunotherapy

International Journal of Molecular SciencesNovember 23, 2019
Serena PellegattaGaetano Finocchiaro

Correlation between FAS single nucleotide polymorphisms and breast carcinoma susceptibility in Asia

MedicineDecember 1, 2019
Ying ChenBen-zhong Wang

See more papers from this feed

Related Feeds

AAV-based Gene Therapy

Adeno-associated virus (AAV)-based gene therapy is a biological vector that is being researched to be used as a potential therapeutic option. This gene therapy is designed to insert fragments of DNA into targeted cells to help treat diseases, such as hemophilia a. Discover the latest research on AAV-based gene therapy here.

ALS: Genetics

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. ALS is a genetically heterogeneous disorder with several causative genes. Here are the latest discoveries pertaining to the genetics of this disease.

Acute Myeloid Leukaemia & RNA

Acute myeloid leukaemia (AML) is a common hematological type of cancer. As the population ages, there has been a rise in the frequency of AML. RNA expression has been used to see if there are different genetic profiles that exist within AML and whether these may underpin the variations in survival rates. Here is the latest research on AML and RNA.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.

Alzheimer's Disease: Genetics

Alzheimer's disease is a chronic neurodegenerative disease. Discover genetic and epigenetic aspects of Alzheimer’s disease, including genetic markers and genomic structural variations here.

Alzheimer's Disease: RNA Sequencing

RNA sequencing is used to reveal the presence and quantity of RNA in a given sample. In this feed, RNA sequencing investigates the genetic and molecular mechanisms related to the pathophysiology of Alzheimer's disease (AD). Here are the latest discoveries pertaining to RNA sequencing and this disease.

Antisense Oligonucleotides: ND

This feed focuses on antisense oligonucleotide therapies such as Inotersen, Nusinursen, and Patisiran, in neurodegenerative diseases including amyotrophic lateral sclerosis.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Breast Cancer: Risk Factors

Breast cancer is a multifactorial disease that is influenced by both environmental and genetic factors. Discover the latest research on the environmental and genetic risk factors for breast cancer here.

© 2019 Meta ULC. All rights reserved