Non-coding Variants in Cancer

Mutations, single nucleotide variants and large genomic rearrangements, in non-coding regions of the genome can have severe consequences such as disruption of transcription factor binding sites and functions of non-coding RNAs and can impact tumor development and progression. Here is the latest research.

September 16, 2020
Open Access

Merqury: reference-free quality, completeness, and phasing assessment for genome assemblies

Genome Biology
Arang RhieAdam M Phillippy
September 12, 2020
Open Access

STARR-seq identifies active, chromatin-masked, and dormant enhancers in pluripotent mouse embryonic stem cells

Genome Biology
Tianran PengWout Megchelenbrink
September 8, 2020
Open Access

The Tug1 lncRNA locus is essential for male fertility

Genome Biology
Jordan P LewandowskiJohn L Rinn
September 8, 2020
Open Access

COCOA: coordinate covariation analysis of epigenetic heterogeneity

Genome Biology
John T LawsonNathan C Sheffield
September 16, 2020

CYP27B1 rs10877012 T allele was linked to non-AIDS progression in ART-naïve HIV-infected patients: a retrospective study

Journal of Acquired Immune Deficiency Syndromes : JAIDS
María A Jiménez-SousaSalvador Resino
September 6, 2020
Open Access

On the expanding roles of tRNA fragments in modulating cell behavior

Nucleic Acids Research
Rogan Magee, Isidore Rigoutsos
September 8, 2020
Open Access

Histone chaperone FACT represses retrotransposon MERVL and MERVL-derived cryptic promoters

Nucleic Acids Research
Fuquan ChenXinyi Lu
September 8, 2020
Open Access

Comprehensive classification of ABC ATPases and their functional radiation in nucleoprotein dynamics and biological conflict systems

Nucleic Acids Research
Arunkumar KrishnanL Aravind
September 6, 2020
Open Access

Clinical PARP inhibitors do not abrogate PARP1 exchange at DNA damage sites in vivo

Nucleic Acids Research
Zhengping ShaoShan Zha
September 8, 2020
Open Access

Alignment and mapping methodology influence transcript abundance estimation

Genome Biology
Avi SrivastavaRob Patro
September 12, 2020
Open Access

Impact of admixture and ancestry on eQTL analysis and GWAS colocalization in GTEx

Genome Biology
Nicole R GayStephen B Montgomery
September 6, 2020
Open Access

SPOC1 modulates DNA repair by regulating key determinants of chromatin compaction and DNA damage response

Nucleic Acids Research
Andreas MundHans Will
September 11, 2020
Open Access

Natural display of nuclear-encoded RNA on the cell surface and its impact on cell interaction

Genome Biology
Norman HuangSheng Zhong
September 12, 2020
Open Access

GetOrganelle: a fast and versatile toolkit for accurate de novo assembly of organelle genomes

Genome Biology
Jian-Jun JinDe-Zhu Li
September 12, 2020
Open Access

Metalign: efficient alignment-based metagenomic profiling via containment min hash

Genome Biology
Nathan LaPierreSerghei Mangul
September 8, 2020
Open Access

The wild grape genome sequence provides insights into the transition from dioecy to hermaphroditism during grape domestication

Genome Biology
Hélène BadouinGabriel A B Marais
September 6, 2020
Review

Polymorphism of lncRNAs in breast cancer: Meta-analysis shows no association with susceptibility

The Journal of Gene Medicine
Carolina MathiasJaqueline Carvalho de Oliveira
September 6, 2020
Open Access

Rapid, robust plasmid verification by de novo assembly of short sequencing reads

Nucleic Acids Research
Jenna E GallegosJean Peccoud

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