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Non-coding Variants in Cancer
Ppgardne ; ilusmedical, WikimediaMutations, single nucleotide variants and large genomic rearrangements, in non-coding regions of the genome can have severe consequences such as disruption of transcription factor binding sites and functions of non-coding RNAs and can impact tumor development and progression. Here is the latest research.
Top 20 most recent papers
Gene content evolution in the arthropods
Genome BiologyJanuary 24, 2020
Gregg W C ThomasStephen Richards
247
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1
Dynamic changes in cis-regulatory occupancy by Six1 and its cooperative interactions with distinct cofactors drive lineage-specific gene expression programs during progressive differentiation of the auditory sensory epithelium
Nucleic Acids ResearchJanuary 21, 2020
Jun LiPin-Xian Xu
2
Haplotyping by CRISPR-mediated DNA circularization (CRISPR-hapC) broadens allele-specific gene editing
Nucleic Acids ResearchJanuary 17, 2020
Jiaying YuLin Lin
4
The human ZC3H3 and RBM26/27 proteins are critical for PAXT-mediated nuclear RNA decay
Nucleic Acids ResearchJanuary 18, 2020
Toomas SillaTorben Heick Jensen
Corrigendum to 'Exosomal miRNA confers chemo resistance via targeting Cav1/p-gp/M2-type macrophage axis in ovarian cancer' [EBioMedicine 38 (2018) 100-112
EBioMedicineJanuary 24, 2020
Pinar KanlikilicerGabriel Lopez-Berestein
HSF2BP negatively regulates homologous recombination in DNA interstrand crosslink repair
Nucleic Acids ResearchJanuary 22, 2020
Koichi SatoAlex N Zelensky
4
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A crucial RNA-binding lysine residue in the Nab3 RRM domain undergoes SET1 and SET3-responsive methylation
Nucleic Acids ResearchJanuary 22, 2020
Kwan Yin LeeMarc D Meneghini
SIRT6 coordinates with CHD4 to promote chromatin relaxation and DNA repair
Nucleic Acids ResearchJanuary 24, 2020
Tianyun HouWei-Guo Zhu
1
Enteric infection induces Lark-mediated intron retention at the 5' end of Drosophila genes
Genome BiologyJanuary 18, 2020
Maroun Bou SleimanBart Deplancke
26
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The Long Non-Coding RNA Prader Willi/Angelman Region RNA5 (PAR5 ) Is Downregulated in Anaplastic Thyroid Carcinomas Where It Acts as a Tumor Suppressor by Reducing EZH2 Activity
CancersJanuary 23, 2020
Simona PellecchiaPierlorenzo Pallante
cis-regulatory variation modulates susceptibility to enteric infection in the Drosophila genetic reference panel
Genome BiologyJanuary 18, 2020
Michael V FrochauxBart Deplancke
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Prevalence and architecture of posttranscriptionally impaired synonymous mutations in 8,320 genomes across 22 cancer types
Nucleic Acids ResearchJanuary 18, 2020
Huajing TengZhongsheng Sun
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Stress-induced lncRNA LASTR fosters cancer cell fitness by regulating the activity of the U4/U6 recycling factor SART3
Nucleic Acids ResearchJanuary 21, 2020
Linde De TroyerAnna A Sablina
8
DNA targeting by Clostridium cellulolyticum CRISPR-Cas9 Type II-C system
Nucleic Acids ResearchJanuary 17, 2020
Iana FedorovaKonstantin Severinov
3
A curated benchmark of enhancer-gene interactions for evaluating enhancer-target gene prediction methods
Genome BiologyJanuary 24, 2020
Jill E MooreZhiping Weng
24
Performance difference of graph-based and alignment-based hybrid error correction methods for error-prone long reads
Genome BiologyJanuary 19, 2020
Anqi Wang, Kin Fai Au
34
Modulated control of DNA supercoiling balance by the DNA-wrapping domain of bacterial gyrase
Nucleic Acids ResearchJanuary 18, 2020
Matthew J HobsonJames M Berger
2
Rs11655237 polymorphism of LINC00673 affects the prognosis of cervical cancer by interfering with the interaction between LINC00673 and microRNA-1231
Journal of Cellular PhysiologyJanuary 21, 2020
Wei ZhuDejia Li
The SERRATE protein is involved in alternative splicing in Arabidopsis thaliana
Nucleic Acids ResearchJanuary 21, 2020
Katarzyna Dorota RaczynskaArtur Jarmolowski
Dynamics of the nucleosomal histone H3 N-terminal tail revealed by high precision single-molecule FRET
Nucleic Acids ResearchJanuary 21, 2020
Kathrin LehmannJörg Langowski
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