Nutrient-sensing Pathways & Aging

Nutrient sensing pathways such as insulin-like growth factor and TOR signaling are being explored for their involvement in aging. Healthy dietary modifications have been shown to slow the progression of aging. Discover the latest research on nutrient-sensing pathways and aging here.

June 25, 2020

L-type amino acid transporter 1, LAT1, in growth hormone-producing pituitary tumor cells

Molecular and Cellular Endocrinology
Motoyasu SatouToru Tateno
June 17, 2020
Open Access

Iron chelation inhibits mTORC1 signaling involving activation of AMPK and REDD1/Bnip3 pathways

Oncogene
Chaowei ShangShile Huang
July 8, 2020

Nutrient Control of mRNA Translation

Annual Review of Nutrition
Xin Erica ShuShu-Bing Qian
June 27, 2020
Open Access

Global alterations to the choroid plexus blood-CSF barrier in amyotrophic lateral sclerosis

Acta Neuropathologica Communications
J SaulN Bakkar
June 17, 2020

Expression and functional analysis of the Akt gene from Daphnia pulex

Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology
Xuanyu ZhouYunlong Zhao
June 20, 2020
Review

New and Emerging Targeted Therapies for Vascular Malformations

American Journal of Clinical Dermatology
An Van DammeMiikka Vikkula
June 5, 2020

Crocin Reverses Depression-Like Behavior in Parkinson Disease Mice via VTA-mPFC Pathway

Molecular Neurobiology
Juanjuan TangGang Chen
July 9, 2020
Review

Metabolic pathways in context: mTOR signalling in the retina and optic nerve

Clinical & Experimental Ophthalmology
Anthony Yao, Peter van Wijngaarden
July 11, 2020
Review

Exaptive Evolution of Target of Rapamycin Signaling in Multicellular Eukaryotes

Developmental Cell
Jacob O Brunkard
July 7, 2020

ELT-2 promotes O-GlcNAc transferase OGT-1 expression to modulate Caenorhabditis elegans lifespan

Journal of Cellular Biochemistry
Liangping SuXiaoxue Li
June 21, 2020
Open Access

The role of myeloid-derived suppressor cells in increasing cancer stem-like cells and promoting PD-L1 expression in epithelial ovarian cancer

Cancer Immunology, Immunotherapy : CII
Naoko KomuraTadashi Kimura
July 3, 2020
Open Access

Antimycobacterial Effects of Everolimus in a Human Granuloma Model

Journal of Clinical Medicine
David AshleyVishwanath Venketaraman
July 8, 2020
Review
Open Access

The PI3K-AKT-mTOR Pathway and Prostate Cancer: At the Crossroads of AR, MAPK, and WNT Signaling

International Journal of Molecular Sciences
Boris Y ShorningHelen B Pearson
June 18, 2020
Review
Open Access

Nutrition and Sarcopenia-What Do We Know?

Nutrients
Aravinda Ganapathy, Jeri W Nieves
July 1, 2020
Open Access

Increase in blood-brain barrier leakage in healthy, older adults

GeroScience
Inge C M VerheggenWalter H Backes

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