Organization of DNA Replication

DNA replication requires a concerted effort of numerous proteins and replication units to organize the densely packed DNA within the nucleus and is a highly regulated process. Discover the latest research on Organization of DNA Replication here.

January 15, 2021
Open Access

Hydrogen-deuterium exchange reveals a dynamic DNA-binding map of replication protein A

Nucleic Acids Research
Faiz AhmadEdwin Antony
January 22, 2021

Mechanism of Deoxyguanosine Diphosphate Insertion by Human DNA Polymerase β.

Fausto A Varela, Bret D Freudenthal
January 17, 2021

Alternative lengthening of telomeres is a self-perpetuating process in ALT-associated PML bodies

Molecular Cell
Jia-Min ZhangLee Zou
January 22, 2021
Open Access

DDX1 from Cherry valley duck mediates signaling pathways and anti-NDRV activity.

Veterinary Research
Huihui ZhangLiangmeng Wei
January 24, 2021

Single-strand DNA breaks cause replisome disassembly.

Molecular Cell
Kyle B VrtisJohannes C Walter
January 19, 2021
Open Access

Ongoing replication forks delay the nuclear envelope breakdown upon mitotic entry.

The Journal of Biological Chemistry
Yoshitami Hashimoto, Hirofumi Tanaka
January 18, 2021
Open Access

Determinants of replication protein A subunit interactions revealed using a phosphomimetic peptide

The Journal of Biological Chemistry
Sungjin LeeChin-Ju Park
January 14, 2021
Open Access

Structural basis for the multi-activity factor Rad5 in replication stress tolerance.

Nature Communications
Miaomiao ShenSong Xiang
January 12, 2021

Checkpoint functions of RecQ helicases at perturbed DNA replication fork

Current Genetics
Nafees AhamadYong-Jie Xu
January 13, 2021

Genome copy number regulates inclusion expansion, septation, and infectious developmental form conversion in Chlamydia trachomatis

Journal of Bacteriology
Julie A BrothwellGeorge W Liechti
January 25, 2021
Open Access

Molecular and structural characterization of oxidized ribonucleotide insertion into DNA by human DNA polymerase β.

The Journal of Biological Chemistry
Mallory R SmithBret D Freudenthal
January 17, 2021

RADX controls RAD51 filament dynamics to regulate replication fork stability

Molecular Cell
Madison B AdolphDavid Cortez
January 13, 2021
Open Access

HERC2 inactivation abrogates nucleolar localization of RecQ helicases BLM and WRN

Scientific Reports
Mingzhang ZhuTomohiko Ohta
January 22, 2021
Open Access

High-fidelity DNA ligation enforces accurate Okazaki fragment maturation during DNA replication.

Nature Communications
Jessica S WilliamsThomas A Kunkel

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