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Organoids in Cancer Research

Organoids in Cancer Research diagram by Wang et al, PLOS One
Wang et al, PLOS One

Organoids are 3D organ-like structures that can be derived from patient tumor cells to model disease. Discover the latest research here.

Top 20 most recent papers

Basal-like and Classical cells coexistence in pancreatic cancer revealed by single cell analysis

bioRxivJanuary 8, 2020
Nelson J. DusettiJuan L Iovanna

A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity

CellDecember 31, 2019
Fadi JacobHongjun Song
The Keio Journal of Medicine

Organoids: Avatars for Personalized Medicine

The Keio Journal of MedicineDecember 26, 2019
Hans Clevers

Regulation of HDAC2-PDX1 by RNF125 defines pancreatic cancer development

bioRxivJanuary 7, 2020
Eerz HasnisZe'ev A Ronai

A Multi-Niche Microvascularized Human Bone-Marrow-on-a-Chip

bioRxivDecember 24, 2019
Michael R. NelsonKrishnendu Roy

The novel reversible LSD1 inhibitor SP-2577 promotes anti-tumor immunity in SWItch/Sucrose-NonFermentable (SWI/SNF) complex mutated ovarian cancer

bioRxivJanuary 11, 2020
Raffaella SoldiSunil Sharma
Cell Stem Cell

Organoids as Oracles for Precision Medicine in Rectal Cancer

Cell Stem CellJanuary 18, 2020
Kevin S KolahiCalvin J Kuo

LKB1 Represses ATOH1 via PDK4 and Energy Metabolism and Regulates Intestinal Stem Cell Fate

GastroenterologyJanuary 14, 2020
Yajing GaoTomi P Mäkelä

Modulation of the canonical Wnt activity by androgen signaling in prostate epithelial basal stem cells

bioRxivJanuary 11, 2020
Yueli LiuZhu A. Wang
Nature Communications

Gastric squamous-columnar junction contains a large pool of cancer-prone immature osteopontin responsive Lgr5- CD44+ cells

Nature CommunicationsJanuary 5, 2020
Dah-Jiun FuAlexander Yu. Nikitin

WNT and inflammatory signaling distinguish human Fallopian tube epithelial cell populations

bioRxivJanuary 16, 2020
Ian M. RoseAlexander Yu. Nikitin

Longitudinal cancer evolution from single cells

bioRxivJanuary 15, 2020
Daniele RamazzottiAlex Graudenzi

Repurposing Antibacterial AM404 as a Potential Anticancer Drug for Targeting Colorectal Cancer Stem-Like Cells

CancersJanuary 8, 2020
Mehreen AhmedAbdolrahman S Nateri
International Journal of Clinical and Experimental Pathology

Large cell neuroendocrine carcinoma arising from uterine endometrium with rapidly progressive course: report of a case and review of literature

International Journal of Clinical and Experimental PathologyJanuary 15, 2020
Dong Soo SuhKi Hyung Kim
Frontiers in Bioengineering and Biotechnology

Biophysical Control of Bile Duct Epithelial Morphogenesis in Natural and Synthetic Scaffolds

Frontiers in Bioengineering and BiotechnologyJanuary 11, 2020
Anette FunfakSamy Gobaa
Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

Organoid of ovarian cancer: genomic analysis and drug screening

Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of MexicoJanuary 16, 2020
H-D LiuG Lou
Science Advances

Multivariate patterning of human pluripotent cells under perfusion reveals critical roles of induced paracrine factors in kidney organoid development

Science AdvancesJanuary 15, 2020
Nick R GlassJustin J Cooper-White

Trehalose-based Polyethers for Cryopreservation and 3D Cell Scaffolds

BiomacromoleculesJanuary 9, 2020
Diana Diaz-DussanRavin Narain

Mitochondrial Fusion Via OPA1 and MFN1 Supports Liver Tumor Cell Metabolism and Growth

CellsJanuary 18, 2020
Meng LiQiuwei Pan
Cellular and Molecular Gastroenterology and Hepatology

Lactobacillus rhamnosus GG-induced expression of Leptin in the intestine orchestrates epithelial cell proliferation

Cellular and Molecular Gastroenterology and HepatologyDecember 25, 2019
Trevor M DarbyRheinallt M Jones

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