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Organoids & Neurodegeneration

Organoids & Neurodegeneration diagram by Pavoni et al, PLOS One
Pavoni et al, PLOS One

Recently, cerebral organoids derived from induced pluripotent stem (ips) cells have illuminated early developmental events altered by disease processes, and may be a promising avenue for future therapies in neurodegenerative disorders. Here is the latest research on Organoids & Neurodegeneration.

Top 20 most recent papers
Science

Chromatin accessibility dynamics in a model of human forebrain development

ScienceJanuary 25, 2020
Alexandro E TrevinoSergiu P Pașca
2
1
Cell

A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity

CellDecember 31, 2019
Fadi JacobHongjun Song
145
10
6
1
bioRxiv

Regulation of HDAC2-PDX1 by RNF125 defines pancreatic cancer development

bioRxivJanuary 7, 2020
Eerz HasnisZe'ev A Ronai
10
bioRxiv

Resolving brain organoid heterogeneity by mapping single cell genomic data to a spatial reference

bioRxivJanuary 7, 2020
Jonas Simon FleckBarbara Treutlein
53
Cell Stem Cell

Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αv β5 Axis

Cell Stem CellJanuary 21, 2020
Zhe ZhuJeremy N Rich
40
5
bioRxiv

Single cell epigenomic atlas of the developing human brain and organoids

bioRxivDecember 31, 2019
Ryan S ZiffraTomasz J Nowakowski
144
bioRxiv

EZcalcium: Open Source Toolbox for Analysis of Calcium Imaging Data

bioRxivJanuary 2, 2020
Daniel A CantuCarlos Portera-Cailliau
9
Cell Death & Disease

p53 controls genomic stability and temporal differentiation of human neural stem cells and affects neural organization in human brain organoids

Cell Death & DiseaseJanuary 25, 2020
Ana Marin NavarroMargareta Wilhelm
11
bioRxiv

One-stop Microfluidic Assembly of Human Brain Organoids to Model Prenatal Cannabis Exposure

bioRxivJanuary 16, 2020
Zheng AoFeng Guo
1
Stem Cells and Development

Grafted neural progenitor cells persist in the injured site and differentiate neuronally in a rodent model of cardiac arrest-induced global brain ischemia

Stem Cells and DevelopmentJanuary 23, 2020
Patricia MeyerStephen Leib
1
Biochimica Et Biophysica Acta. General Subjects

A novel neuronal organoid model mimicking glioblastoma (GBM) features from induced pluripotent stem cells (iPSC)

Biochimica Et Biophysica Acta. General SubjectsJanuary 25, 2020
Jin Wook HwangAli G Turhan
2
International Journal of Biological Sciences

Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1G93A Mice

International Journal of Biological SciencesJanuary 14, 2020
Qi ZhouRenshi Xu
1
Biopreservation and Biobanking

Brain Organoids: A Promising Living Biobank Resource for Neuroscience Research

Biopreservation and BiobankingJanuary 25, 2020
Shuang LiJunmei Zhou
Expert Opinion on Drug Discovery

Organoid and pluripotent stem cells in Parkinson's disease modeling: an expert view on their value to drug discovery

Expert Opinion on Drug DiscoveryJanuary 5, 2020
Nick MarottaDimitri Krainc
11
1
Microbial Pathogenesis

Localization of Pasteurella multocida antigens in the brains of pigs naturally infected with Pasteurellosis revealing a newer aspect of pathogenesis

Microbial PathogenesisJanuary 14, 2020
Monalisa SahooRajendra Singh
International Journal of Molecular Sciences

Use of 3D Organoids as a Model to Study Idiopathic Form of Parkinson's Disease

International Journal of Molecular SciencesJanuary 25, 2020
Paula ChlebanowskaAnd Marcin Majka
1
International Journal of Molecular Sciences

Progress of Induced Pluripotent Stem Cell Technologies to Understand Genetic Epilepsy

International Journal of Molecular SciencesJanuary 17, 2020
Bruno SterliniAnna Corradi
1
Bulletin of Experimental Biology and Medicine

Specific Roles of JAKs and STAT3 in Functions of Neural Stem Cells and Committed Neuronal Progenitors during Ethanol-Induced Neurodegeneration

Bulletin of Experimental Biology and MedicineJanuary 16, 2020
G N Zyuz'kovV V Zhdanov
The Journal of Law, Medicine & Ethics : a Journal of the American Society of Law, Medicine & Ethics

Moral Limits of Brain Organoid Research

The Journal of Law, Medicine & Ethics : a Journal of the American Society of Law, Medicine & EthicsJanuary 21, 2020
Julian J Koplin, Julian Savulescu
Cell Stem Cell

Self-Organizing 3D Human Trunk Neuromuscular Organoids

Cell Stem CellJanuary 21, 2020
Jorge-Miguel Faustino MartinsMina Gouti
104
4
1

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