Organoids & Neurodegeneration

Recently, cerebral organoids derived from induced pluripotent stem (ips) cells have illuminated early developmental events altered by disease processes, and may be a promising avenue for future therapies in neurodegenerative disorders. Here is the latest research on Organoids & Neurodegeneration.

August 23, 2020
Open Access

Frataxin gene editing rescues Friedreich's ataxia pathology in dorsal root ganglia organoid-derived sensory neurons

Nature Communications
Pietro Giuseppe MazzaraVania Broccoli
September 12, 2020
Open Access

Human Cerebral Organoids Reveal Early Spatiotemporal Dynamics and Pharmacological Responses of UBE3A

Stem Cell Reports
Dilara SenAlbert J Keung
September 9, 2020

Loss of O-GlcNAc transferase in neural stem cells impairs corticogenesis

Biochemical and Biophysical Research Communications
Juanxian ChengHaitao Wu
September 12, 2020
Open Access

Infection of Brain Organoids and 2D Cortical Neurons with SARS-CoV-2 Pseudovirus

Viruses
Sang Ah YiJaecheol Lee
September 9, 2020
Open Access

Human cerebral organoids and consciousness: a double-edged sword

Monash Bioethics Review
Andrea Lavazza
August 28, 2020
Review
Open Access

Human Microphysiological Models of Intestinal Tissue and Gut Microbiome

Frontiers in Bioengineering and Biotechnology
Steven N SteinwayDeok-Ho Kim
August 31, 2020
Review
Open Access

Nrf2/Wnt resilience orchestrates rejuvenation of glia-neuron dialogue in Parkinson's disease

Redox Biology
Bianca Marchetti
September 3, 2020
Open Access

mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex

ELife
Madeline G AndrewsArnold R Kriegstein
August 28, 2020
Review
Open Access

Stem Cells of the Aging Brain

Frontiers in Aging Neuroscience
Alexandra M NicaiseStefano Pluchino
August 26, 2020
Open Access

iPSCs-Derived Platform: A Feasible Tool for Probing the Neurotropism of SARS-CoV-2

ACS Chemical Neuroscience
Xiao-Yuan Mao, Wei-Lin Jin
September 3, 2020
Preprint
Open Access

BrainPhys neuronal medium optimized for imaging and optogenetics in vitro

BioRxiv : the Preprint Server for Biology
M. ZabolockiCedric Bardy
September 17, 2020

Human Organoids for the Study of Retinal Development and Disease

Annual Review of Vision Science
Claire M BellCynthia A Berlinicke
August 23, 2020

Integrative analyses prioritize GNL3 as a risk gene for bipolar disorder

Molecular Psychiatry
Qingtuan MengChao Chen
August 22, 2020

Multi-walled carbon nanotubes decrease neuronal NO synthase in 3D brain organoids

The Science of the Total Environment
Ying JiangYi Cao
August 31, 2020

Delay of gCJD aggravation in sick TgMHu2ME199K mice by combining NPC transplantation and Nano-PSO administration

Neurobiology of Aging
Kati FridRuth Gabizon
September 17, 2020
Open Access

Generation of self-organized sensory ganglion organoids and retinal ganglion cells from fibroblasts

Science Advances
Dongchang XiaoMengqing Xiang
August 31, 2020

POLYBENZIMIDAZOLE NANOFIBERS FOR NEURAL STEM CELL CULTURE

Materials Today. Chemistry
Fábio F F GarrudoRobert J Linhardt

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