Organoids & Neurodegeneration

Recently, cerebral organoids derived from induced pluripotent stem (ips) cells have illuminated early developmental events altered by disease processes, and may be a promising avenue for future therapies in neurodegenerative disorders. Here is the latest research on Organoids & Neurodegeneration.

June 17, 2020

Alpha-Synuclein Inclusion Formation in Human Oligodendrocytes

Biomolecules & Therapeutics
Ye-Seul YoonHe-Jin Lee
July 1, 2020

Neural In Vitro Models for Studying Substances Acting on the Central Nervous System

Handbook of Experimental Pharmacology
Ellen FritscheBarbara Viviani
June 9, 2020
Review
Open Access

Midbrain Organoids: A New Tool to Investigate Parkinson's Disease

Frontiers in Cell and Developmental Biology
Lisa M Smits, Jens Christian Schwamborn
June 17, 2020

Spinal Cord Injury Leads to Hippocampal Glial Alterations and Neural Stem Cell Inactivation

Cellular and Molecular Neurobiology
Ignacio JureFlorencia Labombarda
June 20, 2020
Preprint
Open Access

Lineage recording reveals dynamics of cerebral organoid regionalization

BioRxiv : the Preprint Server for Biology
Z. HeBarbara Treutlein
June 13, 2020

Modeling and Rescue of RP2 Retinitis Pigmentosa Using iPSC-Derived Retinal Organoids

Stem Cell Reports
Amelia LaneMichael E Cheetham
June 6, 2020
Open Access

EZcalcium: Open-Source Toolbox for Analysis of Calcium Imaging Data

Frontiers in Neural Circuits
Daniel A CantuCarlos Portera-Cailliau
June 27, 2020
Review
Open Access

MAP/ERK Signaling in Developing Cognitive and Emotional Function and Its Effect on Pathological and Neurodegenerative Processes

International Journal of Molecular Sciences
Héctor Albert-GascóFrancisco E Olucha-Bordonau
June 9, 2020
Review
Open Access

Hydrogels Derivatized With Cationic Moieties or Functional Peptides as Efficient Supports for Neural Stem Cells

Frontiers in Neuroscience
Kristin GlotzbachAndreas Faissner
June 14, 2020

Machine learning-assisted neurotoxicity prediction in human midbrain organoids

Parkinsonism & Related Disorders
Anna Sophia MonzelJens Christian Schwamborn
June 13, 2020
Review
Open Access

In vitro Models of Neurodegenerative Diseases

Frontiers in Cell and Developmental Biology
Anna SlanziGabriela Constantin
June 11, 2020
Open Access

Transplantation of induced neural stem cells (iNSCs) into chronically demyelinated corpus callosum ameliorates motor deficits

Acta Neuropathologica Communications
Genevieve M SullivanRegina C Armstrong
June 25, 2020

Astrocyte-Derived Exosomes in an iPSC Model of Bipolar Disorder

Advances in Neurobiology
D AttiliK S O'Shea

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