Feed Preview

Fast Growing


Organoids diagram by Wang et al, PLOS One
Wang et al, PLOS One

Organoids are three-dimensional structures derived from adult or embryonic stem cells, tissues, or tumors, that enable the mimicry of in vivo architecture in tissue culture. Here is the latest research on organoids.

Top 20 most recent papers
Journal of Hepatology

Novel patient-derived preclinical models of liver cancer

Journal of HepatologyJanuary 20, 2020
Erin BresnahanAmaia Lujambio
Expert Opinion on Biological Therapy

Bioengineering strategies for nephrologists: kidney was not built in a day

Expert Opinion on Biological TherapyJanuary 24, 2020
Anna Julie PeiredElena Lazzeri
Cell Stem Cell

Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αv β5 Axis

Cell Stem CellJanuary 21, 2020
Zhe ZhuJeremy N Rich

Lineage reversion drives WNT independence in intestinal cancer

bioRxivJanuary 23, 2020
Teng HanLukas E Dow
Cell Stem Cell

Organoids as Oracles for Precision Medicine in Rectal Cancer

Cell Stem CellJanuary 18, 2020
Kevin S KolahiCalvin J Kuo

Fast and efficient generation of knock-in human organoids using homology-independent CRISPR/Cas9 precision genome editing

bioRxivJanuary 15, 2020
Benedetta ArtegianiHans Clevers

3D-Cell-Annotator: an open-source active surface tool for single cell segmentation in 3D microscopy images

BioinformaticsJanuary 18, 2020
Ervin A TasnadiPeter Horvath
Methods and Applications in Fluorescence

Optimization of FLIM imaging, fitting and analysis for auto-fluorescent NAD(P)H and FAD in cells and tissues

Methods and Applications in FluorescenceJanuary 24, 2020
Ruofan CaoAmmasi Periasamy
Nature Communications

Generation of mesenchyme free intestinal organoids from human induced pluripotent stem cells

Nature CommunicationsJanuary 12, 2020
Aditya MithalGustavo Mostoslavsky
JCI Insight

Interleukin-13 disrupts type 2 pneumocyte stem cell activity

JCI InsightJanuary 17, 2020
Kristen M GlisinskiChristina E Barkauskas

Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model

ELifeJanuary 15, 2020
Magdalena KasendraKatia Karalis
Journal of Pharmacological and Toxicological Methods

Human cardiac ventricular organoid chambers and tissue strips from pluripotent stem cells as a two-tiered assay for inotropic responses: A blinded validation

Journal of Pharmacological and Toxicological MethodsJanuary 23, 2020
Wendy KeungRonald A Li
Cellular and Molecular Gastroenterology and Hepatology

SIRT2 contributes to the regulation of intestinal cell proliferation and differentiation

Cellular and Molecular Gastroenterology and HepatologyJanuary 20, 2020
Chang LiB Mark Evers

iPS, organoids and 3D models as advanced tools for in vitro toxicology

ALTEXJanuary 22, 2020
Nathalie SteimbergDiego Baderna

WNT and inflammatory signaling distinguish human Fallopian tube epithelial cell populations

bioRxivJanuary 16, 2020
Ian M. RoseAlexander Yu. Nikitin
Clinical Oncology : a Journal of the Royal College of Radiologists

Patient-Derived Organoids: Promises, Hurdles and Potential Clinical Applications

Clinical Oncology : a Journal of the Royal College of RadiologistsJanuary 14, 2020
S Hedayat, N Valeri

One-stop Microfluidic Assembly of Human Brain Organoids to Model Prenatal Cannabis Exposure

bioRxivJanuary 16, 2020
Zheng AoFeng Guo
Quantitative Imaging in Medicine and Surgery

Characterizing optical coherence tomography speckle fluctuation spectra of mammary organoids during suppression of intracellular motility

Quantitative Imaging in Medicine and SurgeryJanuary 21, 2020
Lin YangAmy L Oldenburg

Salmonella Enteritidis Effector AvrA suppresses autophagy by reducing Beclin-1 protein

bioRxivJanuary 14, 2020
Yang JiaoJun Sun

Isolation and long-term expansion of a single adult human renal epithelial cell with efficient kidney regeneration capacity

bioRxivJanuary 23, 2020
Yujia WangWei Zuo

See more papers from this feed

Related Feeds

Adult Kidney Organoids at Single Cell Resolution

Single-cell RNA sequencing of the adult human kidney transcriptome can provide molecular information about cell-specific responses to environmental variables and disease states. This information can provide a dataset to benchmark human kidney organoids. Discover the latest research on adult kidney organoids at single cell resolution here.

Adult Stem Cells

Adult stem cells reside in unique niches that provide vital cues for their survival, self-renewal, and differentiation. They hold great promise for use in tissue repair and regeneration as a novel therapeutic strategies. Here is the latest research.

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.

Artificial Cell Models

This feed focuses on biomimetrics, synthetic biology and bio- and tissue-engineering approaches used for modeling human diseases.

Artificial Heart & Ventricular Assist Devices

Total artificial hearts (TAH) and ventricular assist devices (VADs) provide cardiac support for patients with end-stage heart disease and have significantly improved the survival of these patients. Discover the latest research on Artificial Heart and Ventricular Assist Devices here.

Autoimmune Disease Therapy

In autoimmune diseases, the immune system responds and attacks self-antigens and damages or impairs the function of the tissues. The treatment for autoimmune diseases often involves immunosuppressive agents, but newer treatments are being investigated. Discover the latest research on autoimmune disease therapy here.

Biomaterial Engineering

Advances in biomaterial engineering have permitted the development of sophisticated drug-releasing materials with a biomimetic 3D support that allow a better control of the microenvironment of transplanted cells. Here is the latest research.

Brain Organoids in Disease Modeling

Brain organoids are used to represent an in vitro model of the human brain. These brain organoids are derived from three-dimensional human pluripotent stem cells and can be used to help study brain biology, early brain development and different brain diseases. Discover the latest research on brain organoids in disease modeling here.

CFTR Mutant Structural Therapy

Over 1700 different mutations in the CFTR genes have been shown to cause cystic fibrosis. Here is the latest research on structural therapy for CFTR mutants.

CRISPR Genome Editing & Therapy

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of this system for gene editing and therapy in human diseases.

© 2020 Meta ULC. All rights reserved