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Organoids

Organoids diagram by Wang et al, PLOS One
Wang et al, PLOS One

Organoids are three-dimensional structures derived from adult or embryonic stem cells, tissues, or tumors, that enable the mimicry of in vivo architecture in tissue culture. Here is the latest research on organoids.

Top 20 most recent papers
Journal of Hepatology

Novel patient-derived preclinical models of liver cancer

Journal of HepatologyJanuary 20, 2020
Erin BresnahanAmaia Lujambio
Expert Opinion on Biological Therapy

Bioengineering strategies for nephrologists: kidney was not built in a day

Expert Opinion on Biological TherapyJanuary 24, 2020
Anna Julie PeiredElena Lazzeri
Cell Stem Cell

Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αv β5 Axis

Cell Stem CellJanuary 21, 2020
Zhe ZhuJeremy N Rich
41
5
bioRxiv

Lineage reversion drives WNT independence in intestinal cancer

bioRxivJanuary 23, 2020
Teng HanLukas E Dow
Cell Stem Cell

Organoids as Oracles for Precision Medicine in Rectal Cancer

Cell Stem CellJanuary 18, 2020
Kevin S KolahiCalvin J Kuo
7
bioRxiv

Fast and efficient generation of knock-in human organoids using homology-independent CRISPR/Cas9 precision genome editing

bioRxivJanuary 15, 2020
Benedetta ArtegianiHans Clevers
18
Bioinformatics

3D-Cell-Annotator: an open-source active surface tool for single cell segmentation in 3D microscopy images

BioinformaticsJanuary 18, 2020
Ervin A TasnadiPeter Horvath
9
1
Methods and Applications in Fluorescence

Optimization of FLIM imaging, fitting and analysis for auto-fluorescent NAD(P)H and FAD in cells and tissues

Methods and Applications in FluorescenceJanuary 24, 2020
Ruofan CaoAmmasi Periasamy
Nature Communications

Generation of mesenchyme free intestinal organoids from human induced pluripotent stem cells

Nature CommunicationsJanuary 12, 2020
Aditya MithalGustavo Mostoslavsky
50
6
2
JCI Insight

Interleukin-13 disrupts type 2 pneumocyte stem cell activity

JCI InsightJanuary 17, 2020
Kristen M GlisinskiChristina E Barkauskas
13
2
ELife

Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model

ELifeJanuary 15, 2020
Magdalena KasendraKatia Karalis
15
12
Journal of Pharmacological and Toxicological Methods

Human cardiac ventricular organoid chambers and tissue strips from pluripotent stem cells as a two-tiered assay for inotropic responses: A blinded validation

Journal of Pharmacological and Toxicological MethodsJanuary 23, 2020
Wendy KeungRonald A Li
Cellular and Molecular Gastroenterology and Hepatology

SIRT2 contributes to the regulation of intestinal cell proliferation and differentiation

Cellular and Molecular Gastroenterology and HepatologyJanuary 20, 2020
Chang LiB Mark Evers
2
ALTEX

iPS, organoids and 3D models as advanced tools for in vitro toxicology

ALTEXJanuary 22, 2020
Nathalie SteimbergDiego Baderna
bioRxiv

WNT and inflammatory signaling distinguish human Fallopian tube epithelial cell populations

bioRxivJanuary 16, 2020
Ian M. RoseAlexander Yu. Nikitin
3
Clinical Oncology : a Journal of the Royal College of Radiologists

Patient-Derived Organoids: Promises, Hurdles and Potential Clinical Applications

Clinical Oncology : a Journal of the Royal College of RadiologistsJanuary 14, 2020
S Hedayat, N Valeri
1
bioRxiv

One-stop Microfluidic Assembly of Human Brain Organoids to Model Prenatal Cannabis Exposure

bioRxivJanuary 16, 2020
Zheng AoFeng Guo
1
Quantitative Imaging in Medicine and Surgery

Characterizing optical coherence tomography speckle fluctuation spectra of mammary organoids during suppression of intracellular motility

Quantitative Imaging in Medicine and SurgeryJanuary 21, 2020
Lin YangAmy L Oldenburg
bioRxiv

Salmonella Enteritidis Effector AvrA suppresses autophagy by reducing Beclin-1 protein

bioRxivJanuary 14, 2020
Yang JiaoJun Sun
3
bioRxiv

Isolation and long-term expansion of a single adult human renal epithelial cell with efficient kidney regeneration capacity

bioRxivJanuary 23, 2020
Yujia WangWei Zuo

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