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Oxygenation & Hydroxylation

Oxygenation & Hydroxylation diagram by ~K (Public Domain)
~K (Public Domain)

Oxygenation is a chemical production that introduces oxygen atom into an organic compound. Hydroxylation is a chemical process that introduces a hydroxyl group (-OH) into an organic compound. In biochemistry, hydroxylation reactions are often facilitated by enzymes called hydroxylases. Cytochrome P450 (CYP) enzymes are expressed mainly in the liver and are active in mono-oxygenation and hydroxylation of various xenobiotics, including drugs and alcohols, as well as that of endogenous compounds such as steroids, bile acids, prostaglandins, leukotrienes and biogenic amines. Here is the latest research.

Top 20 most recent papers
Open Forum Infectious Diseases

Patients with Idiopathic Pulmonary Nontuberculous Mycobacterial Disease Have Normal Th1/Th2 Cytokine Responses but Diminished Th17 Cytokine and Enhanced Granulocyte-Macrophage Colony-Stimulating Factor Production

Open Forum Infectious DiseasesDecember 1, 2019
Un-In WuSteven M. Holland
Journal of Virology

Trypsin treatment unlocks barrier for zoonotic bat coronaviruses infection

Journal of VirologyDecember 4, 2019
Vineet D. MenacheryRalph Steven Baric
9
Intensive Care Medicine Experimental

Esmolol for cardioprotection during resuscitation with adrenaline in an ischaemic porcine cardiac arrest model

Intensive Care Medicine ExperimentalDecember 4, 2019
Hilde KarlsenTheresa Mariero Olasveengen
Journal of Pain Research

Neuroimaging Of Cold Allodynia Reveals A Central Disinhibition Mechanism Of Pain

Journal of Pain ResearchNovember 11, 2019
Julia ForstenpointnerRalf Baron
Chemical Science

Fluorescent probes towards selective cathepsin B detection and visualization in cancer cells and patient samples

Chemical ScienceSeptember 28, 2019
Marcin PorebaGuy S Salvesen
The Journal of Steroid Biochemistry and Molecular Biology

Obesity and Leptin Influence Vitamin D Metabolism and Action in Human Marrow Stromal Cells

The Journal of Steroid Biochemistry and Molecular BiologyDecember 3, 2019
Jing LiJulie Glowacki
The Journal of Biological Chemistry

Beating tissue factor at its own game: Design and properties of a soluble tissue factor-independent coagulation factor VIIa

The Journal of Biological ChemistryDecember 4, 2019
Anders R SorensenPrafull S Gandhi
1
Minerva anestesiologica

A noninvasive postoperative clinical score to identify patients at risk for postoperative pulmonary complications: the airtest score

Minerva anestesiologicaDecember 4, 2019
Carlos FerrandoIndividualized PeRioperative Openlung VEntilation (iPROVE) Network
Journal of Cardiac Surgery

Stroke risk following implantation of current generation centrifugal flow left ventricular assist devices

Journal of Cardiac SurgeryDecember 6, 2019
Yuting P ChiangCarmelo A Milano
The Journal of Immunology : Official Journal of the American Association of Immunologists

Extremely Preterm Infants Have Significant Alterations in Their Conventional T Cell Compartment during the First Weeks of Life

The Journal of Immunology : Official Journal of the American Association of ImmunologistsDecember 4, 2019
Khaleda Rahman QaziEva Sverremark Ekström
ELife

Homeostatic control of cell wall hydrolysis by the WalRK two-component signaling pathway in Bacillus subtilis

ELifeDecember 6, 2019
Genevieve S DobihalDavid Z Rudner
Bio-protocol

Antisense Oligodeoxynucleotide Perfusion Blocks Gene Expression of Synaptic Plasticity-related Proteins without Inducing Compensation in Hippocampal Slices

Bio-protocolOctober 5, 2019
Panayiotis TsokasTodd Charlton Sacktor
1
The Journal of Steroid Biochemistry and Molecular Biology

Differential Quantitative Proteomics Reveals Key Proteins Related to Phenotypic Changes of Breast Cancer Cells Expressing Progesterone Receptor A

The Journal of Steroid Biochemistry and Molecular BiologyDecember 3, 2019
Prangwan PateetinViroj Boonyaratanakornkit
Annals of Translational Medicine

Functional magnetic resonance imaging-based assessment of terlipressin vs octreotide on renal function in cirrhotic patients with acute variceal bleeding (CHESS1903): study protocol of a multicenter randomized controlled trial

Annals of Translational MedicineOctober 1, 2019
Xinwen YanXiao-Long Qi
Journal of Neurology, Neurosurgery, and Psychiatry

Peripheral blood helper T cell profiles and their clinical relevance in MOG-IgG-associated and AQP4-IgG-associated disorders and MS

Journal of Neurology, Neurosurgery, and PsychiatryDecember 5, 2019
Jia LiuSatoshi Kuwabara
Archives of Biochemistry and Biophysics

Novel insights into oxidation of fatty acids and fatty alcohols by cytochrome P450 monooxygenase CYP4B1

Archives of Biochemistry and BiophysicsDecember 1, 2019
Florian A ThesselingMarco Girhard
The Journal of Organic Chemistry

Boron-Catalyzed N-Alkylation of Arylamines and Arylamides with Benzylic Alcohols

The Journal of Organic ChemistryDecember 5, 2019
Murali Mohan GuruBiplab Maji
Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

There and Back Again: Roller Pumps Versus Centrifugal Technology in Infants on Extracorporeal Membrane Oxygenation

Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care SocietiesDecember 1, 2019
Heidi J Dalton, Aparna U Hoskote
Biomaterials Science

A near-infrared laser and H2 O2 activated bio-nanoreactor for enhanced photodynamic therapy of hypoxic tumors

Biomaterials ScienceDecember 6, 2019
Liming DengZhi-gang Wang
Brain Structure & Function

Cholecystokinin in the central nervous system of the sea lamprey Petromyzon marinus: precursor identification and neuroanatomical relationships with other neuronal signalling systems

Brain Structure & FunctionDecember 5, 2019
Daniel Sobrido-CameánAntón Barreiro-Iglesias

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