p53 Pathway

p53 is a transcription factor that is involved in several cellular processes, including cell cycle arrest, cellular apoptosis, cell death and cell senescence. Mutations in the wild type p53 gene has been implicated in a significant number of cancers. Here is the latest research on p53 pathways.

August 5, 2020

Light-emitting diode irradiation induces AKT/mTOR-mediated apoptosis in human pancreatic cancer cells and xenograft mouse model

Journal of Cellular Physiology
Young Mi KimJi Hyeon Ryu
August 2, 2020

Aurora kinases and DNA damage response

Mutation Research
Hoi Tang Ma, Randy Y C Poon
August 2, 2020
Open Access

Effect of methoxy stilbenes-analogs of resveratrol-on the viability and induction of cell cycle arrest and apoptosis in human myeloid leukemia cells

Molecular and Cellular Biochemistry
Małgorzata Zielińska-PrzyjemskaWanda Baer-Dubowska
August 3, 2020

Study on antitumor activities of the chrysin-chromene-spirooxindole on Lewis lung carcinoma C57BL/6 mice in vivo

Bioorganic & Medicinal Chemistry Letters
Wen-Hui ZhangYing Zhou
August 1, 2020
Open Access

PI3K/Akt and ERK1/2 Signalling Are Involved in Quercetin-Mediated Neuroprotection against Copper-Induced Injury

Oxidative Medicine and Cellular Longevity
Klara ZubčićMaja Jazvinšćak Jembrek
August 5, 2020

Ginkgo biloba Extract Mechanism Inhibits Hepatocellular Carcinoma through the Nuclear Factor-κB/p53 Signaling Pathway

Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society for Environmental Toxicology and Cancer
Ruike WangYing Shao
August 2, 2020
Open Access

Expression profiling of human milk derived exosomal microRNAs and their targets in HIV-1 infected mothers

Scientific Reports
Muhammad Atif ZahoorKenneth L Rosenthal
August 7, 2020
Open Access

Identification of key genes and pathways involved in vitiligo development based on integrated analysis

Zixian LeiXiaojing Kang
August 8, 2020

Chrysin Suppresses HT-29 Cell Death Induced by Diclofenac through Apoptosis and Oxidative Damage

Nutrition and Cancer
Seda Nur Özbolat, Adnan Ayna
August 7, 2020
Open Access

A Switch in p53 Dynamics Marks Cells That Escape from DSB-Induced Cell Cycle Arrest

Cell Reports
Michael TsabarGalit Lahav

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