p53 Pathway

p53 is a transcription factor that is involved in several cellular processes, including cell cycle arrest, cellular apoptosis, cell death and cell senescence. Mutations in the wild type p53 gene has been implicated in a significant number of cancers. Here is the latest research on p53 pathways.

May 28, 2020
Open Access

Guidelines for the Li-Fraumeni and heritable TP53-related cancer syndromes

European Journal of Human Genetics : EJHG
Thierry FrebourgEuropean Reference Network GENTURIS
May 29, 2020

Circular RNA hsa_circ_0000376 Participates in Tumorigenesis of Breast Cancer by Targeting miR-1285-3p

Technology in Cancer Research & Treatment
Ziqi PengFeng Jin
May 28, 2020

Identification of Potential Diagnostic and Prognostic Pseudogenes in Hepatocellular Carcinoma Based on Pseudogene-miRNA-mRNA Competitive Network

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Lijun YanJixiang Wu
May 27, 2020
Open Access

An In Vitro Study on the Cytotoxicity and Genotoxicity of Silver Sulfide Quantum Dots Coated with Meso-2,3-dimercaptosuccinic Acid

Turkish Journal of Pharmaceutical Sciences
Deniz Özkan VardarNursen Başaran
May 29, 2020

p60-katanin: a novel interacting partner for p53

Molecular Biology Reports
Sirin Korulu, Aysegul Yildiz
May 28, 2020
Open Access

Down-Regulation of miR-23a-3p Mediates Irradiation-Induced Neuronal Apoptosis

International Journal of Molecular Sciences
Boris SabirzhanovBogdan A Stoica
May 27, 2020

Atg5-mediated autophagy controls apoptosis/anoikis via p53/Rb pathway in naked mole-rat fibroblasts

Biochemical and Biophysical Research Communications
Junhyeong KimMasato Okada
May 28, 2020
Review
Open Access

Vitamin D in Triple-Negative and BRCA1-Deficient Breast Cancer-Implications for Pathogenesis and Therapy

International Journal of Molecular Sciences
Janusz BlasiakCezary Chojnacki
June 3, 2020
Review

Hepatoprotective effect of plant polysaccharides from natural resources: A review of the mechanisms and structure-activity relationship

International Journal of Biological Macromolecules
Jialin QuDong Shang
June 3, 2020

Olig2 SUMOylation protects against genotoxic damage response by antagonizing p53 gene targeting

Cell Death and Differentiation
Huiqing LiuYong Li

Sign up to follow this feed and discover related papers.

Related Feeds

Apoptosis in Cancer

Apoptosis is an important mechanism in cancer. By evading apoptosis, tumors can continue to grow without regulation and metastasize systemically. Many therapies are evaluating the use of pro-apoptotic activation to eliminate cancer growth. Here is the latest research on apoptosis in cancer.

Autophagy & Metabolism

Autophagy preserves the health of cells and tissues by replacing outdated and damaged cellular components with fresh ones. In starvation, it provides an internal source of nutrients for energy generation and, thus, survival. A powerful promoter of metabolic homeostasis at both the cellular and whole-animal level, autophagy prevents degenerative diseases. It does have a downside, however--cancer cells exploit it to survive in nutrient-poor tumors.

Autophagy: Cancer & Parkinson

Autophagy leads to degradation of damaged proteins and organelles by the lysosome. Impaired autophagy has been implicated in several diseases. Here is the role of autophagy in cancer and Parkinson’s.

Biophysics of Adhesion

Alterations in cell adhesion can disrupt important cellular processes and lead to a variety of diseases, including cancer and arthritis. It is also essential for infectious organisms, such as bacteria or viruses, to cause diseases. Understanding the biophysics of cell adhesion can help understand these diseases. Discover the latest research on the biophysics of adhesion here.

Cancer Biology: Molecular Imaging

Molecular imaging enables noninvasive imaging of key molecules that are crucial to tumor biology. Discover the latest research in molecular imaging in cancer biology in this feed.

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.

Cancer Metabolism

In order for cancer cells to maintain rapid, uncontrolled cell proliferation, they must acquire a source of energy. Cancer cells acquire metabolic energy from their surrounding environment and utilize the host cell nutrients to do so. Here is the latest research on cancer metabolism.

Cell Migration in Cancer and Metastasis

Migration of cancer cells into surrounding tissue and the vasculature is an initial step in tumor metastasis. Discover the latest research on cell migration in cancer and metastasis here.

Cell Signaling by Tyrosine Kinases

Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. RTKs have been shown not only to be key regulators of normal cellular processes but also to have a critical role in the development and progression of many types of cancer. Discover the latest research on cell signaling and RTK here.

Circadian Clock & Cancer

Circadian rhythms are natural, internal processes that regulate the sleep-wake cycle. Chronic disruptions in circadian rhythms have been associated with the development of a variety of diseases including cancer. Here is the latest research on circadian rhythms and cancer.

© 2020 Meta ULC. All rights reserved
/feed-previews/p53-pathway/be357799-b9f8-42fb-9fff-4f7d301cea00