Pain signaling pathways involve many molecular components that could potentially be targets for pharmacotherapeutic interventions. Discover the latest research on nociception and signal transduction through nocireceptors here.
G-protein-coupled receptors (GPCRs), the largest family of integral membrane proteins, participate in the regulation of many physiological functions and are the targets of approximately 30% of currently marketed drugs. Here is the latest research.
GPCRs are membrane receptors implicated in the pathophysiology of various diseases. Several GPCRs, including GLP-1 receptor, glucagon receptor, and adiponectin receptor, are also involved in metabolic regulation and homeostasis. Here is the latest research.
G-protein coupled receptors (GPCRs) are membrane receptors implicated in the pathophysiology of various diseases, including neurodegenerative disorders, infectious diseases, and cancer. Here is the latest research on GPCR signaling pathway.
Hereditary optic atrophy is a mitochondrially inherited disease that results in bilateral subacute loss of central vision due to degeneration of retinal ganglion cells and the optic nerve. Here is the latest research.
Microglia are found throughout the brain and spinal cord and are the resident macrophages of the CNS. There have been investigations into the involvement of microglia in somatosensory sensory circuits within the spinal cord and associated diseases. Here is the latest research on microglia and spinal somatosensory circuits.