Pain Signaling

Pain signaling pathways involve many molecular components that could potentially be targets for pharmacotherapeutic interventions. Discover the latest research on nociception and signal transduction through nocireceptors here.

January 12, 2021
Open Access

Chronic Tear Deficiency Sensitizes Transient Receptor Potential Vanilloid 1-Mediated Responses in Corneal Sensory Nerves

Frontiers in Cellular Neuroscience
Takayoshi MasuokaTakaharu Ishibashi
January 14, 2021
Open Access

Inflammatory Mediators and Pain in Endometriosis: A Systematic Review

Nikolaos MachairiotisNikolaos Thomakos
January 14, 2021
Open Access

Stiff-Person Syndrome: A Treatment Update and New Directions

Juan Fernando OrtizGustavo Moya
January 13, 2021

Future in regional anesthesia and pain medicine: the pharmacological view

Minerva anestesiologica
Stanley Jablonski, Philipp Lirk
January 12, 2021
Open Access

Angiotensin Type 2 Receptors: Painful, or Not?

Frontiers in Pharmacology
Lakshmi Pulakat, Colin Sumners
January 11, 2021

Pain, depression and quality of life in adults with MOG-antibody associated disease

European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies
Susanna AsseyerNeuromyelitis Optica Study Group (NEMOS)
January 15, 2021
Open Access

Manipulating Pharmacodynamic Efficacy with Agonist + Antagonist Mixtures:In Vitro and In Vivo Studies with Opioids and Cannabinoids

The Journal of Pharmacology and Experimental Therapeutics
Dana E SelleyS Stevens Negus
January 13, 2021

Altered nociception in Alzheimer's disease is associated with STEP signaling

Zhung-Fu LeeIrene Hanjuo Cheng
January 15, 2021
Open Access

The VLPFC vs. the DLPFC in down-regulating social pain using reappraisal and distraction strategies

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Jun ZhaoDandan Zhang
January 12, 2021

Ultrasound-guided fascial plane blocks of the chest wall: a state-of-the-art review

K J ChinA Pawa
January 14, 2021

Ketamine inhibits neuronal differentiation by regulating brain-derived neurotrophic factor (BDNF) signaling

Toxicology in Vitro : an International Journal Published in Association with BIBRA
Sheng LiuXuejie Fei
January 13, 2021
Open Access

Antinociceptive Effect of an Aqueous Extract and Essential Oil from Baccharis heterophylla

Erika Castillejos-RamírezRachel Mata
January 10, 2021

The Role of Mrgprs in Pain

Neuroscience Letters
Dustin P Green
January 13, 2021

Future in regional anesthesia and pain medicine: neuropathic pain and robotic limbs

Minerva anestesiologica
Giovanni Di PinoMax Ortiz-Catalan
January 15, 2021

Pain in rheumatic diseases : What can biologics and JAK inhibitors offer?

Zeitschrift für Rheumatologie
G Pongratz
January 13, 2021

A subset of spinal dorsal horn interneurons crucial for gating touch-evoked pain-like behavior

Proceedings of the National Academy of Sciences of the United States of America
Ryoichi TashimaMakoto Tsuda
January 10, 2021
Open Access

A capsaicinoid-based soft drug, AG1529, for attenuating TRPV1-mediated histaminergic and inflammatory sensory neuron excitability

Scientific Reports
Magdalena Nikolaeva-KolevaAntonio Ferrer-Montiel
January 11, 2021

Functional Characterization of Nociceptive Mechanisms Involved in Fibromyalgia and Electroacupuncture

Brain Research
Bernice Lottering, Yi-Wen Lin

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