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Parkinson's Disease: Alpha-Synuclein (MDS)

Parkinson's Disease: Alpha-Synuclein (MDS) diagram by StudioMolekuul, Shutterstock
StudioMolekuul, Shutterstock

Alpha-synuclein is an integral component of Lewy bodies which are comprised of protein clumps and are a pathological hallmark of Parkinson’s disease. Here is the latest research.

Top 20 most recent papers
Parkinsonism & Related Disorders

Peripheral alpha-synuclein levels in patients with genetic and non-genetic forms of Parkinson's disease

Parkinsonism & Related DisordersApril 3, 2020
Evangelia EmmanouilidouLeonidas Stefanis
9
Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics

Long Noncoding RNA POU3F3 and α-Synuclein in Plasma L1CAM Exosomes Combined with β-Glucocerebrosidase Activity: Potential Predictors of Parkinson's Disease

Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeuticsApril 3, 2020
Jing ZouAnding Xu
1
Brain : a Journal of Neurology

Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson's disease

Brain : a Journal of NeurologyMarch 24, 2020
Yaping ChuJeffrey H Kordower
13
1
13
1
bioRxiv

Tau accumulates in Crohn's disease gut

bioRxivMarch 18, 2020
Alice PrigentMalvyne Rolli-Derkinderen
11
Acta Neuropsychiatrica

Systematic review of gene expression studies in people with Lewy Body Dementia

Acta NeuropsychiatricaMarch 18, 2020
Anisa Chowdhury, Anto P Rajkumar
4
Cells

The Promise and Challenges of Developing miRNA-Based Therapeutics for Parkinson's Disease

CellsApril 5, 2020
Simoneide S Titze-de-AlmeidaRicardo Titze-de-Almeida
2
Nature Reviews. Neurology

Protein transmission in neurodegenerative disease

Nature Reviews. NeurologyMarch 24, 2020
Chao PengVirginia M-Y Lee
95
1
International Journal of Biological Macromolecules

The status of the terminal regions of α-synuclein in different forms of aggregates during fibrillization

International Journal of Biological MacromoleculesApril 3, 2020
Amir Tayaranian MarvianDina Morshedi
8
Nature Reviews. Molecular Cell Biology

Lipids as the key to understanding α-synuclein behaviour in Parkinson disease

Nature Reviews. Molecular Cell BiologyMarch 24, 2020
Roni Stok, Avraham Ashkenazi
11
1
Brain : a Journal of Neurology

Variants in saposin D domain of prosaposin gene linked to Parkinson's disease

Brain : a Journal of NeurologyMarch 24, 2020
Yutaka OjiNobutaka Hattori
23
5
International Journal of Molecular Sciences

Fatty Acid Binding Protein 3 Enhances the Spreading and Toxicity of α-Synuclein in Mouse Brain

International Journal of Molecular SciencesMarch 27, 2020
Yasushi YabukiKohji Fukunaga
1
European Journal of Medicinal Chemistry

Non-polyphenolic natural inhibitors of amyloid aggregation

European Journal of Medicinal ChemistryMarch 17, 2020
Liang MaKun Huang
1

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