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Parkinson's Disease: Alpha-Synuclein

Parkinson's Disease: Alpha-Synuclein diagram by StudioMolekuul, Shutterstock
StudioMolekuul, Shutterstock

Alpha-synuclein is an integral component of Lewy bodies which are comprised of protein clumps and are a pathological hallmark of Parkinson’s disease. Here is the latest research.

Top 20 most recent papers
Progress in Brain Research

Prodromal PD: A new nosological entity

Progress in Brain ResearchApril 6, 2020
Eva SchaefferDaniela Berg
Progress in Brain Research

Selective neuronal vulnerability in Parkinson's disease

Progress in Brain ResearchApril 6, 2020
Patricia Gonzalez-RodriguezD James Surmeier
Progress in Brain Research

Endosomal sorting pathways in the pathogenesis of Parkinson's disease

Progress in Brain ResearchApril 6, 2020
Lindsey A Cunningham, Darren J Moore
Progress in Brain Research

The gut microbiome in Parkinson's disease: A culprit or a bystander?

Progress in Brain ResearchApril 6, 2020
Ali KeshavarzianRoberto Cilia
Progress in Brain Research

Novel approaches to counter protein aggregation pathology in Parkinson's disease

Progress in Brain ResearchApril 6, 2020
Simon R W StottPatrik Brundin
Progress in Brain Research

The role of glia in Parkinson's disease: Emerging concepts and therapeutic applications

Progress in Brain ResearchApril 6, 2020
Katarzyna Z KuterAnna R Carta
Progress in Brain Research

Pathways of protein synthesis and degradation in PD pathogenesis

Progress in Brain ResearchApril 6, 2020
Rebekah G Langston, Mark R Cookson
Brain : a Journal of Neurology

Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson's disease

Brain : a Journal of NeurologyMarch 24, 2020
Yaping ChuJeffrey H Kordower
13
1
Progress in Brain Research

Animal models for preclinical Parkinson's research: An update and critical appraisal

Progress in Brain ResearchApril 6, 2020
M Angela Cenci, Anders Björklund
Progress in Brain Research

Innate and adaptive immune responses in Parkinson's disease

Progress in Brain ResearchApril 6, 2020
Aubrey M SchonhoffAshley S Harms
Cells

The Promise and Challenges of Developing miRNA-Based Therapeutics for Parkinson's Disease

CellsApril 5, 2020
Simoneide S Titze-de-AlmeidaRicardo Titze-de-Almeida
2
Nature Reviews. Neurology

Protein transmission in neurodegenerative disease

Nature Reviews. NeurologyMarch 24, 2020
Chao PengVirginia M-Y Lee
95
1
Progress in Brain Research

Mechanisms of alpha-synuclein toxicity: An update and outlook

Progress in Brain ResearchApril 6, 2020
Inês Caldeira BrásTiago Fleming Outeiro
Progress in Brain Research

What we can learn from iPSC-derived cellular models of Parkinson's disease

Progress in Brain ResearchApril 6, 2020
Maria Claudia CaiazzaRichard Wade-Martins
Progress in Brain Research

New players in basal ganglia dysfunction in Parkinson's disease

Progress in Brain ResearchApril 6, 2020
Sara MeoniElena Moro
Nature Reviews. Molecular Cell Biology

Lipids as the key to understanding α-synuclein behaviour in Parkinson disease

Nature Reviews. Molecular Cell BiologyMarch 24, 2020
Roni Stok, Avraham Ashkenazi
11
1

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