Parkinson's Disease & Autophagy

Autophagy leads to degradation of damaged proteins and organelles by the lysosome. Impaired autophagy has been implicated in several diseases. Here is the role of autophagy in Parkinson’s disease.

December 1, 2021

Phenotypic Assay Leads to Discovery of Mitophagy Inducers with Therapeutic Potential for Parkinson's Disease.

ACS Chemical Neuroscience
Inés MaestroAna Martinez
November 29, 2021

Updates on the Genetics of Parkinson's Disease: Clinical Implications and Future Treatment.

Acta Neurologica Taiwanica
Yung-Tsai ChuRuey-Meei Wu
November 28, 2021
Review
Open Access

Autophagy in α-Synucleinopathies-An Overstrained System.

Cells
Lisa FellnerFrank Edenhofer
November 28, 2021
Review
Open Access

Disruption of Mitochondrial Homeostasis: The Role of PINK1 in Parkinson's Disease.

Cells
Maria VizzielloGianluca Ardolino
November 28, 2021
Review
Open Access

Protein Misfolding and Aggregation: The Relatedness between Parkinson's Disease and Hepatic Endoplasmic Reticulum Storage Disorders.

International Journal of Molecular Sciences
Francisco J Padilla-GodínezMagdalena Guerra-Crespo
November 28, 2021
Review
Open Access

Macroautophagy and Mitophagy in Neurodegenerative Disorders: Focus on Therapeutic Interventions.

Biomedicines
João Duarte MagalhãesAna Cristina Rego
November 28, 2021
Review
Open Access

Mitochondria-Endoplasmic Reticulum Crosstalk in Parkinson's Disease: The Role of Brain Renin Angiotensin System Components.

Biomolecules
Tuladhar SunandaSaravana Babu Chidambaram
November 24, 2021

The increase of α-synuclein and alterations of dynein in A53T transgenic and aging mouse.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
Yiqing WangZenglin Cai
November 21, 2021

FBXO7 triggers caspase 8-mediated proteolysis of the transcription factor FOXO4 and exacerbates neuronal cytotoxicity.

The Journal of Biological Chemistry
Su Hyoun LeeKwang Chul Chung
November 20, 2021
Review

HMGB1 is a Potential and Challenging Therapeutic Target for Parkinson's Disease.

Cellular and Molecular Neurobiology
Yu TianZhaoliang Su
November 18, 2021

CSF MicroRNAs Reveal Impairment of Angiogenesis and Autophagy in Parkinson Disease.

Neurology. Genetics
Alan J FowlerCharbel Moussa
November 15, 2021
Review
Open Access

The Role of GM130 in Nervous System Diseases.

Frontiers in Neurology
Bei HuangXiaoshi Zhu
November 14, 2021
Review
Open Access

Focus on the Small GTPase Rab1: A Key Player in the Pathogenesis of Parkinson's Disease.

International Journal of Molecular Sciences
José Ángel Martínez-MenárguezMónica Tomás
November 14, 2021
Review
Open Access

Neurodegenerative Disorders: Spotlight on Sphingolipids.

International Journal of Molecular Sciences
Frida Mandik, Melissa Vos
November 14, 2021
Open Access

Kaempferol Has Potent Protective and Antifibrillogenic Effects for α-Synuclein Neurotoxicity In Vitro.

International Journal of Molecular Sciences
Masatoshi IndenIsao Hozumi

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