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Parkinson's Disease (Preprints)
#N/AParkinson’s disease is a progressive neurodegenerative disorder that affects movement. This feed focuses on genetic screening approaches and genetic predispositions in Parkinson’s disease.
Top 20 most recent papers
ATF4 regulates neuronal death in models of Parkinson's disease
bioRxivSeptember 30, 2019
Matthew D DemmingsSean P Cregan
8
1
Accurate MS-based Rab10 phosphorylation stoichiometry determination for LRRK2 activity in Parkinson's disease
bioRxivOctober 25, 2019
Özge KarayelMatthias Mann
23
4
Integrated Sequencing & Array Comparative Genomic Hybridization in Familial Parkinson's Disease
bioRxivNovember 11, 2019
Laurie A. RobakJoshua M. Shulman
24
3
The α-synuclein hereditary mutation E46K unlocks a more stable, pathogenic fibril structure
bioRxivDecember 8, 2019
David R. BoyerDavid S. Eisenberg
14
Quantifying normal and parkinsonian gait features from home movies: Practical application of a deep learning–based 2D pose estimator
bioRxivSeptember 25, 2019
Kenichiro SatoTatsushi Toda
4
17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson's disease and progressive supranuclear palsy converge on altered glial regulation
bioRxivNovember 30, 2019
Kathryn R BowlesAlison M. Goate
13
Loss of region-specific glial homeostatic signature in prion diseases
bioRxivOctober 30, 2019
Natallia MakaravaIlia V Baskakov
2
3
Dopamine modulates the size of striatal projection neuron ensembles
bioRxivDecember 5, 2019
Marta MalteseNicolas X Tritsch
105
α-synuclein aggregates induce c-Abl activation and neurodegeneration by a redox stress mechanism
bioRxivNovember 13, 2019
Soumitra GhoshRaymond Alan Swanson
13
Dopamine buffering capacity imaging: A pharmacodynamic fMRI method for staging Parkinson disease
bioRxivOctober 24, 2019
Kevin J BlackJonathan M. Koller
6
2
ERP sources in middle cingulate and precuneus differentiate Parkinson's patients from healthy controls and lingual gyri sources reflect human recombinant EPO effects in a Flanker task
bioRxivDecember 5, 2019
Maria Luisa BringasPedro Antonio Valdés-Sosa
3
A Small-Molecule Activity-Based Probe for Monitoring Ubiquitin C-terminal Hydrolase L1 (UCHL1) Activity in Live Cells and Zebrafish Embryos
bioRxivNovember 1, 2019
Paul P GeurinkHuib Ovaa
1
Selective K-ATP channel-dependent loss of pacemaking in vulnerable nigrostriatal dopamine neurons by α-synuclein aggregates
bioRxivNovember 15, 2019
Poonam ThakurJochen Roeper
18
1
The in situ structure of Parkinson's disease-linked LRRK2
bioRxivNovember 10, 2019
Reika WatanabeElizabeth Villa
164
21
Mutations in Auxilin cause parkinsonism via impaired clathrin-mediated trafficking at the Golgi apparatus and synapse
bioRxivNovember 5, 2019
Dorien A. RoosenMark Robert Cookson
30
Applications of the Microphysiology Systems Database for Experimental ADME-Tox and Disease Models
bioRxivSeptember 25, 2019
Mark E SchurdakAlbert H Gough
1
CHCHD10 OR CHCHD2 ARE NOT REQUIRED FOR HUMAN MOTOR NEURON DIFFERENTIATION IN VITRO BUT MODIFY SYNAPTIC TRANSCRIPTOMES
bioRxivNovember 1, 2019
Sandra HarjuhaahtoHenna Tyynismaa
15
1
Deficits in monitoring self-produced speech in Parkinson's disease
bioRxivOctober 30, 2019
Henry RailoValtteri Kaasinen
7
1
Transgenic mice expressing human alpha-synuclein in noradrenergic neurons develop locus coeruleus pathology and non-motor features of Parkinson's disease
bioRxivNovember 28, 2019
Laura M ButkovichMalú Gámez Tansey
22
Reduction of spontaneous cortical beta bursts in Parkinson's disease is linked to symptom severity
bioRxivSeptember 22, 2019
Mikkel C. VindingDaniel Lundqvist
12
1