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Parkinson's Disease (Preprints)

Parkinson's Disease (Preprints)   diagram by #N/A
#N/A

Parkinson’s disease is a progressive neurodegenerative disorder that affects movement. This feed focuses on genetic screening approaches and genetic predispositions in Parkinson’s disease.

Top 20 most recent papers
bioRxiv

ATF4 regulates neuronal death in models of Parkinson's disease

bioRxivSeptember 30, 2019
Matthew D DemmingsSean P Cregan
8
1
bioRxiv

Accurate MS-based Rab10 phosphorylation stoichiometry determination for LRRK2 activity in Parkinson's disease

bioRxivOctober 25, 2019
Özge KarayelMatthias Mann
23
4
bioRxiv

Integrated Sequencing & Array Comparative Genomic Hybridization in Familial Parkinson's Disease

bioRxivNovember 11, 2019
Laurie A. RobakJoshua M. Shulman
24
3
bioRxiv

The α-synuclein hereditary mutation E46K unlocks a more stable, pathogenic fibril structure

bioRxivDecember 8, 2019
David R. BoyerDavid S. Eisenberg
14
bioRxiv

Quantifying normal and parkinsonian gait features from home movies: Practical application of a deep learning–based 2D pose estimator

bioRxivSeptember 25, 2019
Kenichiro SatoTatsushi Toda
4
bioRxiv

17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson's disease and progressive supranuclear palsy converge on altered glial regulation

bioRxivNovember 30, 2019
Kathryn R BowlesAlison M. Goate
13
bioRxiv

Loss of region-specific glial homeostatic signature in prion diseases

bioRxivOctober 30, 2019
Natallia MakaravaIlia V Baskakov
2
3
bioRxiv

Dopamine modulates the size of striatal projection neuron ensembles

bioRxivDecember 5, 2019
Marta MalteseNicolas X Tritsch
105
bioRxiv

α-synuclein aggregates induce c-Abl activation and neurodegeneration by a redox stress mechanism

bioRxivNovember 13, 2019
Soumitra GhoshRaymond Alan Swanson
13
bioRxiv

Dopamine buffering capacity imaging: A pharmacodynamic fMRI method for staging Parkinson disease

bioRxivOctober 24, 2019
Kevin J BlackJonathan M. Koller
6
2
bioRxiv

ERP sources in middle cingulate and precuneus differentiate Parkinson's patients from healthy controls and lingual gyri sources reflect human recombinant EPO effects in a Flanker task

bioRxivDecember 5, 2019
Maria Luisa BringasPedro Antonio Valdés-Sosa
3
bioRxiv

A Small-Molecule Activity-Based Probe for Monitoring Ubiquitin C-terminal Hydrolase L1 (UCHL1) Activity in Live Cells and Zebrafish Embryos

bioRxivNovember 1, 2019
Paul P GeurinkHuib Ovaa
1
bioRxiv

Selective K-ATP channel-dependent loss of pacemaking in vulnerable nigrostriatal dopamine neurons by α-synuclein aggregates

bioRxivNovember 15, 2019
Poonam ThakurJochen Roeper
18
1
bioRxiv

The in situ structure of Parkinson's disease-linked LRRK2

bioRxivNovember 10, 2019
Reika WatanabeElizabeth Villa
164
21
bioRxiv

Mutations in Auxilin cause parkinsonism via impaired clathrin-mediated trafficking at the Golgi apparatus and synapse

bioRxivNovember 5, 2019
Dorien A. RoosenMark Robert Cookson
30
bioRxiv

Applications of the Microphysiology Systems Database for Experimental ADME-Tox and Disease Models

bioRxivSeptember 25, 2019
Mark E SchurdakAlbert H Gough
1
bioRxiv

CHCHD10 OR CHCHD2 ARE NOT REQUIRED FOR HUMAN MOTOR NEURON DIFFERENTIATION IN VITRO BUT MODIFY SYNAPTIC TRANSCRIPTOMES

bioRxivNovember 1, 2019
Sandra HarjuhaahtoHenna Tyynismaa
15
1
bioRxiv

Deficits in monitoring self-produced speech in Parkinson's disease

bioRxivOctober 30, 2019
Henry RailoValtteri Kaasinen
7
1
bioRxiv

Transgenic mice expressing human alpha-synuclein in noradrenergic neurons develop locus coeruleus pathology and non-motor features of Parkinson's disease

bioRxivNovember 28, 2019
Laura M ButkovichMalú Gámez Tansey
22
bioRxiv

Reduction of spontaneous cortical beta bursts in Parkinson's disease is linked to symptom severity

bioRxivSeptember 22, 2019
Mikkel C. VindingDaniel Lundqvist
12
1

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