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PARP Inhibitors

PARP Inhibitors diagram by StudioMolekuul, Shutterstock
StudioMolekuul, Shutterstock

PARP inhibitors are a novel type of therapeutic agent being investigated for the treatment of some cancer types, particularly targeting tumors that are deficient in the homologous recombination DNA repair pathway. They have shown promise in BRCA mutations in breast cancer. Discover the latest research on PARP inhibitors here.

Top 20 most recent papers
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research

Non-BRCA DNA Damage Repair Gene Alterations and Response to the PARP Inhibitor Rucaparib in Metastatic Castration-Resistant Prostate Cancer: analysis from the phase 2 TRITON2 study

Clinical Cancer Research : an Official Journal of the American Association for Cancer ResearchFebruary 23, 2020
Wassim AbidaSimon Chowdhury
4
Arteriosclerosis, Thrombosis, and Vascular Biology

Novel Long Noncoding RNA, Macrophage Inflammation-Suppressing Transcript (MIST ), Regulates Macrophage Activation During Obesity

Arteriosclerosis, Thrombosis, and Vascular BiologyFebruary 21, 2020
Kenneth StapletonRama Natarajan
4
Haematologica

Exploiting MYC-induced PARPness to target genomic instability in multiple myeloma

HaematologicaFebruary 22, 2020
Daniele CaraccioloPierfrancesco Tassone
1
Free Radical Biology & Medicine

Editorial

Free Radical Biology & MedicineFebruary 18, 2020
Consuelo Borras, Jose Viña
2
International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society

Decision analysis for secondline maintenance treatment of platinum sensitive recurrent ovarian cancer: a review

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer SocietyFebruary 22, 2020
Rebecca ArendRobert Coleman
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research

Targeted brain tumor radiotherapy using an Auger emitter

Clinical Cancer Research : an Official Journal of the American Association for Cancer ResearchFebruary 19, 2020
Giacomo PirovanoThomas Reiner
10
Free Radical Biology & Medicine

Heme Oxygenase-1 in liver transplant ischemia-reperfusion injury: From bench-to-bedside

Free Radical Biology & MedicineFebruary 22, 2020
Hirofumi HiraoJerzy W Kupiec-Weglinski
2
Free Radical Biology & Medicine

Oxidation of cathepsin S by major chemicals of cigarette smoke

Free Radical Biology & MedicineFebruary 22, 2020
Mylène WartenbergGilles Lalmanach
Trends in Cancer

Therapeutic Application of PARP Inhibitors in Neuro-Oncology

Trends in CancerFebruary 18, 2020
Jianfang Ning, Hiroaki Wakimoto
3
1
Free Radical Biology & Medicine

Geniposide protects against sepsis-induced myocardial dysfunction through AMPKα-dependent pathway

Free Radical Biology & MedicineFebruary 22, 2020
Peng SongZhen-Guo Ma
1
Biogerontology

MicroRNAs, DNA damage response and ageing

BiogerontologyFebruary 19, 2020
Maryam MajidiniaBahman Yousefi

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