Peripheral Causes of Neurodegeneration

Neurodegenerative diseases may be caused in part by triggers from peripheral body systems or inflammation mediated by brain cells other than neurons. Understanding these peripheral factors is necessary for designing treatments. Additionally, genetic tools allowing for delivery of transgenes past the blood-brain barrier are important for treatments of any CNS diseases. Discover the latest research on neurodegenerative disorders, their peripheral causes, and viral vectors for CNS delivery here.

December 7, 2021

Drosophila as a model to study autophagy in neurodegenerative diseases and digestive tract.

IUBMB Life
Fei-Yang TzouChih-Chiang Chan
December 6, 2021
Review

A Comprehensive Review of Neuronal Changes in Diabetics.

Curēus
Rudy LunaFenil Gandhi
December 6, 2021
Open Access

Anti-Inflammatory and Anti-Oxidative Effects of AM404 in IL-1β-Stimulated SK-N-SH Neuroblastoma Cells.

Frontiers in Pharmacology
Matthias ApweilerBernd L Fiebich
December 6, 2021
Review
Open Access

Role of G Protein-Coupled Receptors in Microglial Activation: Implication in Parkinson's Disease.

Frontiers in Aging Neuroscience
Chao GuMei Wang
December 6, 2021
Review

Local and remote interactions between macrophages and microglia in neurological conditions.

Current Opinion in Immunology
Séverine Boillée
December 4, 2021
Review
Open Access

Therapeutic Potential of α-Synuclein Evolvability for Autosomal Recessive Parkinson's Disease.

Parkinson's Disease
Jianshe WeiMakoto Hashimoto
December 3, 2021

Neuroinflammation in Huntington's disease: A starring role for astrocyte and microglia.

Current Neuropharmacology
Julieta SabaCarla Caruso
December 3, 2021

The metabolic signaling of the nucleoredoxin-like 2 gene supports brain function.

Redox Biology
Céline JaillardThierry Léveillard
December 2, 2021
Review

Metalloproteinases and their inhibitors in neurological disease.

Naunyn-Schmiedeberg's Archives of Pharmacology
Edgar R Lopez-Navarro, Jose Gutierrez
December 2, 2021
Review

The HERC proteins and the nervous system.

Seminars in Cell & Developmental Biology
Eva M Pérez-VillegasJose Luis Rosa
December 2, 2021
Review

Imaging neuroinflammation with TSPO: A new perspective on the cellular sources and subcellular localization.

Pharmacology & Therapeutics
Tomás R GuilarteDiana J Azzam
December 1, 2021

Inflammasome activation in neurodegenerative diseases.

Essays in Biochemistry
Kishore Aravind Ravichandran, Michael T Heneka
November 29, 2021
Review

The Impact of Alcohol-Induced Dysbiosis on Diseases and Disorders of the Central Nervous System.

Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology
Xiangqian LiuSulie L Chang
November 29, 2021
Review

Embelin: A novel XIAP inhibitor for the prevention and treatment of chronic diseases.

Journal of Biochemical and Molecular Toxicology
Uzini Devi DaimaryAjaikumar B Kunnumakkara
November 29, 2021
Review

A MDS Evidence-Based Review on Treatments for Huntington's Disease.

Movement Disorders : Official Journal of the Movement Disorder Society
Joaquim J FerreiraCristina Sampaio
November 29, 2021

Engineered Solid Lipid Nanoparticles and Nanostructured Lipid Carriers as New Generations of Blood-Brain Barrier Transmitters.

ACS Chemical Neuroscience
Mahtab AmiriZhila Izadi
November 29, 2021
Review

Updates on the Genetics of Parkinson's Disease: Clinical Implications and Future Treatment.

Acta Neurologica Taiwanica
Yung-Tsai ChuRuey-Meei Wu

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